Directed molecular evolution reveals gaussia luciferase variants with enhanced light output stability

Analytical Chemistry

Volumn 85, Issue 5, 2013, Pages 3006-3012

  Degeling, M Hannah ^a,b,c   Bovenberg, M Sarah S ^a,b,c   Lewandrowski, Grant K ^a,b   De Gooijer, Mark C ^a,b,d   Vleggeert Lankamp, Carmen L A ^c   Tannous, Marie ^e   Maguire, Casey A ^a,b   Tannous, Bakhos A ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^e NOTRE DAME UNIVERSITY   (Lebanon)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PROCESS; BLUE LIGHT; CURRENT LIMITATION; EMISSION SPECTRUMS; HIGH-THROUGHPUT; IN-VIVO; LIGHT EMISSION PEAKS; LIGHT OUTPUT; MAMMALIAN CELLS; MAMMALIAN TISSUES; MOLECULAR EVOLUTION; REACTION CHARACTERISTICS;

EMISSION SPECTROSCOPY; LIGHT EMISSION; MAMMALS; MOLECULAR BIOLOGY; PHOSPHORESCENCE; TISSUE;

BIOLUMINESCENCE;

LUCIFERASE;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DIRECTED MOLECULAR EVOLUTION; GENETICS; LIGHT; LUMINESCENCE; METABOLISM; MOLECULAR GENETICS; MUTATION;

AMINO ACID SEQUENCE; DIRECTED MOLECULAR EVOLUTION; LIGHT; LUCIFERASES; LUMINESCENT MEASUREMENTS; MOLECULAR SEQUENCE DATA; MUTATION;

EID: 84874590715     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac4003134     Document Type: Article

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