Extending the versatility of the Hemetsberger-Knittel indole synthesis through microwave and flow chemistry

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 6, 2013, Pages 1740-1742

  Ranasinghe, Nadeesha ^a   Jones, Graham B ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Click chemistry; Decarboxylation; Flow; Fluorine labeling; Indoles; Microwave; Nitrene insertion; PLX 4032

Indexed keywords

INDOLE DERIVATIVE; VEMURAFENIB;

ARTICLE; CATALYST; CHEMICAL MODIFICATION; CLICK CHEMISTRY; CYCLOADDITION; DECARBOXYLATION; DRUG HYDROLYSIS; DRUG SYNTHESIS; FLOW; FRIEDEL CRAFTS REACTION; HEMETSBERGER KNITTEL REACTION; MICROWAVE IRRADIATION; REACTION TIME;

ANTINEOPLASTIC AGENTS; CLICK CHEMISTRY; CYCLOADDITION REACTION; FLUORINE; INDOLES; MICROWAVES; PEPTIDES; SULFONAMIDES;

EID: 84874652792     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.01.066     Document Type: Article

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