Q141K polymorphism of ABCG2 protein is associated with poor prognosis in adult acute myeloid leukemia treated with idarubicin-based chemotherapy

Haematologica

Volumn 98, Issue 3, 2013, Pages

  Tiribelli, Mario ^a,b   Fabbro, Dora ^a   Franzon, Alessandra ^a   Fanin, Renato ^a,b   Damante, Giuseppe ^a,b   Damiani, Daniela ^a,b  

^a UNIVERSITY HOSPITAL OF UDINE   (Italy)

^b UNIVERSITY OF UDINE   (Italy)

Author keywords

ABCG2; Acute myeloid leukemia; Anthracycline; Pharmacogenomics; Prognosis

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CD34 ANTIGEN; CYTARABINE; IDARUBICIN; ABC TRANSPORTER; ABCG2 PROTEIN, HUMAN; ANTINEOPLASTIC ANTIBIOTIC; TUMOR PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; CANCER PROGNOSIS; CANCER RECURRENCE; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DRUG MEGADOSE; FLOW CYTOMETRY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; LETTER; MAJOR CLINICAL STUDY; MUTATION; OVERALL SURVIVAL; PROTEIN EXPRESSION; REMISSION; TREATMENT OUTCOME; AMINO ACID SUBSTITUTION; GENETICS; LEUKEMIA, MYELOID, ACUTE; MIDDLE AGED; MORTALITY; PROGNOSIS; SINGLE NUCLEOTIDE POLYMORPHISM; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SUBSTITUTION; ANTIBIOTICS, ANTINEOPLASTIC; ATP-BINDING CASSETTE TRANSPORTERS; HUMANS; IDARUBICIN; LEUKEMIA, MYELOID, ACUTE; MIDDLE AGED; NEOPLASM PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; YOUNG ADULT;

EID: 84874509463     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.075895     Document Type: Letter

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