Cisplatin-induced neurotoxicity in vivo can be alleviated by riboflavin under photoillumination

Cancer Biotherapy and Radiopharmaceuticals

Volumn 28, Issue 2, 2013, Pages 160-168

  Hassan, Iftekhar ^a   Chibber, Sandesh ^a   Khan, Aijaz A ^b   Naseem, Imrana ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

^b ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

cisplatin; free radicals; neurotoxicity; photoillumination; riboflavin

Indexed keywords

CATALASE; CISPLATIN; COPPER ZINC SUPEROXIDE DISMUTASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE REDUCTASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; NITRIC OXIDE; RIBOFLAVIN; THIOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN FUNCTION; BRAIN LEVEL; BRAIN WEIGHT; CHEMORADIOTHERAPY; CONTROLLED STUDY; DOSE RESPONSE; DRUG INDUCED DISEASE; ENZYME ACTIVITY; HISTOPATHOLOGY; ILLUMINATION; IN VIVO STUDY; LIGHT EXPOSURE; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; OXIDATION; PHOTOSENSITIZATION; PRIORITY JOURNAL;

ANIMALS; ANTIOXIDANTS; BRAIN; CISPLATIN; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LIGHT; LIPID PEROXIDATION; MALE; MICE; NEUROTOXICITY SYNDROMES; OXIDATION-REDUCTION; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; RADIATION-SENSITIZING AGENTS; RIBOFLAVIN;

EID: 84874701777     PISSN: 10849785     EISSN: 15578852     Source Type: Journal    
DOI: 10.1089/cbr.2012.1312     Document Type: Article

References (43)

1. Tarladacalisir YT, Kanter M, Uygun M. Protective effect of vitamin C on cisplatin-induced renal damage: A light and electronic microscopic study. Ren Fail 2008;30:1.
2. Mc Donald ES, Randon KR, Knight A, Windebank AJ. Cisplatin preferentially binds to DNA in dorsal root ganglion neurons in vitro and in vivo: A potential mechanism of neurotoxicity. Neurobiol Dis 2005;18:305.
3. Windebank AJ, Grisold W. Chemotherapy induced neuropathy. J Peripher Nerv Syst 2008;13:27.
4. Siddik ZH. Cisplatin: Mode of cytotoxic action and molecular basis of resistance. Oncogene 2003;22:7265.
5. Ta LE, Espeset L, Podratz J, Windebank AJ. Neurotoxicity of oxaliplatin and cisplatin for dorsal root ganglion neurons correlates with platinum-DNA binding. Neurotoxicology 2006;27:992.
6. Minami T, Okazaki J, Kawabata A, et al. Lipopolysaccharideinduced platinum accumulation in the cerebral cortex after cisplatin administration in mice: Involvement of free radicals. Environ Toxicol Pharmacol 1996;2:321.
7. Chirino YI, Trujillo J, Sanchez-Gonzalez DJ, et al. Selective iNOS inhibition reduces renal damage induced by cisplatin. Toxicol Lett 2008;176:48.
8. Kumari MV, Yoneda T, Hiramatsu M. Scavenging activity of beta catechin on reactive oxygen species generated by photosensitization of riboflavin. Biochem Mol Biol Int 1996;38:1163.
9. Perumal SS, Shathi P, Sachdanandam P. Augmented efficiency of tamoxifen in rat breast tumorigenesis when gavaged along with riboflavin; niacin and CoQ 10: Effects on lipid peroxidation and antioxidants in mitochondria. Chem Biol Interact 2005;152:49.
10. Munoz MA, Pacheco A, Becker MI, et al. Different cell death mechanisms are induced by a hydrophobic flavin in human tumor cells after visible light irradiation. J Photochem Photobiol B: Biol 2011;103:57.
11. De Souza Queiroz KC, Zambuzzi WF, Santos De Souza AC, et al. A possible anti-proliferative and anti-metastatic effect of irradiated riboflavin in solid tumors. Cancer Lett 2007; 258:126.
12. Rivlin RS. Riboflavin and cancer: A review. Cancer Res 1973;33:1977.
13. Husain E, Naseem I. Riboflavin mediated cellular photoinhibition of cisplatin-induced oxidative DNA breakage in mice keratinocytes. Photodermatol Photoimmunol Photomed 2008;24:301.
14. Hassan I, Chibber S, Naseem I. Ameliorative effect of riboflavin on cisplatin induced nephrotoxicity and hepatotoxicity under photoillumination. Food Chem toxicol 2010;48: 2052.
15. Hassan I, Chibber S, Khan AA, Naseem I. Riboflavin ameliorates cisplatin induced toxicities under photoillumination. Plos One 2012;7:e36273.
16. Marklund S, Marklund G. Involvement of superoxide anion radical in the auto-oxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974; 47:469.
17. Aebi H. Catalase in vitro. Meth Enzymol 1984;105:121.
18. Carberg I, Mannervik B. Glutathione reductase. Meth Enzymol 1985;113:484.
19. Beuge JA, Aust SD. Microsomal lipid peroxidation. Meth Enzymol 1978;52:302.
20. Jollow DJ, Mitchell JR, Zampaglione N, Gillette Jr. Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3, 4-bromobenzene oxide as hepatotoxic metabolite. Pharmacology 1974;11:151.
21. Sedalk J, Lindsay RH. Estimation of total, protein-bound and non-protein sulfydryl groups in tissues with Ellman's reagent. Anal Biochem 1968;25:192.
22. Shonk CE, Boxer GE. Enzyme patterns in human tissues. I. Methods for the determination of glycolytic enzymes. Cancer Res 1964;24:709.
23. Kornberg A. Lactate dehydrogenase of muscle. Meth Enzymol 1955;1:441-443.
24. Habig WH, Pabst MJ, Jokoby WB. Glutathione S-transferase: The first enzymatic step in mercapturic acid formation. J Biol Chem 1974;249:7130.
25. Chirino YI, Pedraza-Chaverri J. Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity. Exp Toxicol Pathol 2009;61:223.
26. Minami T, Ichii M, Okazaki Y. Detection of platinum in the brain of mice treated with cisplatin and subjected to shortterm hypoxia. J Pharm Pharmacol 1996;48:505.
27. Minami T, Okazaki J, Kawabata A, et al. Penetration of cisplatin into mouse brain by lipopolysaccharide. Toxicology 1998;130:107.
28. Ozyurt B, Gulec M, Ozyurt H, et al. The effect of antioxidant caffeic acid phenethyl ester (CAPE) on some enzyme activities in cisplatin-induced neurotoxicity in rats. Eur J Gen Med 2006;3:167.
29. Caveletti G, Minoia C, Schieppati M, Tredici G. Protective effects of glutathione on cisplatin neurotoxicity in rats. Int J Radiat Oncol Biol Phy 1994;29:771.
30. Dzagnidze A, Katsarava Z, Makhalova J, et al. Repair capacity for platinum-DNA adducts determines the severity of cisplatin-induced peripheral neuropathy. J Neurosci 2007;27:9451.
31. Moncada S. Nitric oxide: Discovery and impact on clinical medicine. JRSM 1999;92:164.
32. Son K, Kim Y-M. In vivo cisplatin-exposed macrophages increase immunostimulant-induced nitric oxide synthase for tumor cell killing. Cancer Res 1995;55:5524.
33. Oury TD, Ho YS, Piantadosi CA, Crapo JD. Extracellular superoxide dismutase, nitric oxide and central nervous system O2 toxicity. Proc Natl Acad Sci U S A 1992;89:9715.
34. Anda T, Yamashita H, Khalid H, et al. Effect of tumor necrosis factor-alpha on the permeability of bovine brain microvessel endothelial cell monolayers. Neurol Res 1997;19:369.
35. Caveletti G, Tredici G, Marmiroli P, et al. Morphological study of sensory neurons and peripheral nerve changes induced by chronic cisplatin (DDP) administration in rats. Acta Neuropathol 1992;84:364.
36. Donzelli E, Carfi M, Miloso M, et al. Neurotoxicity of platinum compounds: Comparison of the effects of cisplatin and oxaliplatin on the human neuroblastoma cell line SH-SY5Y. J Neuro-Oncol 2004;67:65.
37. Melli G, Taiana M, Comazzi F, et al. Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy. Exp Neurol 2008;214:276.
38. De souza ACS, Kodach L, Gadelha FR, et al. A promising action of riboflavin as a mediator of leukemia cell death. Apoptosis 2006;11:1761.
39. Miyashita T, Masayoshi H, Hanada M, Reed JC. Identification of a p53-dependent negative response element in bcl-2 gene. Cancer Res 1994;54:3131.
40. Sanchez-Perez I, Murguia JR, Perona R. Cisplatin induces a persistent activation of JNK that is related to cell death. Oncogene 1998;16:533.
41. Gill JS, Windebank AJ. Cisplatin-induced apoptosis in rat dorsal ganglion neurons in associated with attempted entry into the cell cycle. J Clin Invest 1998;101:2842.
42. Lilge L, Portnoy M, Wilson BC. Apoptosis induced in vivo by photodynamic therapy in normal brain and intracranial tumor tissues. Br J Cancer 2000;83:1110.
43. Chaves Neto AH, Yano CL, Paredes-Gamero EJ, et al. Riboflavin and photoproducts in MC3T3-E1 differentiation. Toxicol In Vitro 2010;24:1911.