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Volumn 11, Issue 1, 2013, Pages 19-28

Induction therapy for newly diagnosed multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; CLARITHROMYCIN; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; INTERFERON; LENALIDOMIDE; MELPHALAN; PAMIDRONIC ACID; PREDNISONE; THALIDOMIDE; VINCRISTINE;

EID: 84874601039     PISSN: 15401405     EISSN: 15401413     Source Type: Journal    
DOI: 10.6004/jnccn.2013.0005     Document Type: Review
Times cited : (9)

References (58)
  • 1
    • 0038509089 scopus 로고    scopus 로고
    • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: A report of the international myeloma working group
    • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol 2003;121:749-757.
    • (2003) Br J Haematol , vol.121 , pp. 749-757
  • 2
    • 79955559161 scopus 로고    scopus 로고
    • Smoldering multiple myeloma (SMM) at high-risk of progression to symptomatic disease: A phase III, randomized, multicenter trial based on lenalidomide-dexamethasone (Len-Dex) as induction therapy followed by maintenance therapy with len alone vs no treatment [abstract]
    • Abstract 1935
    • Mateos MV, Lopez-Corral L, Hernandez M, et al. Smoldering multiple myeloma (SMM) at high-risk of progression to symptomatic disease: a phase III, randomized, multicenter trial based on lenalidomide-dexamethasone (Len-Dex) as induction therapy followed by maintenance therapy with len alone vs no treatment [abstract]. Blood 2010;116:Abstract 1935.
    • (2010) Blood , vol.116
    • Mateos, M.V.1    Lopez-Corral, L.2    Hernandez, M.3
  • 3
    • 38649126166 scopus 로고    scopus 로고
    • Stem-cell transplantation for multiple myeloma in the era of novel drugs
    • Bensinger W. Stem-cell transplantation for multiple myeloma in the era of novel drugs. J Clin Oncol 2008;26:480-492.
    • (2008) J Clin Oncol , vol.26 , pp. 480-492
    • Bensinger, W.1
  • 4
    • 0034791513 scopus 로고    scopus 로고
    • Autologous stem cell transplantation in elderly multiple myeloma patients over the age of 70 years
    • Badros A, Barlogie B, Siegel E, et al. Autologous stem cell transplantation in elderly multiple myeloma patients over the age of 70 years. Br J Haematol 2001;114:600-607.
    • (2001) Br J Haematol , vol.114 , pp. 600-607
    • Badros, A.1    Barlogie, B.2    Siegel, E.3
  • 5
    • 70350091086 scopus 로고    scopus 로고
    • International myeloma working group (IMWG) consensus statement and guidelines regarding the current status of stem cell collection and high-dose therapy for multiple myeloma and the role of plerixafor (AMD 3100)
    • Giralt S, Stadtmauer EA, Harousseau JL, et al. International myeloma working group (IMWG) consensus statement and guidelines regarding the current status of stem cell collection and high-dose therapy for multiple myeloma and the role of plerixafor (AMD 3100). Leukemia 2009;23:1904-1912.
    • (2009) Leukemia , vol.23 , pp. 1904-1912
    • Giralt, S.1    Stadtmauer, E.A.2    Harousseau, J.L.3
  • 6
    • 79959398524 scopus 로고    scopus 로고
    • International myeloma working group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation
    • Cavo M, Rajkumar SV, Palumbo A, et al. International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation. Blood 2011;117:6063-6073.
    • (2011) Blood , vol.117 , pp. 6063-6073
    • Cavo, M.1    Rajkumar, S.V.2    Palumbo, A.3
  • 7
    • 78650303860 scopus 로고    scopus 로고
    • Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: A randomised phase 3 study
    • Cavo M, Tacchetti P, Patriarca F, et al. Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study. Lancet 2010;376:2075-2085.
    • (2010) Lancet , vol.376 , pp. 2075-2085
    • Cavo, M.1    Tacchetti, P.2    Patriarca, F.3
  • 8
    • 84865171981 scopus 로고    scopus 로고
    • Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: Results of the randomized phase III HOVON-65/GMMG-HD4 trial
    • Sonneveld P, Schmidt-Wolf IG, van der Holt B, et al. Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/GMMG-HD4 trial. J Clin Oncol 2012;30:2946-2955.
    • (2012) J Clin Oncol , vol.30 , pp. 2946-2955
    • Sonneveld, P.1    Schmidt-Wolf, I.G.2    Van Der Holt, B.3
  • 9
    • 73249146496 scopus 로고    scopus 로고
    • Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: An open-label randomised controlled trial
    • Rajkumar SV, Jacobus S, Callander NS, et al. Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial. Lancet Oncol 2010;11:29-37.
    • (2010) Lancet Oncol , vol.11 , pp. 29-37
    • Rajkumar, S.V.1    Jacobus, S.2    Callander, N.S.3
  • 10
    • 78049488759 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: Results of the IFM 2005-01 phase III trial
    • Harousseau JL, Attal M, Avet-Loiseau H, et al. Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial. J Clin Oncol 2010;28:4621-4629.
    • (2010) J Clin Oncol , vol.28 , pp. 4621-4629
    • Harousseau, J.L.1    Attal, M.2    Avet-Loiseau, H.3
  • 11
    • 33644831033 scopus 로고    scopus 로고
    • Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group
    • Rajkumar SV, Blood E, Vesole D, et al. Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol 2006;24:431-436.
    • (2006) J Clin Oncol , vol.24 , pp. 431-436
    • Rajkumar, S.V.1    Blood, E.2    Vesole, D.3
  • 12
    • 82155178738 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone versus reduced-dose bortezomib, thalidomide plus dexamethasone as induction treatment before autologous stem cell transplantation in newly diagnosed multiple myeloma
    • Moreau P, Avet-Loiseau H, Facon T, et al. Bortezomib plus dexamethasone versus reduced-dose bortezomib, thalidomide plus dexamethasone as induction treatment before autologous stem cell transplantation in newly diagnosed multiple myeloma. Blood 2011;118:5752-5758.
    • (2011) Blood , vol.118 , pp. 5752-5758
    • Moreau, P.1    Avet-Loiseau, H.2    Facon, T.3
  • 13
    • 75149140434 scopus 로고    scopus 로고
    • Phase 2 study of two sequential three-drug combinations containing bortezomib, cyclophosphamide and dexamethasone, followed by bortezomib, thalidomide and dexamethasone as frontline therapy for multiple myeloma
    • Bensinger WI, Jagannath S, Vescio R, et al. Phase 2 study of two sequential three-drug combinations containing bortezomib, cyclophosphamide and dexamethasone, followed by bortezomib, thalidomide and dexamethasone as frontline therapy for multiple myeloma. Br J Haematol 2010;148:562-568.
    • (2010) Br J Haematol , vol.148 , pp. 562-568
    • Bensinger, W.I.1    Jagannath, S.2    Vescio, R.3
  • 14
    • 77954618168 scopus 로고    scopus 로고
    • Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
    • Richardson PG, Weller E, Lonial S, et al. Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood 2010;116:679-686.
    • (2010) Blood , vol.116 , pp. 679-686
    • Richardson, P.G.1    Weller, E.2    Lonial, S.3
  • 15
    • 67650882695 scopus 로고    scopus 로고
    • Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: High response rates in a phase II clinical trial
    • Reeder CB, Reece DE, Kukreti V, et al. Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial. Leukemia 2009;23:1337-1341.
    • (2009) Leukemia , vol.23 , pp. 1337-1341
    • Reeder, C.B.1    Reece, D.E.2    Kukreti, V.3
  • 16
    • 76249096571 scopus 로고    scopus 로고
    • How i treat multiple myeloma in younger patients
    • Stewart AK, Richardson PG, San-Miguel JF. How I treat multiple myeloma in younger patients. Blood 2009;114:5436-5443.
    • (2009) Blood , vol.114 , pp. 5436-5443
    • Stewart, A.K.1    Richardson, P.G.2    San-Miguel, J.F.3
  • 17
    • 73349126431 scopus 로고    scopus 로고
    • Achievement of at least very good partial response is a simple and robust prognostic factor in patients with multiple myeloma treated with high-dose therapy: Long-term analysis of the IFM 99-02 and 99-04 Trials
    • Harousseau JL, Avet-Loiseau H, Attal M, et al. Achievement of at least very good partial response is a simple and robust prognostic factor in patients with multiple myeloma treated with high-dose therapy: long-term analysis of the IFM 99-02 and 99-04 Trials. J Clin Oncol 2009;27:5720-5726.
    • (2009) J Clin Oncol , vol.27 , pp. 5720-5726
    • Harousseau, J.L.1    Avet-Loiseau, H.2    Attal, M.3
  • 18
    • 79960695172 scopus 로고    scopus 로고
    • Long-term prognostic significance of response in multiple myeloma after stem cell transplantation
    • Martinez-Lopez J, Blade J, Mateos MV, et al. Long-term prognostic significance of response in multiple myeloma after stem cell transplantation. Blood 2011;118:529-534.
    • (2011) Blood , vol.118 , pp. 529-534
    • Martinez-Lopez, J.1    Blade, J.2    Mateos, M.V.3
  • 19
    • 80052272968 scopus 로고    scopus 로고
    • 2 and autologous transplantation (MEL200) in newly diagnosed multiple myeloma patients [abstract]
    • Abstract 3573
    • 2 and autologous transplantation (MEL200) in newly diagnosed multiple myeloma patients [abstract]. Blood 2010;116:Abstract 3573.
    • (2010) Blood , vol.116
    • Palumbo, A.1    Cavallo, F.2    Hardan, I.3
  • 20
    • 84874590205 scopus 로고    scopus 로고
    • Outcome with lenalidomide plus dexamethasone followed by early autologous stem cell transplantation in the ECOG E4A03 randomized clinical trial [abstract]
    • Abstract 38
    • diCapua Siegel DS, Jacobus S, Rajkumar SV, et al. Outcome with lenalidomide plus dexamethasone followed by early autologous stem cell transplantation in the ECOG E4A03 randomized clinical trial [abstract]. Blood 2010;116:Abstract 38.
    • (2010) Blood , vol.116
    • Dicapua Siegel, D.S.1    Jacobus, S.2    Rajkumar, S.V.3
  • 21
    • 79960661355 scopus 로고    scopus 로고
    • Frontline therapy with bortezomib, lenalidomide, and dexamethasone (VRD) induction followed by autologous stem cell transplantation, VRD consolidation and lenalidomide maintenance in newly diagnosed multiple myeloma patients: Primary results of the IFM 2008 phase II study [abstract]
    • Abstract 624
    • Roussel M, Avet-Loiseau H, Moreau P, et al. Frontline therapy with bortezomib, lenalidomide, and dexamethasone (VRD) induction followed by autologous stem cell transplantation, VRD consolidation and lenalidomide maintenance in newly diagnosed multiple myeloma patients: primary results of the IFM 2008 phase II study [abstract]. Blood 2010;116:Abstract 624.
    • (2010) Blood , vol.116
    • Roussel, M.1    Avet-Loiseau, H.2    Moreau, P.3
  • 22
    • 84865444078 scopus 로고    scopus 로고
    • Superiority of bortezomib, thalidomide and dexamethasone (VTD) as induction pre-transplantation therapy in multiple myeloma: A randomized phase III PETHEMA/GEM study
    • Rosinol L, Oriol A, Teruel AI, et al. Superiority of bortezomib, thalidomide and dexamethasone (VTD) as induction pre-transplantation therapy in multiple myeloma: a randomized phase III PETHEMA/GEM study. Blood 2012;120:1589-1596.
    • (2012) Blood , vol.120 , pp. 1589-1596
    • Rosinol, L.1    Oriol, A.2    Teruel, A.I.3
  • 23
    • 79955016800 scopus 로고    scopus 로고
    • Evidence-based mini-review: Treatment options for patients with relapsed/refractory myeloma previously treated with novel agents and high-dose chemotherapy and autologous stem-cell transplantation
    • Shah N, Lonial S. Evidence-based mini-review: treatment options for patients with relapsed/refractory myeloma previously treated with novel agents and high-dose chemotherapy and autologous stem-cell transplantation. Hematology Am Soc Hematol Educ Program 2010;2010:310-313.
    • (2010) Hematology Am Soc Hematol Educ Program , vol.2010 , pp. 310-313
    • Shah, N.1    Lonial, S.2
  • 24
    • 70350094381 scopus 로고    scopus 로고
    • International myeloma working group guidelines for the management of multiple myeloma patients ineligible for standard high-dose chemotherapy with autologous stem cell transplantation
    • Palumbo A, Sezer O, Kyle R, et al. International Myeloma Working Group guidelines for the management of multiple myeloma patients ineligible for standard high-dose chemotherapy with autologous stem cell transplantation. Leukemia 2009;23:1716-1730.
    • (2009) Leukemia , vol.23 , pp. 1716-1730
    • Palumbo, A.1    Sezer, O.2    Kyle, R.3
  • 25
    • 80051557449 scopus 로고    scopus 로고
    • Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation
    • Morgan GJ, Davies FE, Gregory WM, et al. Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation. Blood 2011;118:1231-1238.
    • (2011) Blood , vol.118 , pp. 1231-1238
    • Morgan, G.J.1    Davies, F.E.2    Gregory, W.M.3
  • 26
    • 65349142006 scopus 로고    scopus 로고
    • Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma
    • Ludwig H, Hajek R, Tothova E, et al. Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma. Blood 2009;113:3435-3442.
    • (2009) Blood , vol.113 , pp. 3435-3442
    • Ludwig, H.1    Hajek, R.2    Tothova, E.3
  • 27
    • 84860744403 scopus 로고    scopus 로고
    • Continuous lenalidomide treatment for newly diagnosed multiple myeloma
    • Palumbo A, Hajek R, Delforge M, et al. Continuous lenalidomide treatment for newly diagnosed multiple myeloma. N Engl J Med 2012;366:1759-1769.
    • (2012) N Engl J Med , vol.366 , pp. 1759-1769
    • Palumbo, A.1    Hajek, R.2    Delforge, M.3
  • 28
    • 50449086728 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    • San Miguel JF, Schlag R, Khuageva NK, et al. Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med 2008;359:906-917.
    • (2008) N Engl J Med , vol.359 , pp. 906-917
    • San Miguel, J.F.1    Schlag, R.2    Khuageva, N.K.3
  • 29
    • 84858791957 scopus 로고    scopus 로고
    • Continued overall survival benefit after 5 years' follow-up with bortezomib-melphalan-prednisone (VMP) versus melphalan-prednisone (MP) in patients with previously untreated multiple myeloma, and no increased risk of second primary malignancies: Final results of the phase 3 VISTA trial [abstract]
    • Abstract 476
    • San Miguel JF, Schlag R, Khuageva NK, et al. Continued overall survival benefit after 5 years' follow-up with bortezomib-melphalan-prednisone (VMP) versus melphalan-prednisone (MP) in patients with previously untreated multiple myeloma, and no increased risk of second primary malignancies: final results of the phase 3 VISTA trial [abstract]. Blood 2011;118:Abstract 476.
    • (2011) Blood , vol.118
    • San Miguel, J.F.1    Schlag, R.2    Khuageva, N.K.3
  • 30
    • 82155201722 scopus 로고    scopus 로고
    • Safety and efficacy of bortezomib-melphalan-prednisone-thalidomide followed by bortezomib-thalidomide maintenance (VMPT-VT) versus bortezomib-melphalan-prednisone (VMP) in untreated multiple myeloma patients with renal impairment
    • Morabito F, Gentile M, Mazzone C, et al. Safety and efficacy of bortezomib-melphalan-prednisone-thalidomide followed by bortezomib-thalidomide maintenance (VMPT-VT) versus bortezomib-melphalan-prednisone (VMP) in untreated multiple myeloma patients with renal impairment. Blood 2011;118:5759-5766.
    • (2011) Blood , vol.118 , pp. 5759-5766
    • Morabito, F.1    Gentile, M.2    Mazzone, C.3
  • 31
    • 77957344540 scopus 로고    scopus 로고
    • Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: A randomised trial
    • Mateos MV, Oriol A, Martinez-Lopez J, et al. Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: a randomised trial. Lancet Oncol 2010;11:934-941.
    • (2010) Lancet Oncol , vol.11 , pp. 934-941
    • Mateos, M.V.1    Oriol, A.2    Martinez-Lopez, J.3
  • 32
    • 79955461011 scopus 로고    scopus 로고
    • Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: A randomised, phase 3, non-inferiority study
    • Moreau P, Pylypenko H, Grosicki S, et al. Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study. Lancet Oncol 2011;12:431-440.
    • (2011) Lancet Oncol , vol.12 , pp. 431-440
    • Moreau, P.1    Pylypenko, H.2    Grosicki, S.3
  • 33
    • 84862696861 scopus 로고    scopus 로고
    • Efficacy and safety of three bortezomib-based combinations in elderly, newly diagnosed multiple myeloma patients: Results from all randomized patients in the community-based, phase 3b UPFRONT study [abstract]
    • Abstract 478
    • Niesvizky R, Flinn IW, Rifkin R, et al. Efficacy and safety of three bortezomib-based combinations in elderly, newly diagnosed multiple myeloma patients: results from all randomized patients in the community-based, phase 3b UPFRONT study [abstract]. Blood 2011;118:Abstract 478.
    • (2011) Blood , vol.118
    • Niesvizky, R.1    Flinn, I.W.2    Rifkin, R.3
  • 35
    • 84870760136 scopus 로고    scopus 로고
    • Survival outcomes of early autologous stem cell transplant (ASCT) followed by lenalidomide, bortezomib, and dexamethasone (RVD) maintenance in patients with high-risk multiple myeloma (MM) [abstract]
    • Abstract 8100
    • Kaufman J, Nooka A, Muppidi S, et al. Survival outcomes of early autologous stem cell transplant (ASCT) followed by lenalidomide, bortezomib, and dexamethasone (RVD) maintenance in patients with high-risk multiple myeloma (MM) [abstract]. J Clin Oncol 2012;30(Suppl):Abstract 8100.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Kaufman, J.1    Nooka, A.2    Muppidi, S.3
  • 36
    • 34249669340 scopus 로고    scopus 로고
    • Maintenance therapy in multiple myeloma
    • Mihelic R, Kaufman JL, Lonial S. Maintenance therapy in multiple myeloma. Leukemia 2007;21:1150-1157.
    • (2007) Leukemia , vol.21 , pp. 1150-1157
    • Mihelic, R.1    Kaufman, J.L.2    Lonial, S.3
  • 37
    • 84860741191 scopus 로고    scopus 로고
    • Lenalidomide after stem-cell transplantation for multiple myeloma
    • McCarthy PL, Owzar K, Hofmeister CC, et al. Lenalidomide after stem-cell transplantation for multiple myeloma. N Engl J Med 2012;366:1770-1781.
    • (2012) N Engl J Med , vol.366 , pp. 1770-1781
    • McCarthy, P.L.1    Owzar, K.2    Hofmeister, C.C.3
  • 38
    • 84860709392 scopus 로고    scopus 로고
    • Lenalidomide maintenance after stem-cell transplantation for multiple myeloma
    • Attal M, Lauwers-Cances V, Marit G, et al. Lenalidomide maintenance after stem-cell transplantation for multiple myeloma. N Engl J Med 2012;366:1782-1791.
    • (2012) N Engl J Med , vol.366 , pp. 1782-1791
    • Attal, M.1    Lauwers-Cances, V.2    Marit, G.3
  • 39
    • 78650623731 scopus 로고    scopus 로고
    • International Myeloma Working Group consensus statement regarding the current status of allogeneic stem-cell transplantation for multiple myeloma
    • Lokhorst H, Einsele H, Vesole D, et al. International Myeloma Working Group consensus statement regarding the current status of allogeneic stem-cell transplantation for multiple myeloma. J Clin Oncol 2010;28:4521-4530.
    • (2010) J Clin Oncol , vol.28 , pp. 4521-4530
    • Lokhorst, H.1    Einsele, H.2    Vesole, D.3
  • 40
    • 80051642093 scopus 로고    scopus 로고
    • Tandem autologous/reduced-intensity conditioning allogeneic stem-cell transplantation versus autologous transplantation in myeloma: Long-term follow-up
    • Bjorkstrand B, Iacobelli S, Hegenbart U, et al. Tandem autologous/reduced-intensity conditioning allogeneic stem-cell transplantation versus autologous transplantation in myeloma: long-term follow-up. J Clin Oncol 2011;29:3016-3022.
    • (2011) J Clin Oncol , vol.29 , pp. 3016-3022
    • Bjorkstrand, B.1    Iacobelli, S.2    Hegenbart, U.3
  • 41
    • 33947197286 scopus 로고    scopus 로고
    • A comparison of allografting with autografting for newly diagnosed myeloma
    • Bruno B, Rotta M, Patriarca F, et al. A comparison of allografting with autografting for newly diagnosed myeloma. N Engl J Med 2007;356:1110-1120.
    • (2007) N Engl J Med , vol.356 , pp. 1110-1120
    • Bruno, B.1    Rotta, M.2    Patriarca, F.3
  • 42
    • 82555179157 scopus 로고    scopus 로고
    • Autologous haemopoietic stem-cell transplantation followed by allogeneic or autologous haemopoietic stem-cell transplantation in patients with multiple myeloma (BMT CTN 0102): A phase 3 biological assignment trial
    • Krishnan A, Pasquini MC, Logan B, et al. Autologous haemopoietic stem-cell transplantation followed by allogeneic or autologous haemopoietic stem-cell transplantation in patients with multiple myeloma (BMT CTN 0102): a phase 3 biological assignment trial. Lancet Oncol 2011;12:1195-1203.
    • (2011) Lancet Oncol , vol.12 , pp. 1195-1203
    • Krishnan, A.1    Pasquini, M.C.2    Logan, B.3
  • 43
    • 79956157909 scopus 로고    scopus 로고
    • Tandem autologous stem cell transplants (auto-auto) with or without maintenance therapy versus single autologous transplant followed by HLA-matched sibling non-myeloablative allogeneic stem cell transplant (auto-allo) for patients (pts) with high risk (HR) multiple myeloma (MM): Results from the Blood and Marrow Transplant Clinical Trials Network (BMT-CTN) 0102 trial [abstract]
    • Abstract 526
    • Stadtmauer EA, Krishnan A, Pasquini MC, et al. Tandem autologous stem cell transplants (auto-auto) with or without maintenance therapy versus single autologous transplant followed by HLA-matched sibling non-myeloablative allogeneic stem cell transplant (auto-allo) for patients (pts) with high risk (HR) multiple myeloma (MM): results from the Blood and Marrow Transplant Clinical Trials Network (BMT-CTN) 0102 trial [abstract]. Blood 2010;116:Abstract 526.
    • (2010) Blood , vol.116
    • Stadtmauer, E.A.1    Krishnan, A.2    Pasquini, M.C.3
  • 44
    • 84863520725 scopus 로고    scopus 로고
    • Donor versus no-donor comparison of newly diagnosed myeloma patients included in the HOVON-50 multiple myeloma study
    • Lokhorst HM, van der Holt B, Cornelissen JJ, et al. Donor versus no-donor comparison of newly diagnosed myeloma patients included in the HOVON-50 multiple myeloma study. Blood 2012;119:6219-6225.
    • (2012) Blood , vol.119 , pp. 6219-6225
    • Lokhorst, H.M.1    Van Der Holt, B.2    Cornelissen, J.J.3
  • 45
    • 84863525019 scopus 로고    scopus 로고
    • Death of frontline allo-SCT in myeloma
    • Moreau P. Death of frontline allo-SCT in myeloma. Blood 2012;119:6178-6179.
    • (2012) Blood , vol.119 , pp. 6178-6179
    • Moreau, P.1
  • 46
    • 77951453409 scopus 로고    scopus 로고
    • Once- versus twice-weekly bortezomib induction therapy with CyBorD in newly diagnosed multiple myeloma
    • Reeder CB, Reece DE, Kukreti V, et al. Once- versus twice-weekly bortezomib induction therapy with CyBorD in newly diagnosed multiple myeloma. Blood 2010;115:3416-3417.
    • (2010) Blood , vol.115 , pp. 3416-3417
    • Reeder, C.B.1    Reece, D.E.2    Kukreti, V.3
  • 47
    • 79960666079 scopus 로고    scopus 로고
    • Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: A phase 1/2 Multiple Myeloma Research Consortium trial
    • Jakubowiak AJ, Griffith KA, Reece DE, et al. Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: a phase 1/2 Multiple Myeloma Research Consortium trial. Blood 2011;118:535-543.
    • (2011) Blood , vol.118 , pp. 535-543
    • Jakubowiak, A.J.1    Griffith, K.A.2    Reece, D.E.3
  • 48
    • 38949216066 scopus 로고    scopus 로고
    • BiRD (Biaxin [clarithromycin]/Revlimid [lenalidomide]/dexamethasone) combination therapy results in high complete- and overall-response rates in treatment-naive symptomatic multiple myeloma
    • Niesvizky R, Jayabalan DS, Christos PJ, et al. BiRD (Biaxin [clarithromycin]/Revlimid [lenalidomide]/dexamethasone) combination therapy results in high complete- and overall-response rates in treatment-naive symptomatic multiple myeloma. Blood 2008;111:1101-1109.
    • (2008) Blood , vol.111 , pp. 1101-1109
    • Niesvizky, R.1    Jayabalan, D.S.2    Christos, P.J.3
  • 49
    • 77649092410 scopus 로고    scopus 로고
    • Phase II trial of combination therapy with bortezomib, pegylated liposomal doxorubicin, and dexamethasone in patients with newly diagnosed myeloma
    • Jakubowiak AJ, Kendall T, Al-Zoubi A, et al. Phase II trial of combination therapy with bortezomib, pegylated liposomal doxorubicin, and dexamethasone in patients with newly diagnosed myeloma. J Clin Oncol 2009;27:5015-5022.
    • (2009) J Clin Oncol , vol.27 , pp. 5015-5022
    • Jakubowiak, A.J.1    Kendall, T.2    Al-Zoubi, A.3
  • 50
    • 84865333050 scopus 로고    scopus 로고
    • A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma
    • Jakubowiak AJ, Dytfeld D, Griffith KA, et al. A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma. Blood 2012;120:1801-1809.
    • (2012) Blood , vol.120 , pp. 1801-1809
    • Jakubowiak, A.J.1    Dytfeld, D.2    Griffith, K.A.3
  • 51
    • 78649686431 scopus 로고    scopus 로고
    • Lenalidomide and high-dose dexamethasone compared with dexamethasone as initial therapy for multiple myeloma: A randomized Southwest Oncology Group trial (S0232)
    • Zonder JA, Crowley J, Hussein MA, et al. Lenalidomide and high-dose dexamethasone compared with dexamethasone as initial therapy for multiple myeloma: a randomized Southwest Oncology Group trial (S0232). Blood 2010;116:5838-5841.
    • (2010) Blood , vol.116 , pp. 5838-5841
    • Zonder, J.A.1    Crowley, J.2    Hussein, M.A.3
  • 52
    • 78650349052 scopus 로고    scopus 로고
    • Outcome of elderly patients 70 years and older with newly diagnosed myeloma in the ECOG randomized trial of lenalidomide/high-dose dexamethasone (RD) versus lenalidomide/low-dose dexamethasone (Rd) [abstract]
    • Abstract 0370
    • Jacobus S, Callander N, Siegel D, et al. Outcome of elderly patients 70 years and older with newly diagnosed myeloma in the ECOG randomized trial of lenalidomide/high-dose dexamethasone (RD) versus lenalidomide/low-dose dexamethasone (Rd) [abstract]. Haematologica 2010;95(Suppl 2):149. Abstract 0370.
    • (2010) Haematologica , vol.95 , Issue.SUPPL. 2 , pp. 149
    • Jacobus, S.1    Callander, N.2    Siegel, D.3
  • 53
    • 43749117945 scopus 로고    scopus 로고
    • Multicenter, randomized, double-blind, placebo-controlled study of thalidomide plus dexamethasone compared with dexamethasone as initial therapy for newly diagnosed multiple myeloma
    • Rajkumar SV, Rosinol L, Hussein M, et al. Multicenter, randomized, double-blind, placebo-controlled study of thalidomide plus dexamethasone compared with dexamethasone as initial therapy for newly diagnosed multiple myeloma. J Clin Oncol 2008;26:2171-2177.
    • (2008) J Clin Oncol , vol.26 , pp. 2171-2177
    • Rajkumar, S.V.1    Rosinol, L.2    Hussein, M.3
  • 54
    • 54049135250 scopus 로고    scopus 로고
    • Oral melphalan, prednisone, and thalidomide in elderly patients with multiple myeloma: Updated results of a randomized, controlled trial
    • Palumbo A, Bringhen S, Liberati AM, et al. Oral melphalan, prednisone, and thalidomide in elderly patients with multiple myeloma: updated results of a randomized, controlled trial. Blood 2008;112:3107-3114.
    • (2008) Blood , vol.112 , pp. 3107-3114
    • Palumbo, A.1    Bringhen, S.2    Liberati, A.M.3
  • 55
    • 34848833957 scopus 로고    scopus 로고
    • Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): A randomised trial
    • Facon T, Mary JY, Hulin C, et al. Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial. Lancet 2007;370:1209-1218.
    • (2007) Lancet , vol.370 , pp. 1209-1218
    • Facon, T.1    Mary, J.Y.2    Hulin, C.3
  • 56
    • 77956599686 scopus 로고    scopus 로고
    • Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma
    • Waage A, Gimsing P, Fayers P, et al. Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma. Blood 2010;116:1405-1412.
    • (2010) Blood , vol.116 , pp. 1405-1412
    • Waage, A.1    Gimsing, P.2    Fayers, P.3
  • 57
    • 77955495783 scopus 로고    scopus 로고
    • Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: The HOVON 49 Study
    • Wijermans P, Schaafsma M, Termorshuizen F, et al. Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: the HOVON 49 Study. J Clin Oncol 2010;28:3160-3166.
    • (2010) J Clin Oncol , vol.28 , pp. 3160-3166
    • Wijermans, P.1    Schaafsma, M.2    Termorshuizen, F.3
  • 58
    • 68949137225 scopus 로고    scopus 로고
    • Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial
    • Hulin C, Facon T, Rodon P, et al. Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial. J Clin Oncol 2009;27:3664-3670.
    • (2009) J Clin Oncol , vol.27 , pp. 3664-3670
    • Hulin, C.1    Facon, T.2    Rodon, P.3


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