Severe bleeding in surgical and trauma patients: The role of fibrinogen replacement therapy

Thrombosis Research

Volumn 130, Issue SUPPL. 2, 2012, Pages

  Spahn, Donat R ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Coagulopathy; Fibrinogen; Haemocomplettan ; Rotation thromboelastometry; ROTEM TEG ; Surgery; Thromboelastography; Trauma

Indexed keywords

FIBRINOGEN; FIBRINOGEN CONCENTRATE;

BLEEDING; CONFERENCE PAPER; EMERGENCY CARE; ERYTHROCYTE TRANSFUSION; FIBRINOGEN BLOOD LEVEL; HUMAN; POINT OF CARE TESTING; PRACTICE GUIDELINE; PRIORITY JOURNAL; SURGICAL PATIENT; THROMBOELASTOGRAPHY; TREATMENT OUTCOME;

BLOOD LOSS, SURGICAL; COAGULANTS; FIBRINOGEN; HEMORRHAGE; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; WOUNDS AND INJURIES;

EID: 84874606367     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/S0049-3848(13)70006-9     Document Type: Conference Paper

References (24)

1. PM Mannucci Treatment of von Willebrand's Disease N Engl J Med 351 2004 683 694
2. DM Monroe, HR Roberts, M Hoffman Platelet procoagulant complex assembly in a tissue factor-initiated system Br J Haematol 88 1994 364 371 (Pubitemid 24318187)
3. TM McLoughlin, JL Fontana, B Alving, PD Mongan, R Bünger Profound normovolemic hemodilution: hemostatic effects in patients and in a porcine model Anesth Analg 83 1996 459 465 (Pubitemid 26296348)
4. ST Hiippala, GJ Myllylä, EM Vahtera Hemostatic factors and replacement of major blood loss with plasma-poor red cell concentrates Anesth Analg 81 1995 360 365
5. D Fries, WZ Martini Role of fibrinogen in trauma-induced coagulopathy Br J Anaesth 105 2010 116 121
6. MS Carling, A Jeppsson, P Wessberg, A Henriksson, F Baghaei, H Brisby Preoperative fibrinogen plasma concentration is associated with perioperative bleeding and transfusion requirements in scoliosis surgery Spine (Phila Pa 1976) 36 2011 549 555
7. M Karlsson, L Ternström, M Hyllner, F Baghaei, S Nilsson, A Jeppsson Plasma fibrinogen level, bleeding, and transfusion after on-pump coronary artery bypass grafting surgery: a prospective observational study Transfusion 48 2008 2152 2158
8. L Ternström, V Radulovic, M Karlsson, F Baghaei, M Hyllner, A Bylock et al. Plasma activity of individual coagulation factors, hemodilution and blood loss after cardiac surgery: a prospective observational study Thromb Res 126 2010 e128 e133
9. DR Spahn, MT Ganter Towards early individual goal-directed coagulation management in trauma patients Br J Anaesth 105 2010 103 105
10. K Brohi, MJ Cohen, RA Davenport Acute coagulopathy of trauma: mechanism, identification and effect Curr Opin Crit Care 13 2007 680 685 (Pubitemid 350059533)
11. R Rossaint, B Bouillon, V Cerny, TJ Coats, J Duranteau, E Fernández-Mondéjar et al. Management of bleeding following major trauma: an updated European guideline Crit Care 14 2010 R52
12. K Brohi, J Singh, M Heron, T Coats Acute traumatic coagulopathy J Trauma 54 2003 1127 1130 (Pubitemid 36764882)
13. C Fenger-Eriksen, M Lindberg-Larsen, AQ Christensen, J Ingerslev, B Sørensen Fibrinogen concentrate substitution therapy in patients with massive haemorrhage and low plasma fibrinogen concentrations Br J Anaesth 101 2008 769 773
14. M Karlsson, L Ternström, M Hyllner, F Baghaei, A Flinck, S Skrtic et al. Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study Thromb Haemost 102 2009 137 144
15. C Fenger-Eriksen, TM Jensen, BS Kristensen, KM Jensen, E Tønnesen, J Ingerslev et al. Fibrinogen substitution improves whole blood clot firmness after dilution with hydroxyethyl starch in bleeding patients undergoing radical cystectomy: a randomized, placebo-controlled clinical trial J Thromb Haemost 7 2009 795 802
16. HK Stinger, PC Spinella, JG Perkins, KW Grathwohl, J Salinas, WZ Martini et al. The ratio of fibrinogen to red cells transfused affects survival in casualties receiving massive transfusions at an army combat support hospital J Trauma 64 2 Suppl 2008 S79 S85
17. IJ Mackie, S Kitchen, SJ Machin, GD Lowe, Haemostasis and Thrombosis Task Force of the British Committee for Standards in Haematology Guidelines on fibrinogen assays Br J Haematol 121 2003 396 404 (Pubitemid 36628330)
18. C Fenger-Eriksen, GW Moore, S Rangarajan, J Ingerslev, B Sørensen Fibrinogen estimates are influenced by methods of measurement and hemodilution with colloid plasma expanders Transfusion 50 2010 2571 2576
19. MT Ganter, CK Hofer Coagulation monitoring: current techniques and clinical use of viscoelastic point-of-care coagulation devices Anesth Analg 106 2008 1366 1375 (Pubitemid 351571062)
20. T Lang, A Bauters, SL Braun, B Pötzsch, KW von Pape, HJ Kolde et al. Multi-centre investigation on reference ranges for ROTEM thromboelastometry Blood Coagul Fibrinolysis 16 2005 301 310 (Pubitemid 40705054)
21. H Schöchl, U Nienaber, G Hofer, W Voelckel, C Jambor, G Scharbert et al. Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate Crit Care 14 2010 R55
22. H Schöchl, U Nienaber, M Maegele, G Hochleitner, F Primavesi, B Steitz et al. Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy Crit Care 15 2011 R83
23. K Görlinger, D Dirkmann, AA Hanke, M Kamler, E Kottenberg, M Thielmann et al. First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study Anesthesiology 115 2011 1179 1191
24. S Kozek-Langenecker, B Sørensen, JR Hess, DR Spahn Clinical effectiveness of fresh frozen plasma compared with fibrinogen concentrate: a systematic review Crit Care 15 2011 R239