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Volumn 125, Issue 23, 2012, Pages 5850-5859

A key phosphorylation site in AC8 mediates regulation of Ca2+-dependent camp dynamics by an AC8- AKAP79-PKA signalling complex

Author keywords

Adenylyl cyclase; AKAP; Calcium; Phosphorylation; PKA

Indexed keywords

A KINASE ANCHORING PROTEIN 79; ADENYLATE CYCLASE; ADENYLATE CYCLASE 8; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN; UNCLASSIFIED DRUG;

EID: 84874674191     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.111427     Document Type: Article
Times cited : (29)

References (50)
  • 3
    • 0033579464 scopus 로고    scopus 로고
    • Sequence and structure-based prediction of eukaryotic protein phosphorylation sites
    • Blom, N., Gammeltoft, S. and Brunak, S. (1999). Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J. Mol. Biol. 294, 1351-1362.
    • (1999) J. Mol. Biol. , vol.294 , pp. 1351-1362
    • Blom, N.1    Gammeltoft, S.2    Brunak, S.3
  • 5
    • 0026795614 scopus 로고
    • Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins, Characterization of AKAP 79
    • Carr, D. W., Stofko-Hahn, R. E., Fraser, I. D., Cone, R. D. and Scott, J. D. (1992). Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79. J. Biol. Chem. 267, 16816-16823.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16816-16823
    • Carr, D.W.1    Stofko-Hahn, R.E.2    Fraser, I.D.3    Cone, R.D.4    Scott, J.D.5
  • 6
    • 0031456052 scopus 로고    scopus 로고
    • Adenylyl cyclase 6 is selectively regulated by protein kinase A phosphorylation in a region involved in Galphas stimulation
    • Chen, Y., Harry, A., Li, J., Smit, M. J., Bai, X., Magnusson, R., Pieroni, J. P., Weng, G. and Iyengar, R. (1997). Adenylyl cyclase 6 is selectively regulated by protein kinase A phosphorylation in a region involved in Galphas stimulation. Proc. Natl. Acad. Sci. USA 94, 14100-14104.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14100-14104
    • Chen, Y.1    Harry, A.2    Li, J.3    Smit, M.J.4    Bai, X.5    Magnusson, R.6    Pieroni, J.P.7    Weng, G.8    Iyengar, R.9
  • 9
    • 39149116365 scopus 로고    scopus 로고
    • Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences
    • Coin, I., Beyermann, M. and Bienert, M. (2007). Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences. Nat. Protoc. 2, 3247-3256.
    • (2007) Nat. Protoc. , vol.2 , pp. 3247-3256
    • Coin, I.1    Beyermann, M.2    Bienert, M.3
  • 11
    • 31044435283 scopus 로고    scopus 로고
    • A direct interaction between the N terminus of adenylyl cyclase AC8 and the catalytic subunit of protein phosphatase 2A
    • Crossthwaite, A. J., Ciruela, A., Rayner, T. F. and Cooper, D. M. F. (2006). A direct interaction between the N terminus of adenylyl cyclase AC8 and the catalytic subunit of protein phosphatase 2A. Mol. Pharmacol. 69, 608-617.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 608-617
    • Crossthwaite, A.J.1    Ciruela, A.2    Rayner, T.F.3    Cooper, D.M.F.4
  • 12
    • 80053007224 scopus 로고    scopus 로고
    • Palmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8
    • Delint-Ramirez, I., Willoughby, D., Hammond, G. V., Ayling, L. J. and Cooper, D. M. F. (2011). Palmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8. J. Biol. Chem. 286, 32962-32975.
    • (2011) J. Biol. Chem. , vol.286 , pp. 32962-32975
    • Delint-Ramirez, I.1    Willoughby, D.2    Hammond, G.V.3    Ayling, L.J.4    Cooper, D.M.F.5
  • 13
    • 0032522719 scopus 로고    scopus 로고
    • Membrane-targeting sequences on AKAP79 bind phosphatidylinositol-4, 5-bisphosphate
    • Dell'Acqua, M. L., Faux, M. C., Thorburn, J., Thorburn, A. and Scott, J. D. (1998). Membrane-targeting sequences on AKAP79 bind phosphatidylinositol-4, 5-bisphosphate. EMBO J. 17, 2246-2260.
    • (1998) EMBO J , vol.17 , pp. 2246-2260
    • Dell'Acqua, M.L.1    Faux, M.C.2    Thorburn, J.3    Thorburn, A.4    Scott, J.D.5
  • 14
    • 0142125207 scopus 로고    scopus 로고
    • Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1
    • Delmeire, D., Flamez, D., Hinke, S. A., Cali, J. J., Pipeleers, D. and Schuit, F. (2003). Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1. Diabetologia 46, 1383-1393.
    • (2003) Diabetologia , vol.46 , pp. 1383-1393
    • Delmeire, D.1    Flamez, D.2    Hinke, S.A.3    Cali, J.J.4    Pipeleers, D.5    Schuit, F.6
  • 15
    • 70350469968 scopus 로고    scopus 로고
    • Adenylyl cyclase-A-kinase anchoring protein complexes: the next dimension in cAMP signaling
    • Dessauer, C. W. (2009). Adenylyl cyclase-A-kinase anchoring protein complexes: the next dimension in cAMP signaling. Mol. Pharmacol. 76, 935-941.
    • (2009) Mol. Pharmacol. , vol.76 , pp. 935-941
    • Dessauer, C.W.1
  • 16
    • 31144458770 scopus 로고    scopus 로고
    • Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells
    • Dyachok, O., Isakov, Y., Sågetorp, J. and Tengholm, A. (2006). Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells. Nature 439, 349-352.
    • (2006) Nature , vol.439 , pp. 349-352
    • Dyachok, O.1    Isakov, Y.2    Sågetorp, J.3    Tengholm, A.4
  • 17
    • 77951985322 scopus 로고    scopus 로고
    • AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors
    • Efendiev, R., Samelson, B. K., Nguyen, B. T., Phatarpekar, P. V., Baameur, F., Scott, J. D. and Dessauer, C. W. (2010). AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors. J. Biol. Chem. 285, 14450-14458.
    • (2010) J. Biol. Chem. , vol.285 , pp. 14450-14458
    • Efendiev, R.1    Samelson, B.K.2    Nguyen, B.T.3    Phatarpekar, P.V.4    Baameur, F.5    Scott, J.D.6    Dessauer, C.W.7
  • 18
    • 0032520118 scopus 로고    scopus 로고
    • Developmental profile and synaptic origin of early network oscillations in the CA1 region of rat neonatal hippocampus
    • Garaschuk, O., Hanse, E. and Konnerth, A. (1998). Developmental profile and synaptic origin of early network oscillations in the CA1 region of rat neonatal hippocampus. J. Physiol. 507, 219-236.
    • (1998) J. Physiol. , vol.507 , pp. 219-236
    • Garaschuk, O.1    Hanse, E.2    Konnerth, A.3
  • 19
    • 0037104782 scopus 로고    scopus 로고
    • Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin
    • Gomez, L. L., Alam, S., Smith, K. E., Horne, E. and Dell'Acqua, M. L. (2002). Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin. J. Neurosci. 22, 7027-7044.
    • (2002) J. Neurosci. , vol.22 , pp. 7027-7044
    • Gomez, L.L.1    Alam, S.2    Smith, K.E.3    Horne, E.4    Dell'Acqua, M.L.5
  • 20
    • 0033962352 scopus 로고    scopus 로고
    • Caffeine exerts a dual effect on capacitative calcium entry in Xenopus oocytes
    • Hague, F., Matifat, F., Brûlé, G. and Collin, T. (2000). Caffeine exerts a dual effect on capacitative calcium entry in Xenopus oocytes. Cell. Signal. 12, 31-35.
    • (2000) Cell. Signal. , vol.12 , pp. 31-35
    • Hague, F.1    Matifat, F.2    Brûlé, G.3    Collin, T.4
  • 22
    • 0026443535 scopus 로고
    • Enhanced effectiveness of pulsatile 39, 59-cyclic adenosine monophosphate in stimulating prolactin and a-subunit gene expression
    • Haisenleder, D. J., Yasin, M. and Marshall, J. C. (1992). Enhanced effectiveness of pulsatile 39,59-cyclic adenosine monophosphate in stimulating prolactin and a-subunit gene expression. Endocrinology 131, 3027-3033.
    • (1992) Endocrinology , vol.131 , pp. 3027-3033
    • Haisenleder, D.J.1    Yasin, M.2    Marshall, J.C.3
  • 26
    • 70350351409 scopus 로고    scopus 로고
    • Radial spoke protein 3 is a mammalian protein kinase A-anchoring protein that binds ERK1/2
    • Jivan, A., Earnest, S., Juang, Y. C. and Cobb, M. H. (2009). Radial spoke protein 3 is a mammalian protein kinase A-anchoring protein that binds ERK1/2. J. Biol. Chem. 284, 29437-29445.
    • (2009) J. Biol. Chem. , vol.284 , pp. 29437-29445
    • Jivan, A.1    Earnest, S.2    Juang, Y.C.3    Cobb, M.H.4
  • 29
    • 0029887701 scopus 로고    scopus 로고
    • Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein
    • Klauck, T. M., Faux, M. C., Labudda, K., Langeberg, L. K., Jaken, S. and Scott, J. D. (1996). Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein. Science 271, 1589-1592.
    • (1996) Science , vol.271 , pp. 1589-1592
    • Klauck, T.M.1    Faux, M.C.2    Labudda, K.3    Langeberg, L.K.4    Jaken, S.5    Scott, J.D.6
  • 30
    • 79958848133 scopus 로고    scopus 로고
    • Identification of AKAP79 as a protein phosphatase 1 catalytic binding protein
    • Le, A. V., Tavalin, S. J. and Dodge-Kafka, K. L. (2011). Identification of AKAP79 as a protein phosphatase 1 catalytic binding protein. Biochemistry 50, 5279-5291.
    • (2011) Biochemistry , vol.50 , pp. 5279-5291
    • Le, A.V.1    Tavalin, S.J.2    Dodge-Kafka, K.L.3
  • 31
    • 0041319417 scopus 로고    scopus 로고
    • Identification of an IQGAP1/ AKAP79 complex in beta-cells
    • Nauert, J. B., Rigas, J. D. and Lester, L. B. (2003). Identification of an IQGAP1/ AKAP79 complex in beta-cells. J. Cell. Biochem. 90, 97-108.
    • (2003) J. Cell. Biochem. , vol.90 , pp. 97-108
    • Nauert, J.B.1    Rigas, J.D.2    Lester, L.B.3
  • 32
    • 33847236890 scopus 로고    scopus 로고
    • cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map
    • Nicol, X., Voyatzis, S., Muzerelle, A., Narboux-Nême, N., Südhof, T. C., Miles, R. and Gaspar, P. (2007). cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map. Nat. Neurosci. 10, 340-347.
    • (2007) Nat. Neurosci. , vol.10 , pp. 340-347
    • Nicol, X.1    Voyatzis, S.2    Muzerelle, A.3    Narboux-Nême, N.4    Südhof, T.C.5    Miles, R.6    Gaspar, P.7
  • 33
    • 0037421222 scopus 로고    scopus 로고
    • Imaging kinase- AKAP79-phosphatase scaffold complexes at the plasma membrane in living cells using FRET microscopy
    • Oliveria, S. F., Gomez, L. L. and Dell'Acqua, M. L. (2003). Imaging kinase- AKAP79-phosphatase scaffold complexes at the plasma membrane in living cells using FRET microscopy. J. Cell Biol. 160, 101-112.
    • (2003) J. Cell Biol. , vol.160 , pp. 101-112
    • Oliveria, S.F.1    Gomez, L.L.2    Dell'Acqua, M.L.3
  • 35
    • 33947643561 scopus 로고    scopus 로고
    • A-kinase anchoring protein 150 in the mouse brain is concentrated in areas involved in learning and memory
    • Ostroveanu, A., Van der Zee, E. A., Dolga, A. M., Luiten, P. G., Eisel, U. L. and Nijholt, I. M. (2007). A-kinase anchoring protein 150 in the mouse brain is concentrated in areas involved in learning and memory. Brain Res. 1145, 97-107.
    • (2007) Brain Res , vol.1145 , pp. 97-107
    • Ostroveanu, A.1    Van der Zee, E.A.2    Dolga, A.M.3    Luiten, P.G.4    Eisel, U.L.5    Nijholt, I.M.6
  • 36
    • 52949130234 scopus 로고    scopus 로고
    • The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain
    • Piggott, L. A., Bauman, A. L., Scott, J. D. and Dessauer, C. W. (2008). The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain. Proc. Natl. Acad. Sci. USA 105, 13835-13840.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 13835-13840
    • Piggott, L.A.1    Bauman, A.L.2    Scott, J.D.3    Dessauer, C.W.4
  • 38
    • 33645644069 scopus 로고    scopus 로고
    • cAMP-dependent protein kinase postsynaptic localization regulated by NMDA receptor activation through translocation of an A-kinase anchoring protein scaffold protein
    • Smith, K. E., Gibson, E. S. and Dell'Acqua, M. L. (2006). cAMP-dependent protein kinase postsynaptic localization regulated by NMDA receptor activation through translocation of an A-kinase anchoring protein scaffold protein. J. Neurosci. 26, 2391-2402.
    • (2006) J. Neurosci. , vol.26 , pp. 2391-2402
    • Smith, K.E.1    Gibson, E.S.2    Dell'Acqua, M.L.3
  • 39
    • 33846011455 scopus 로고    scopus 로고
    • Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells
    • Stefan, E., Wiesner, B., Baillie, G. S., Mollajew, R., Henn, V., Lorenz, D., Furkert, J., Santamaria, K., Nedvetsky, P., Hundsrucker, C. et al. (2007). Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells. J. Am. Soc. Nephrol. 18, 199-212.
    • (2007) J. Am. Soc. Nephrol. , vol.18 , pp. 199-212
    • Stefan, E.1    Wiesner, B.2    Baillie, G.S.3    Mollajew, R.4    Henn, V.5    Lorenz, D.6    Furkert, J.7    Santamaria, K.8    Nedvetsky, P.9    Hundsrucker, C.10
  • 40
    • 0027431842 scopus 로고
    • Calcium oscillations in pancreatic acinar cells, evoked by the cholecystokinin analogue JMV-180, depend on functional inositol 1,4,5-trisphosphate receptors
    • Thorn, P. and Petersen, O. H. (1993). Calcium oscillations in pancreatic acinar cells, evoked by the cholecystokinin analogue JMV-180, depend on functional inositol 1,4,5-trisphosphate receptors. J. Biol. Chem. 268, 23219-23221.
    • (1993) J. Biol. Chem. , vol.268 , pp. 23219-23221
    • Thorn, P.1    Petersen, O.H.2
  • 42
    • 0037334533 scopus 로고    scopus 로고
    • Calmodulin-regulated adenylyl cyclases: cross-talk and plasticity in the central nervous system
    • Wang, H. and Storm, D. R. (2003). Calmodulin-regulated adenylyl cyclases: cross-talk and plasticity in the central nervous system. Mol. Pharmacol. 63, 463-468.
    • (2003) Mol. Pharmacol. , vol.63 , pp. 463-468
    • Wang, H.1    Storm, D.R.2
  • 43
    • 0242693339 scopus 로고    scopus 로고
    • Type 8 adenylyl cyclase is targeted to excitatory synapses and required for mossy fiber long-term potentiation
    • Wang, H., Pineda, V. V., Chan, G. C., Wong, S. T., Muglia, L. J. and Storm, D. R. (2003). Type 8 adenylyl cyclase is targeted to excitatory synapses and required for mossy fiber long-term potentiation. J. Neurosci. 23, 9710-9718.
    • (2003) J. Neurosci. , vol.23 , pp. 9710-9718
    • Wang, H.1    Pineda, V.V.2    Chan, G.C.3    Wong, S.T.4    Muglia, L.J.5    Storm, D.R.6
  • 44
    • 33645222621 scopus 로고    scopus 로고
    • 2+ stimulation of adenylyl cyclase generates dynamic oscillations in cyclic AMP
    • 2+ stimulation of adenylyl cyclase generates dynamic oscillations in cyclic AMP. J. Cell Sci. 119, 828-836.
    • (2006) J. Cell Sci. , vol.119 , pp. 828-836
    • Willoughby, D.1    Cooper, D.M.F.2
  • 45
    • 34447510936 scopus 로고    scopus 로고
    • 2+ regulation of adenylyl cyclases in cAMP microdomains
    • 2+ regulation of adenylyl cyclases in cAMP microdomains. Physiol. Rev. 87, 965-1010.
    • (2007) Physiol. Rev , vol.87 , pp. 965-1010
    • Willoughby, D.1    Cooper, D.M.F.2
  • 46
    • 33646787840 scopus 로고    scopus 로고
    • An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics
    • Willoughby, D., Wong, W., Schaack, J., Scott, J. D. and Cooper, D. M. F. (2006). An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics. EMBO J 25, 2051-2061.
    • (2006) EMBO J , vol.25 , pp. 2051-2061
    • Willoughby, D.1    Wong, W.2    Schaack, J.3    Scott, J.D.4    Cooper, D.M.F.5
  • 49
    • 10044253425 scopus 로고    scopus 로고
    • AKAP signalling complexes: focal points in space and time
    • Wong, W. and Scott, J. D. (2004). AKAP signalling complexes: focal points in space and time. Nat. Rev. Mol. Cell Biol. 5, 959-970.
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 959-970
    • Wong, W.1    Scott, J.D.2
  • 50
    • 44649083832 scopus 로고    scopus 로고
    • Ca-stimulated type 8 adenylyl cyclase is required for rapid acquisition of novel spatial information and for working/ episodic-like memory
    • Zhang, M., Moon, C., Chan, G. C. K., Yang, L., Zheng, F., Conti, A. C., Muglia, L., Muglia, L. J., Storm, D. R. and Wang, H. (2008). Ca-stimulated type 8 adenylyl cyclase is required for rapid acquisition of novel spatial information and for working/ episodic-like memory. J. Neurosci. 28, 4736-4744.
    • (2008) J. Neurosci. , vol.28 , pp. 4736-4744
    • Zhang, M.1    Moon, C.2    Chan, G.C.K.3    Yang, L.4    Zheng, F.5    Conti, A.C.6    Muglia, L.7    Muglia, L.J.8    Storm, D.R.9    Wang, H.10


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