Limbic system surgery for treatment-refractory obsessive-compulsive disorder: A prospective long-term follow-up of 64 patients

Journal of Neurosurgery

Volumn 118, Issue 3, 2013, Pages 491-497

  Sheth, Sameer A ^a   Neal, Jonathan ^a   Tangherlini, Frances ^a   Mian, Matthew K ^a,b   Gentil, Andre ^c   Cosgrove, G Rees ^d   Eskandar, Emad N ^a,b   Dougherty, Darin D ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d BROWN UNIVERSITY   (United States)

Author keywords

Cingulotomy; Depression; Functional neurosurgery; Obsessive compulsive disorder; Psychiatric neurosurgery

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BRAIN SURGERY; CINGULECTOMY; CLINICAL EFFECTIVENESS; COMORBIDITY; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OBSESSIVE COMPULSIVE DISORDER; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; REOPERATION; SUBCAUDATE TRACTOTOMY; TREATMENT RESPONSE;

ADOLESCENT; ADULT; AGED; FEMALE; FOLLOW-UP STUDIES; HUMANS; LIMBIC SYSTEM; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OBSESSIVE-COMPULSIVE DISORDER; PROSPECTIVE STUDIES; PSYCHIATRIC STATUS RATING SCALES; PSYCHOSURGERY; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 84874594942     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2012.11.JNS12389     Document Type: Article

References (25)

1. Alexander GE, Crutcher MD: Functional architecture of basal ganglia circuits: Neural substrates of parallel processing. Trends Neurosci 13:266-271, 1990
2. Alexander GE, DeLong MR, Strick PL: Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9:357-381, 1986
3. Baer L, Rauch SL, Ballantine HT Jr, Martuza R, Cosgrove R, Cassem E, et al: Cingulotomy for intractable obsessivecompulsive disorder. Prospective long-term follow-up of 18 patients. Arch Gen Psychiatry 52:384-392, 1995
4. Ballantine HT Jr, Cassidy WL, Flanagan NB, Marino R Jr: Stereotaxic anterior cingulotomy for neuropsychiatric illness and intractable pain. J Neurosurg 26:488-495, 1967
5. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J: An inventory for measuring depression. Arch Gen Psychiatry 4: 561-571, 1961
6. Dougherty DD, Baer L, Cosgrove GR, Cassem EH, Price BH, Nierenberg AA, et al: Prospective long-term follow-up of 44 patients who received cingulotomy for treatment-refractory obsessive-compulsive disorder. Am J Psychiatry 159:269-275, 2002
7. Goodman WK, Foote KD, Greenberg BD, Ricciuti N, Bauer R, Ward H, et al: Deep brain stimulation for intractable obsessive compulsive disorder: Pilot study using a blinded, staggered-onset design. Biol Psychiatry 67:535-542, 2010
8. Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, et al: The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. Arch Gen Psychiatry 46:1006-1011, 1989
9. Greenberg BD, Gabriels LA, Malone DA Jr, Rezai AR, Friehs GM, Okun MS, et al: Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive-compulsive disorder: Worldwide experience. Mol Psychiatry 15:64-79, 2010
10. Greenberg BD, Malone DA, Friehs GM, Rezai AR, Kubu CS, Malloy PF, et al: Three-year outcomes in deep brain stimulation for highly resistant obsessive-compulsive disorder. Neuropsychopharmacology 31:2384-2393, 2006
11. Greenberg BD, Rauch SL, Haber SN: Invasive circuitry-based neurotherapeutics: Stereotactic ablation and deep brain stimulation for OCD. Neuropsychopharmacology 35:317-336, 2010
12. Jenike MA, Baer L, Ballantine T, Martuza RL, Tynes S, Giriunas I, et al: Cingulotomy for refractory obsessive-compulsive disorder. A long-term follow-up of 33 patients. Arch Gen Psychiatry 48:548-555, 1991
13. Kelly D, Richardson A, Mitchell-Heggs N: Stereotactic limbic leucotomy: Neurophysiological aspects and operative technique. Br J Psychiatry 123:133-140, 1973
14. Kelly D, Richardson A, Mitchell-Heggs N, Greenup J, Chen C, Hafner RJ: Stereotactic limbic leucotomy: A preliminary report on forty patients. Br J Psychiatry 123:141-148, 1973
15. Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE: Prevalence, severity, and comorbidity of 12-month DSMIV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 62:617-627, 2005 (Erratum in Arch Gen Psychiatry 62:709, 2005)
16. Knight G: Stereotactic tractotomy in the surgical treatment of mental illness. J Neurol Neurosurg Psychiatry 28:304-310, 1965
17. Leksell L: The stereotaxic method and radiosurgery of the brain. Acta Chir Scand 102:316-319, 1951
18. Mian MK, Campos M, Sheth SA, Eskandar EN: Deep brain stimulation for obsessive-compulsive disorder: Past, present, and future. Neurosurg Focus 29(2):E10, 2010
19. Nuttin B, Cosyns P, Demeulemeester H, Gybels J, Meyerson B: Electrical stimulation in anterior limbs of internal capsules in patients with obsessive-compulsive disorder. Lancet 354:1526, 1999 (Letter)
20. Nuttin BJ, Gabriëls LA, Cosyns PR, Meyerson BA, Andréewitch S, Sunaert SG, et al: Long-term electrical capsular stimulation in patients with obsessive-compulsive disorder. Neurosurgery 52:1263-1274, 2003
21. Pallanti S, Quercioli L: Treatment-refractory obsessive-compulsive disorder: Methodological issues, operational definitions and therapeutic lines. Prog Neuropsychopharmacol Biol Psychiatry 30:400-412, 2006
22. Rasmussen SA, Eisen JL: The epidemiology and clinical features of obsessive compulsive disorder. Psychiatr Clin North Am 15:743-758, 1992
23. Shields DC, Asaad W, Eskandar EN, Jain FA, Cosgrove GR, Flaherty AW, et al: Prospective assessment of stereotactic ablative surgery for intractable major depression. Biol Psychiatry 64:449-454, 2008
24. Spiegel EA, Wycis HT, Marks M, Lee AJ: Stereotaxic apparatus for operations on the human brain. Science 106:349-350, 1947
25. Talairach J, Hécaen H, David M: Lobotomie préfrontal limitée par électrocoagulation des fibres thalamo-frontales à leur émergence du bras antérieur de la capsule interne. Rev Neurol 83:59, 1949