Evaluation of a dithiocarbamate derivative as an inhibitor of human glutaredoxin-1

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 28, Issue 3, 2013, Pages 456-462

  Sadhu, Satya S ^a   Callegari, Eduardo ^b   Zhao, Yong ^c   Guan, Xiangming ^a   Seefeldt, Teresa ^a  

^a SOUTH DAKOTA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTH DAKOTA   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Glutaredoxin; Glutathione; Glutathionylation; Thiol

Indexed keywords

2 ACETYLAMINO 3 [4 (2 ACETYLAMINO 2 CARBOXYETHYL SULFANYLTHIOCARBONYLAMINO)PHENYLTHIOCARBAMOYLSULFANYL]PROPIONIC ACID; DITHIOCARBAMIC ACID DERIVATIVE; ENZYME INHIBITOR; GLUTAREDOXIN; GLUTAREDOXIN 1; UNCLASSIFIED DRUG; 2 ACETYLAMINO 3 [4 (2 ACETYLAMINO 2 CARBOXYETHYLSULFANYLTHIOCARBONYLAMINO)PHENYLTHIOCARBOMOYLSULFANYL]PROPIONIC ACID;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COVALENT BOND; DIALYSIS; DRUG SCREENING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; OVARY CANCER; PRIORITY JOURNAL; CONCENTRATION RESPONSE; DRUG MECHANISM; DRUG POTENCY; FEMALE; OVARIAN CANCER CELL LINE;

ACETYLCYSTEINE; CELL LINE, TUMOR; DIALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; GLUTAREDOXINS; GLUTATHIONE; HUMANS; THIOCARBAMATES;

EID: 84874615570     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2011.649267     Document Type: Article

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