Variable Stromal Periductular Expression of CD34 and Smooth Muscle Actin (SMA) in Intraductal Carcinoma of the Breast

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Catteau, Xavier ^a   Simon, Philippe ^b   Vanhaeverbeek, Michel ^c   Noël, Jean Christophe ^b  

^a INSTITUTE OF PATHOLOGY AND GENETICS   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c Centre Hospitalier Universitaire de Charleroi   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; SMOOTH MUSCLE ACTIN;

ARTICLE; BREAST; BREAST CARCINOMA; CANCER GRADING; CANCER INVASION; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRADUCTAL CARCINOMA; MYOFIBROBLAST; NECROSIS; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; STAINING;

ACTINS; ANTIGENS, CD34; BREAST NEOPLASMS; CARCINOMA IN SITU; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CASE-CONTROL STUDIES; FEMALE; GENE EXPRESSION; HUMANS; MYOFIBROBLASTS; NECROSIS; NEOPLASM GRADING; NEOPLASM INVASIVENESS; STROMAL CELLS;

EID: 84874559729     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057773     Document Type: Article

References (27)

1. Howlett AR, Bissell MJ, (1993) The influence of tissue microenvironment (stroma and extracellular matrix) on the development and function of mammary epithelium. Epithelial Cell Biol 2: 79-89.
2. Bissell MJ, Kenny PA, Radisky DC, (2005) Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes. Cold Spring Harb Symp Quant Biol 70: 343-356.
3. Weinberg R, Mihich E, (2006) Eighteenth annual pezcoller symposium: tumor microenvironment and heterotypic interactions. Cancer Res 66: 11550-11553.
4. Chesney J, Bacher M, Bender A, Bucala R, (1997) The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ. Proc Natl Acad Sci U S A 94: 6307-6312.
5. Wessel C, Westhoff CC, Nowak K, Moll I, Barth PJ, (2008) CD34(+) fibrocytes in melanocytic nevi and malignant melanomas of the skin. Virchows Arch 453: 485-489.
6. Barth PJ, Schenck zu Schweinsberg T, Ramaswamy A, Moll R, (2004) CD34+ fibrocytes, alpha-smooth muscle antigen-positive myofibroblasts, and CD117 expression in the stroma of invasive squamous cell carcinomas of the oral cavity, pharynx, and larynx. Virchows Arch 444: 231-234.
7. Barth PJ, Moll R, Ramaswamy A, (2005) Stromal remodeling and SPARC (secreted protein acid rich in cysteine) expression in invasive ductal carcinomas of the breast. Virchows Arch 446: 532-536.
8. Barth PJ, Ebrahimsade S, Ramaswamy A, Moll R, (2002) CD34+ fibrocytes in invasive ductal carcinoma, ductal carcinoma in situ, and benign breast lesions. Virchows Arch 440: 298-303.
9. Cimpean AM, Raica M, Narita D, (2005) Diagnostic significance of the immunoexpression of CD34 and smooth muscle cell actin in benign and malignant tumors of the breast. Rom J Morphol Embryol 46: 123-129.
10. Chauhan H, Abraham A, Phillips JR, Pringle JH, Walker RA, et al. (2003) There is more than one kind of myofibroblast: analysis of CD34 expression in benign, in situ, and invasive breast lesions. J Clin Pathol 56: 271-276.
11. Tlsty TD, Hein PW, (2001) Know thy neighbor: stromal cells can contribute oncogenic signals. Curr Opin Genet Dev 11: 54-59.
12. Moore T, Lee AH, (2001) Expression of CD34 and bcl-2 in phyllodes tumours, fibroadenomas and spindle cell lesions of the breast. Histopathology 38: 62-67.
13. Yamazaki K, Eyden BP, (1995) Ultrastructural and immunohistochemical observations on intralobular fibroblasts of human breast, with observations on the CD34 antigen. J Submicrosc Cytol Pathol 27: 309-323.
14. Bucala R, Spiegel LA, Chesney J, Hogan M, Cerami A, (1994) Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol Med 1: 71-81.
15. Rubin R (2008) Rubin's pathology: clinicopathologic foundations of medicine. 5th edition. Philadelphia: Lippincott Williams & Wilkins.
16. Catteau X, Simon P, Noel JC, (2012) Predictors of invasive breast cancer in mammographically detected microcalcification in patients with a core biopsy diagnosis of flat epithelial atypia, atypical ductal hyperplasia or ductal carcinoma in situ and recommendations for a selective approach to sentinel lymph node biopsy. Pathol Res Pract 208: 217-220.
17. Schwartz GF, Giuliano AE, Veronesi U, (2002) Consensus Conference Committee, Proceedings of the consensus conference on the role of sentinel lymph node biopsy in carcinoma of the breast April 19-22, 2001, Philadelphia, Pennsylvania. Cancer 94: 2542-2551.
18. Yen TW, Hunt KK, Ross MI, Mirza NQ, Babiera GV, et al. (2005) Predictors of invasive breast cancer in patients with an initial diagnosis of ductal carcinoma in situ: a guide to selective use of sentinel lymph node biopsy in management of ductal carcinoma in situ. J. Am. Coll. Surg 200: 516-526.
19. Liang X, Huuskonen J, Hajivandi M, Manzanedo R, Predki P, et al. (2009) Identification and quantification of proteins differentially secreted by a pair of normal and malignant breast-cancer cell lines. Proteomics 9: 182-193.
20. Valenti MT, Azzarello G, Balducci E, Sartore S, Sandri M, et al. (2001) Conditioned medium from MCF-7 cell line induces myofibroblast differentiation, decreased cell proliferation, and increased apoptosis in cultured normal fibroblasts but not in fibroblasts from malignant breast tissue. Histochem J 33: 499-509.
21. Abe R, Donnelly SC, Peng T, Bucala R, Metz CN, (2001) Peripheral blood fibrocytes: differentiation pathway and migration to wound sites. J Immunol 166: 7556-7562.
22. Espana EM, Kawakita T, Liu CY, Tseng SC, (2004) CD-34 expression by cultured human keratocytes is downregulated during myofibroblast differentiation induced by TGF-beta1. Invest Ophthalmol Vis Sci 45: 2985-2991.
23. Sircar K, Hewlett BR, Huizinga JD, Chorneyko K, Berezin I, et al. (1999) Interstitial cells of Cajal as precursors of gastrointestinal stromal tumors. Am J Surg Pathol 23: 377-389.
24. Suster S, Fisher C, (1997) Immunoreactivity for the human hematopoietic progenitor cell antigen (CD34) in lipomatous tumors. Am J Surg Pathol 21: 195-200.
25. Humphreys TR, Monteiro MR, Murphy GF, (2000) Mast cells and dendritic cells in basal cell carcinoma stroma. Dermatol Surg 26: 200-203.
26. Satish L, Gallo PH, Baratz ME, Johnson S, Kathju S, et al. (2011) Reversal of TGF-beta1 stimulation of alpha-smooth muscle actin and extracellular matrix components by cyclic AMP in Dupuytren's-derived fibroblasts. BMC Musculoskelet Disord 12: 113.
27. Lagios MD, (1995) Heterogeneity of duct carcinoma in situ (DCIS): relationship of grade and subtype analysis to local recurrence and risk of invasive transformation. Cancer Lett 90: 97-102.