-
1
-
-
70350103708
-
Class effects of tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia
-
Giles FJ, O'Dwyer M, Swords R. Class effects of tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia. Leukemia. 2009;23(10):1698-707.
-
(2009)
Leukemia
, vol.23
, Issue.10
, pp. 1698-1707
-
-
Giles, F.J.1
O'Dwyer, M.2
Swords, R.3
-
2
-
-
20944442975
-
Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate
-
Cortes J, Talpaz M, O'Brien S, Jones D, Luthra R, Shan J, et al. Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate. Clin Cancer Res. 2005; 11(9):3425-32.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.9
, pp. 3425-3432
-
-
Cortes, J.1
Talpaz, M.2
O'Brien, S.3
Jones, D.4
Luthra, R.5
Shan, J.6
-
3
-
-
34548825795
-
Bcr-Abl kinase domain mutations, drug resistance, and the road to a cure or chronic myeloid leukemia
-
O'Hare T, Eide CA, Deininger MW. Bcr-Abl kinase domain mutations, drug resistance, and the road to a cure or chronic myeloid leukemia. Blood. 2007;110(7):2242-9.
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2242-2249
-
-
O'Hare, T.1
Eide, C.A.2
Deininger, M.W.3
-
4
-
-
50949119729
-
Failure to achieve a major cytogenetic response by 12 months defines inadequate response in patients receiving nilotinib or dasatinib as second or subsequent line therapy for chronic myeloid leukemia
-
Tam CS, Kantarjian H, Garcia-Manero G, Borthakur G, O'Brien S, Ravandi F, et al. Failure to achieve a major cytogenetic response by 12 months defines inadequate response in patients receiving nilotinib or dasatinib as second or subsequent line therapy for chronic myeloid leukemia. Blood. 2008;112(3):516-8.
-
(2008)
Blood
, vol.112
, Issue.3
, pp. 516-518
-
-
Tam, C.S.1
Kantarjian, H.2
Garcia-Manero, G.3
Borthakur, G.4
O'Brien, S.5
Ravandi, F.6
-
5
-
-
73349122639
-
Chronic myeloid leukemia: An update of concepts and management recommendations of European Leukemia Net
-
Baccarani M, Cortes J, Pane F, Niederwieser D, Saglio G, Apperley J, et al. Chronic myeloid leukemia: an update of concepts and management recommendations of European Leukemia Net. J Clin Oncol. 2009;27(35):6041-51.
-
(2009)
J Clin Oncol
, vol.27
, Issue.35
, pp. 6041-6051
-
-
Baccarani, M.1
Cortes, J.2
Pane, F.3
Niederwieser, D.4
Saglio, G.5
Apperley, J.6
-
6
-
-
74149095067
-
Choosing the best treatment strategy for chronic myeloid leukemia patients resistant to imatinib weighing the efficacy and safety of individual drugs with BCR-ABL mutations and patient history
-
Jabbour E, Hochhaus A, Cortes J, La Rosée P, Kantarjian HM. Choosing the best treatment strategy for chronic myeloid leukemia patients resistant to imatinib weighing the efficacy and safety of individual drugs with BCR-ABL mutations and patient history. Leukemia. 2010;24(1):6-12.
-
(2010)
Leukemia
, vol.24
, Issue.1
, pp. 6-12
-
-
Jabbour, E.1
Hochhaus, A.2
Cortes, J.3
la Rosée, P.4
Kantarjian, H.M.5
-
7
-
-
36549088120
-
Part II: Management of resistance to imatinib in chronic myeloid leukaemia
-
Apperley JF. Part II: management of resistance to imatinib in chronic myeloid leukaemia. Lancet Oncol. 2007;8(12):1116-28.
-
(2007)
Lancet Oncol
, vol.8
, Issue.12
, pp. 1116-1128
-
-
Apperley, J.F.1
-
8
-
-
73349100015
-
The use of nilotinib or dasatinib after failure to prior tyrosine kinase inhibitors: Long-term follow-up
-
Garg RJ, Kantarjian H, O'Brien S, Quintás-Cardama A, Faderl F, Estrov Z, et al. The use of nilotinib or dasatinib after failure to prior tyrosine kinase inhibitors: long-term follow-up. Blood. 2009;114(20):4361-8.
-
(2009)
Blood
, vol.114
, Issue.20
, pp. 4361-4368
-
-
Garg, R.J.1
Kantarjian, H.2
O'Brien, S.3
Quintás-Cardama, A.4
Faderl, F.5
Estrov, Z.6
-
9
-
-
0348140591
-
Mechanisms and implications of imatinib resistance mutations in bcr-abl
-
Nardi V, Azam M, Daley GQ. Mechanisms and implications of imatinib resistance mutations in bcr-abl. Curr Opin Hematol. 2004;11(1):35-43.
-
(2004)
Curr Opin Hematol
, vol.11
, Issue.1
, pp. 35-43
-
-
Nardi, V.1
Azam, M.2
Daley, G.Q.3
-
10
-
-
0038375012
-
Several Bcr-Abl kinase domain mutants associated with imatinib mesylate resistance remain sensitive to imatinib
-
Corbin AS, Rosee PL, Stoffregen EP, Druker BJ, Deininger MW. Several Bcr-Abl kinase domain mutants associated with imatinib mesylate resistance remain sensitive to imatinib. Blood. 2003;101(11):4611-4.
-
(2003)
Blood
, vol.101
, Issue.11
, pp. 4611-4614
-
-
Corbin, A.S.1
Rosee, P.L.2
Stoffregen, E.P.3
Druker, B.J.4
Deininger, M.W.5
-
11
-
-
33846200681
-
Dasatinib (BMS-354825) is active in Philadelphia Chromosome-positive chronic myelogenous leukemia after imatinib and nilotinib (AMN107) therapy failure
-
Quintas-Cardama A, Kantarjian H, Jones D, Nicaise C, O'Brien S, Giles F, et al. Dasatinib (BMS-354825) is active in Philadelphia Chromosome-positive chronic myelogenous leukemia after imatinib and nilotinib (AMN107) therapy failure. Blood. 2007;109(2):497-9.
-
(2007)
Blood
, vol.109
, Issue.2
, pp. 497-499
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
Jones, D.3
Nicaise, C.4
O'Brien, S.5
Giles, F.6
-
12
-
-
33745102555
-
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
Talpaz M, Shah NP, Kantarjian H, Donato N, Nicoll J, Paquette R, et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. New Engl J Med. 2006;354(24):2531-41.
-
(2006)
New Engl J Med
, vol.354
, Issue.24
, pp. 2531-2541
-
-
Talpaz, M.1
Shah, N.P.2
Kantarjian, H.3
Donato, N.4
Nicoll, J.5
Paquette, R.6
-
13
-
-
33745086350
-
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
-
Kantarjian H, Giles F, Wunderle L, Bhalla K, O'Brien S, Wassmann B, et al. Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. New Engl J Med. 2006;354(24):2542-51.
-
(2006)
New Engl J Med
, vol.354
, Issue.24
, pp. 2542-2551
-
-
Kantarjian, H.1
Giles, F.2
Wunderle, L.3
Bhalla, K.4
O'Brien, S.5
Wassmann, B.6
-
14
-
-
36348968931
-
Nilotinib (formerly AMN107), a highly selective Bcr-Abl tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance
-
Kantarjian HM, Giles F, Gattermann N, Bhalla K, Alimena G, Palandri F, et al. Nilotinib (formerly AMN107), a highly selective Bcr-Abl tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance. Blood. 2007;110(10):3540-6.
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3540-3546
-
-
Kantarjian, H.M.1
Giles, F.2
Gattermann, N.3
Bhalla, K.4
Alimena, G.5
Palandri, F.6
-
15
-
-
49249121723
-
Intermittent target inhibition with dasatinib 100 mg once daily preserves efficacy and improves tolerability in imatinib-resistant and -intolerant chronic-phase chronic myeloid leukemia
-
Shah NP, Kantarjian HM, Kim DW, Rea D, Dorlhiac-Llacer PE, Milone JH, et al. Intermittent target inhibition with dasatinib 100 mg once daily preserves efficacy and improves tolerability in imatinib-resistant and -intolerant chronic-phase chronic myeloid leukemia. J Clin Oncol. 2008; 26(19):3204-12.
-
(2008)
J Clin Oncol
, vol.26
, Issue.19
, pp. 3204-3212
-
-
Shah, N.P.1
Kantarjian, H.M.2
Kim, D.W.3
Rea, D.4
Dorlhiac-Llacer, P.E.5
Milone, J.H.6
-
16
-
-
0037186915
-
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
-
Kantarjian H, Sawyers C, Hochhaus A, Guilhot F, Schiffer C, Gambacorti-Passerini C, et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. New Engl J Med. 2002;346(9):645-52.
-
(2002)
New Engl J Med
, vol.346
, Issue.9
, pp. 645-652
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
Guilhot, F.4
Schiffer, C.5
Gambacorti-Passerini, C.6
-
17
-
-
0042528659
-
Prognostic factors for patients with chronic myeloid leukaemia in chronic phase treated with imatinib mesylate after failure of interferon alfa
-
Marin D, Marktel S, Bua M, Szydlo RM, Franceschino A, Nathan I, et al. Prognostic factors for patients with chronic myeloid leukaemia in chronic phase treated with imatinib mesylate after failure of interferon alfa. Leukemia. 2003;17(8):1448-53.
-
(2003)
Leukemia
, vol.17
, Issue.8
, pp. 1448-1453
-
-
Marin, D.1
Marktel, S.2
Bua, M.3
Szydlo, R.M.4
Franceschino, A.5
Nathan, I.6
-
18
-
-
67349233062
-
Six-year follow up of patients receiving imatinib for the first line treatment of chronic myeloid leukemia
-
Hochhaus A, O'Brien SG, Guilhot F, Druker BJ, Branford S, Foroni L, et al. Six-year follow up of patients receiving imatinib for the first line treatment of chronic myeloid leukemia. Leukemia. 2009;23(6):1054-61.
-
(2009)
Leukemia
, vol.23
, Issue.6
, pp. 1054-1061
-
-
Hochhaus, A.1
O'Brien, S.G.2
Guilhot, F.3
Druker, B.J.4
Branford, S.5
Foroni, L.6
-
19
-
-
77949767505
-
International randomized study of interferon vs STI571(IRIS) 8-year follow-up: Sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib
-
Deininger MW, O'Brien SG, Guilhot F, Goldman JM, Hochhaus A, Hughes TP, et al. International randomized study of interferon vs STI571(IRIS) 8-year follow-up: sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib. Blood. 2009;114(22):1126.
-
(2009)
Blood
, vol.114
, Issue.22
, pp. 1126
-
-
Deininger, M.W.1
O'Brien, S.G.2
Guilhot, F.3
Goldman, J.M.4
Hochhaus, A.5
Hughes, T.P.6
-
20
-
-
55549116112
-
Nilotinib therapy after dasatinib failure in patients with imatinib-resistant or -intolerant chronic myeloid leukemia (CML) in chronic phase (CP), accelerated phase (AP), or blast crisis (BC)
-
Giles FJ, le Coutre P, Bhalla K, Ossenkoppele G, Alimena G, Haque A, et al. Nilotinib therapy after dasatinib failure in patients with imatinib-resistant or -intolerant chronic myeloid leukemia (CML) in chronic phase (CP), accelerated phase (AP), or blast crisis (BC). Blood. 2007;110(11): 1029.
-
(2007)
Blood
, vol.110
, Issue.11
, pp. 1029
-
-
Giles, F.J.1
le Coutre, P.2
Bhalla, K.3
Ossenkoppele, G.4
Alimena, G.5
Haque, A.6
-
21
-
-
76549114789
-
Early prediction of success or failure using second generation tyrosine kinase inhibitors for chronic myeloid leukemia
-
Milojkovic D, Nicholson E, Apperley JF, Holyoake TL, Shepherd P, Drummond MW, et al. Early prediction of success or failure using second generation tyrosine kinase inhibitors for chronic myeloid leukemia. Haematologica. 2010;95(2):224-31.
-
(2010)
Haematologica
, vol.95
, Issue.2
, pp. 224-231
-
-
Milojkovic, D.1
Nicholson, E.2
Apperley, J.F.3
Holyoake, T.L.4
Shepherd, P.5
Drummond, M.W.6
-
22
-
-
70349254450
-
Philadelphia-positive patients who already harbor imatinib-resistant Bcr-Abl kinase domain mutations have a higher likelihood off developing additional mutations associated with resistance to secondor third-line tyrosine kinase inhibitors
-
Soverini S, Gnani A, Colarossi S, Castagnetti F, Abruzzese E, Paolini S, et al. Philadelphia-positive patients who already harbor imatinib-resistant Bcr-Abl kinase domain mutations have a higher likelihood off developing additional mutations associated with resistance to secondor third-line tyrosine kinase inhibitors. Blood. 2009; 114(10):2168-71.
-
(2009)
Blood
, vol.114
, Issue.10
, pp. 2168-2171
-
-
Soverini, S.1
Gnani, A.2
Colarossi, S.3
Castagnetti, F.4
Abruzzese, E.5
Paolini, S.6
-
23
-
-
37049003546
-
Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors
-
Cortes J, Jabbour E, Kantarjian H, Yin CC, Shan J, O'Brien S, et al. Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors. Blood. 2007;110(12):4005-11.
-
(2007)
Blood
, vol.110
, Issue.12
, pp. 4005-4011
-
-
Cortes, J.1
Jabbour, E.2
Kantarjian, H.3
Yin, C.C.4
Shan, J.5
O'Brien, S.6
-
24
-
-
84860841611
-
Initial Findings From the PACE Trial: A Pivotal Phase 2 Study of Ponatinib in Patients with CML and Ph+ ALL Resistant or Intolerant to Dasatinib or Nilotinib, or with the T315I Mutation
-
Cortes J, Kim D, Pinilla-Ibarz J, Le Coutre P, Chuah C, Nicolini F, et al. Initial Findings From the PACE Trial: A Pivotal Phase 2 Study of Ponatinib in Patients with CML and Ph+ ALL Resistant or Intolerant to Dasatinib or Nilotinib, or with the T315I Mutation. Blood. 2011;118(21):109.
-
(2011)
Blood
, vol.118
, Issue.21
, pp. 109
-
-
Cortes, J.1
Kim, D.2
Pinilla-Ibarz, J.3
Le Coutre, P.4
Chuah, C.5
Nicolini, F.6
|