Immunoreactivity for the human hematopoietic progenitor cell antigen (CD34) in lipomatous tumors

American Journal of Surgical Pathology

Volumn 21, Issue 2, 1997, Pages 195-200

  Suster, Saul ^a,c   Fisher, Cyril ^b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

CD34; Interstitial dendritic cells; Lipomatous neoplasms; Liposarcoma; Spindle cell lipoma

Indexed keywords

CD34 ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; DENDRITIC CELL; HEMATOPOIETIC CELL; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; LIPOMA; LIPOSARCOMA; SPINDLE CELL; STEM CELL; VASCULAR ENDOTHELIUM;

ANTIGENS, CD34; DIAGNOSIS, DIFFERENTIAL; ENDOTHELIUM, VASCULAR; HUMANS; IMMUNOHISTOCHEMISTRY; LIPOMA; LIPOSARCOMA; NEOPLASMS, ADIPOSE TISSUE; VIMENTIN;

EID: 0031057616     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199702000-00009     Document Type: Article

References (29)

1. Aiba S, Tabata N, Ishii H, et al. Dermatofibrosarcoma protuberans is a unique fibrohistiocytic tumor expressing CD34. Br J Cancer 1992;127:79-84.
2. Andrews RG, Singer JW, Bernstein ID. Monoclonal antibody 12-8 recognizes a 115-kD molecule present on both unipotent and multipotent hematopoietic colony-forming cells and their precursors. Blood 1986;67:842-5.
3. Arber DA, Kandalaft PL, Mehta P, Battifora H. Vimentin negative epithelioid sarcoma: the value of an immunohistochemical panel that includes CD34. Am J Sarg Pathol 1993;17:302-7.
4. Brathwaite C, Suster S. Dermatofibrosarcoma protuberans: a critical reappraisal of the role of immunohistochemical stains for diagnosis. Appl Immunohistochem 1994;2:36-41.
5. Civin CI, Strauss LC, Brovall C, Fackler MJ, Schwartz JF, Shaper JH. Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells. J Immunol 1984;133:157-65.
6. Cohen PR, Rapini RP, Farhood A. Expression of the human hematopoietic progenitor cell antigen CD34 in vascular and spindle cell tumors. J Cutan Pathol 1993;20:15-20.
7. Dei Tos AP, Seregard S, Calonje E, Chan JKC, Fletcher CDM. Giant cell angiofibroma: a distinctive orbital tumor in adults. Am J Surg Pathol 1995;19:1286-93.
8. Evans LH. Liposarcoma: a study of 55 cases with a reassessment of its classification. Am J Surg Pathol 1979;3:507-23.
9. Fina L, Molgaard HV, Robertson D, et al. Expression of the CD34 gene in vascular endothelial cells. Blood 1990;75:2417-26.
10. Hashimoto H, Daimaru Y, Tsuneyoshi M, Enjoji M. Soft tissue sarcoma with additional anaplastic components: a clinicopathologic and immunohistochemical study of 27 cases. Cancer 1990;66: 1578-89.
11. Maggio P, Szumigala J, Brooks JJ. CD34 positive spindle cell lipoma: are some cases incipient solitary fibrous tumors? [Abstract]. Mol Pathol 1996;9:10A.
12. McCormick D, Mentzel T, Beham A, Fletcher CDM. Dedifferentiated liposarcoma: clinicopathologic analysis of 32 cases suggesting a better prognostic subgroup among pleomorphic sarcomas. Am J Surg Pathol 1994;18:1213-23.
13. Miettinen M, Lindenmayer AE, Chaubal A. Endothelial cell markers CD31, CD34, and BNH9 antibody to H- and Y- antigens: evaluation of their specificity and sensitivity in the diagnosis of vascular tumors and comparison with von Willebrand factor. Mod Pathol 1994;7:82-9.
14. Mikhael AI, Bacchi CE, Zarbo RJ, Ma CK, Gown AM. CD34 expression in stromal tumors of the gastrointestinal tract. Appl Immunohistochem 1994;2:89-93.
15. Montgomery EA, Meis JM, Mitchell MS, Enzinger FM. Atypical decubital fibroplasia: a distinctive fibroblastic pseudotumor occurring in debilitated patients. Am J Surg Pathol 1992;16:708-15.
16. Moran CA, Suster S, Koss MN. The spectrum of histologic growth patterns in benign and malignant fibrous tumors of the pleura. Semin Diagn Pathol 1992;9:169-80.
17. Nickoloff BJ. The human progenitor cell antigen (CD34) is located on endothelial cells, dermal dendritic cells, and perifollicular cells in formalin-fixed normal skin, and on proliferating endothelial cells and stromal spindle shaped cells in Kaposi's sarcoma. Arch Dermatol 1991;127:523-9.
18. Ramani P, Bradley NJ, Fletcher CDM. QBEND/10, a new monoclonal antibody to endothelium: assessment of its diagnostic utility in paraffin sections. Hisiopathology 1990;17:237-42.
19. Regezi JA ,Nickoloff BJ, Headington JT. Oral submucosal dendrocytes: factor XIIIa+ and CD34+ dendritic cell populations in normal tissues and fibrovascular lesions. J Cutan Pathol 1992;19: 398-406.
20. Renshaw AA, Pinkus GS, Corson JM. CD34 and AE1/AE3: diagnostic discriminants in the distinction of solitary fibrous tumor of the pleura from sarcomatoid mesothelioma. Appl Immunohistochem 1994;2:94-102.
21. Sankey EA, More L, Dhillon AP, QBEnd/10: a new immunostain for the routine diagnosis of Kaposi's sarcoma. J Pathol 1990;161: 267-71.
22. Schlingemann RO, Rietveld FJ, de Waal RM, et al. Leukocyte antigen CD34 is expressed by a subset of cultured endothelial cells and on endothelial abluminal microprocesses in the tumor stroma. Lab Invest 1990;62:690-6.
23. Suster S, Nascimento AG, Miettinen M, Sickel JZ, Moran CA. Solitary fibrous tumors of soft tissue: a clinicopathologic and immunohistochemical study of 12 cases. Am J Surg Pathol 1995;19: 1257-66.
24. Suster S, Wong T-Y. On the discriminatory value of anti-HPCA-1 (CD34) in the differential diagnosis of benign and malignant cutaneous vascular proliferations. Am J Dermatopathol 1994;16: 355-63.
25. Traweek ST, Kandalaft PL, Mehta P, Battifora H. The human hematopoietic progenitor cell antigen (CD34) in vascular neoplasia. Am J Clin Pathol 1991;96:25-31.
26. Van de Rijn M, Lombard CM, Rouse RV. Expression of CD34 by solitary fibrous tumors of the pleura, mediastinum and lung. Am J Surg Pathol 1994;18:814-20.
27. Van de Rijn M, Rouse RV. CD34: a review. Appl Immunohistochem 1994;2:71-80.
28. Weiss SW, Nickoloff BJ. CD34 is expressed by a distinct population of peripheral nerve, nerve sheath tumors, and related lesions. Am J Surg Pathol 1993;17:1039-45.
29. Westra WH, Gerald WL, Rosai J. Solitary fibrous tumor: consistent CD34 immunoreactivity and occurrence in the orbit. Am J Surg Pathol 1994;18:992-8.