HIV Prevention in Care and Treatment Settings: Baseline Risk Behaviors among HIV Patients in Kenya, Namibia, and Tanzania

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Kidder, Daniel P ^a   Bachanas, Pam ^a   Medley, Amy ^a   Pals, Sherri ^a   Nuwagaba Biribonwoha, Harriet ^b   Ackers, Marta ^c   Howard, Andrea ^b   DeLuca, Nick ^c   Mbatia, Redempta ^d   Sheriff, Muhsin ^e   Arthur, Gilly ^c   Katuta, Frieda ^f   Cherutich, Peter ^g   Somi, Geoffrey ^h  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^d NewYork Presbyterian Hospital   (Tanzania)

^e Ministry of Health ^*  (Kenya)

^f Ministry of Health and Social Services   (Namibia)

^g MINISTRY OF HEALTH   (Kenya)

^h Elderly and Children   (Tanzania)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; COTRIMOXAZOLE;

ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; CONDOM; CONTROLLED STUDY; DEMOGRAPHY; DISEASE DURATION; DOCTOR PATIENT RELATION; EDUCATIONAL STATUS; FEASIBILITY STUDY; FEMALE; HEALTH STATUS; HIGH RISK BEHAVIOR; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION RISK; KENYA; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MARRIAGE; MULTICENTER STUDY; NAMIBIA; PATIENT CARE; PATIENT COMPLIANCE; PATIENT COUNSELING; PATIENT EDUCATION; RANDOMIZED CONTROLLED TRIAL; SEXUALLY TRANSMITTED DISEASE; TANZANIA; UNSAFE SEX; VIRUS TRANSMISSION;

ADOLESCENT; ADULT; DELIVERY OF HEALTH CARE; DEMOGRAPHY; FEMALE; HEALTH BEHAVIOR; HEALTH STATUS; HIV INFECTIONS; HUMANS; KENYA; MALE; MEDICATION ADHERENCE; MIDDLE AGED; NAMIBIA; RISK-TAKING; TANZANIA; YOUNG ADULT;

EID: 84874533561     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057215     Document Type: Article

References (49)

1. UN Joint Programme on HIV/AIDS (UNAIDS) (2011) UNAIDS Data Tables 2011.
2. UN Joint Programme on HIV/AIDS (UNAIDS) (2010) UNAIDS Report on the Global AIDS Epidemic.
3. Crum NF, Rittenburgh RH, Wegner S, Tasker S, Spooner K, et al. (2006) Comparisons of causes of death and mortality rates among HIV-infected persons: analysis of the pre-, early, and late HAART (highly active antiretroviral therapy) eras. Journal of Acquired Immune Deficiency Syndromes 41: 194-200.
4. World Health Organization (WHO) (2008) Essential prevention and care interventions for adults and adolescents living with HIV in resource-limited settings. Geneva: WHO.
5. Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, et al. (2011) Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med 365: 493-505.
6. World Health Organization (WHO) (2004) Gender dimensions of HIV status disclosure to sexual partners: rates, barriers, and outcomes.
7. Obermeyer CMBP, Pegurri E, (2011) Facilitating HIV disclosure across diverse settings: a review. Am J Public Health 101: 1011-1023.
8. King R, Katuntu D, Lifshay J, Packel L, Batamwita R, et al. (2008) Processes and outcomes of HIV serostatus disclosure to sexual partners among people living with HIV in Uganda. AIDS and Behavior 12: 232-243.
9. Dunkle KL, Stephenson R, Karita E, Chomba E, Kayitenkore K, et al. (2008) New heterosexually transmitted HIV infections in married or cohabiting couples in urban Zambia and Rwanda: an analysis of survey and clinical data. Lancet 371: 2183-2191.
10. Kenya National Bureau of Statistics (KNBS) and ICF Macro (2010) Kenya Demographic and Health Survey 2008-09. In: Macro I, editor. Calverton, Maryland: KNBS and ICF Macro.
11. Chemaitelly HCI, Shelton J, Hallett TB, Abu-Raddad LJ, (2012) Distinct HIV discordancy patterns by epidemic size in stable sexual partnerships in sub-Saharan Africa. Sex Transm Infect 88: 51-57.
12. Bunnell R, Opio A, Musinguzi J, Kirungi W, Ekwaru P, et al. (2008) HIV transmission risk behavior among HIV-infected adults in Uganda: results of a nationally representative survey. AIDS 22: 617-624.
13. Shuper PA, Joharchi N, Irving H, Rehm J, (2009) Alcohol as a correlate of unprotected sexual behavior among people living with HIV/AIDS: review and meta-analysis. AIDS and Behavior 13: 1021-1936.
14. Fisher JC, Bang H, Kapiga S, (2007) The association between HIV infection and alcohol use: a systematic review and meta-analysis of African studies. Sexually Transmitted Diseases 34: 856-863.
15. Palepu A, Horton N, Tibbetts N, Meli S, Samet J, (2004) Uptake and adherence to highly active antiretroviral therapy among HIV-infected people with alcohol and other substance use problems: the impact of substance abuse treatment. Addiction 99: 361-368.
16. World Health Organization (WHO) (2003) Guidelines for the Management of Sexually Transmitted Infections.
17. Homsy J, Bunnell R, Moore D, King R, Malamba S, et al. (2009) Reproductive intentions and outcomes among women on antiretroviral therapy in rural Uganda: a prospective cohort study. PLoS ONE 4: e4149.
18. Richardson JL, Milam J, McCutchan A, Stoyanoff S, Bolan R, et al. (2004) Effect of brief safer-sex counseling by medical providers to HIV-1 seropositive patients: a multi-clinic assessment. AIDS 18: 1179-1186.
19. Reynolds NR, Sun J, Nagaraja HN, Gifford AL, Wu AW, et al. (2007) Optimizing measurement of self-reported adherence with the ACTG Adherence Questionnaire: a cross-protocol analysis. Journal of Acquired Immune Deficency Syndromes 46: 402-409.
20. Chesney MA, Ickovics JR, Chambers DB, Gifford AL, Neidig J, et al. (2000) Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: the AACTG adherence instruments. AIDS Care: Psychological and Socio-medical Aspects of HIV/AIDS 12: 255-266.
21. Babor TF, Higgins-Biddle JC, Saunders JB, Monteiro MG (2001) The Alcohol Use Disorders Identification Test: Guidelines for use in primary care. Geneva, Switzerland: World Health Organization.
22. Namibia Ministry of Health and Social Services (MoHSS) and Macro International Inc. (2008) Namibia Demographic and Health Survey 2006-07. In: Inc MI, editor. Calverton, Maryland and Windhoek, Namibia.
23. Tanzania National Bureau of Statistics (NBS) and ICF Macro (2011) Tanzania Demographic and Health Survey 2010. Calverton, Maryland and Dar es Salaam, Tanzania.
24. Hardon AP, Akurut D, Comoro C, Ekezie C, Irunde HF, et al. (2007) Hunger, waiting time and transport costs: time to confront challenges to ART adherence in Africa. AIDS care 19: 658-665.
25. Mukherjee JS, Ivers L, Leandre F, Farmer P, Behforouz H, (2006) Antiretroviral therapy in resource-poor settings. Decreasing barriers to access and promoting adherence. J Acquir Immune Defic Syndr 43 Suppl 1: S123-126.
26. Tuller DM, Bangsberg DR, Senkungu J, Ware NC, Emenyonu N, et al. (2010) Transportation costs impede sustained adherence and access to HAART in a clinic population in southwestern Uganda: a qualitative study. AIDS Behav 14: 778-784.
27. Macro I (2006) Measure DHS: Model Questionnaire. Calverton, Maryland.
28. Abaynew Y, Deribew A, Deribe K, (2011) Factors associated with late presentation to HIV/AIDS care in South Wollo Zone Ethiopia: a case-control study. AIDS Research and Therapy 8: 8.
29. Lawn SD, Harries AD, Anglaret X, Myer L, Wood R, (2008) Early mortality among adults accessing antiretroviral treatment programmes in sub-Saharan Africa. AIDS 22: 1897-1908.
30. Kigozi IM, Dobkin LM, Martin JN, Geng EH, Muyindike W, et al. (2009) Late disease stage at presentation to an HIV clinic in the era of free antiretroviral therapy in sub-Saharan Africa. Journal of Acquired Immune Deficiency Syndromes 52: 280.
31. Battegay M, Fluckiger U, Hirschel B, Furrer H, (2007) Late presentation of HIV-infected individuals. Antiviral Therapy 12: 841-851.
32. Lancet, (2011) HIV treatment as prevention- it works. Lancet 377: 1719.
33. National Institutes of Allergy and Infectious Diseases (NIAID) (2011) Treating HIV-infected people with antiretrovirals protects partners from infection [press release].
34. Quinn TC, Wawer MJ, Sewankambo N, Serwadda D, Li C, et al. (2000) Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group. New England Journal of Medicine 342: 921-929.
35. Attia S, Egger M, Muller M, Zwahlen M, Low N, (2009) Sexual transmission of HIV according to viral load and antiretroviral therapy: systematic review and meta-analysis. AIDS 23: 1397-1404.
36. Donnell D, Baeten JM, Kiaire J, Thomas KK, Stevens W, et al. (2010) Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis. Lancet 375: 2092-2098.
37. Braitstein P, Boulle A, Nash D, Brinkhof MW, Dabis F, et al. (2008) Gender and the use of antiretroviral treatment in resource-constrained settings: findings from a multicenter collaboration. J Womens Health (Larchmt) 17: 47-55.
38. Cornell M, Myer L, Kaplan R, Bekker LG, Wood R, (2009) The impact of gender and income on survival and retention in a South African antiretroviral therapy programme. Tropical Medicine and International Health 14: 722-731.
39. Mulissa Z, Degu J, Bernt L, (2010) Patients present earlier and survival has improved, but pre-ART attrition is high in a six-year HIV cohort data from Ethiopia. PLoS ONE 5: e13268.
40. Gust DA, Mosimaneotsile B, Mathebula U, Chingapane B, Gaul Z, et al. (2011) Risk factors for non-adherence and loss to follow-up in a three-year clinical trial in Botswana. PLoS ONE 6: e18435.
41. Ekouevi DK, Balestre E, Ba-Gomis FO, Eholie SP, Maiga M, et al. (2010) Low retention of HIV-infected patients on antiretroviral therapy in 11 clinical centres in West Africa. Trop Med Int Health 15 Suppl 1: 34-42.
42. Charurat M, Oyegunle M, Benjamin R, Habib A, Eze E, et al. (2010) Patient retention and adherence to antiretrovirals in a large antiretroviral therapy program in Nigeria: a longitudinal analysis for risk factors. PLoS ONE 5: e10584.
43. Bhat VG, Ramburuth M, Singh M, Titi O, Antony AP, et al. (2010) Factors associated with poor adherence to anti-retroviral therapy in patients attending a rural health centre in South Africa. Eur J Clin Microbiol Infect Dis 29: 947-953.
44. Do NT, Phiri K, Bussmann H, Gaolathe T, Marlink RG, et al. (2010) Psychosocial factors affecting medication adherence among HIV-1 infected adults receiving combination antiretroviral therapy (cART) in Botswana. AIDS Res Hum Retroviruses 26: 685-691.
45. Mellins CA, Havens JF, McDonnell C, Lichtenstein C, Uldall K, et al. (2009) Adherence to antiretroviral medications and medical care in HIV-infected adults diagnosed with mental and substance abuse disorders. AIDS care 21: 168-177.
46. Cohn SE, Jiang H, McCutchan JA, Koletar SL, Murphy RL, et al. (2011) Association of ongoing drug and alcohol use with non-adherence to antiretroviral therapy and higher risk of AIDS and death: results from ACTG 362. AIDS care 23: 775-785.
47. Hahn JA, Samet JH, (2010) Alcohol and HIV disease progression: weighing the evidence. Curr HIV/AIDS Rep 7: 226-233.
48. Samet JH, Cheng DM, Libman H, Nunes DP, Alperen JK, et al. (2007) Alcohol consumption and HIV disease progression. J Acquir Immune Defic Syndr 46: 194-199.
49. Coldiron ME, Stephenson R, Chomba E, Vwalika C, Karita E, et al. (2008) The relationship between alcohol consumption and unprotected sex among known HIV-discordant couples in Rwanda and Zambia. AIDS Behav 12: 594-603.