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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 6, 2013, Pages 1622-1625

Substituted piperidinyl glycinyl 2-cyano-4,5-methano pyrrolidines as potent and stable dipeptidyl peptidase IV inhibitors

(8) Zhao, Guohua a Kwon, Chet a Wang, Aiying a Robertson, James G a Marcinkeviciene, Jovita a Parker, Rex A a Kirby, Mark S a Hamann, Lawrence G a

a BRISTOL MYERS SQUIBB (United States)

Author keywords

Dipeptidyl peptidase IV inhibitor; Piperidine; Pyrrolidine; Type 2 diabetes

Indexed keywords

DIPEPTIDYL PEPTIDASE IV INHIBITOR; LINAGLIPTIN; PIPERIDINE DERIVATIVE; PYRROLIDINE DERIVATIVE; SAXAGLIPTIN; SITAGLIPTIN; VILDAGLIPTIN;

ARTICLE; DRUG ACTIVITY; DRUG INHIBITION; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; NON INSULIN DEPENDENT DIABETES MELLITUS; STRUCTURE ACTIVITY RELATION;

DIPEPTIDYL PEPTIDASE 4; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; HUMANS; HYDROGEN-ION CONCENTRATION; PIPERIDINES; PROTEIN BINDING; PYRROLIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 84874654348 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.01.104 Document Type: Article

Times cited : (12)

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