Aquaporin3 Is Required for FGF-2-Induced Migration of Human Breast Cancers

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Cao, Xu Chen ^a   Zhang, Wei Ran ^a   Cao, Wen Feng ^b   Liu, Bo Wen ^a   Zhang, Fei ^c   Zhao, Hong Meng ^a   Meng, Ran ^a   Zhang, Lin ^c   Niu, Rui Fang ^c   Hao, Xi Shan ^a   Zhang, Bin ^a  

^a Cancer Institute and Hospital   (China)

^b Tianjin Medical University ^*  (China)

^c TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 TERT BUTYL 3 [6 (3,5 DIMETHOXYPHENYL) 2 (4 DIETHYLAMINOBUTYLAMINO)PYRIDO[2,3 D]PYRIMIDIN 7 YL]UREA; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; AQUAPORIN 3; FIBROBLAST GROWTH FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA;

AQUAPORIN 3 GENE; ARTICLE; BREAST CANCER; CANCER CELL; CELL MIGRATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE SILENCING; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STABLE EXPRESSION; TUMOR GENE; UPREGULATION; WESTERN BLOTTING;

AQUAPORIN 3; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; COPPER SULFATE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; RECEPTORS, FIBROBLAST GROWTH FACTOR; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSDUCTION, GENETIC;

EID: 84874507945     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056735     Document Type: Article

References (28)

1. Papadopoulos MC, Saadoun S, Verkman AS, (2008) Aquaporins and cell migration. Pflugers Arch 456: 693-700.
2. Bikfalvi A, Klein S, Pintucci G, Rifkin DB, (1997) Biological roles of fibroblast growth factor-2. Endocr Rev 18: 26-45.
3. Ornitz DM, (2000) FGFs, heparan sulfate and FGFRs: complex interactions essential for development. Bioessays 22: 108-112.
4. Verkman AS, Hara-Chikuma M, Papadopoulos MC, (2008) Aquaporins-new players in cancer biology. J Mol Med (Berl) 86: 523-9.
5. Procino G, Mastrofrancesco L, Mira A, Tamma G, Carmosino M, et al. (2008) Aquaporin 2 and apical calcium-sensing receptor: new players in polyuric disorders associated with hypercalciuria. Semin Nephrol 28: 297-305.
6. Li H, Kamiie J, Morishita Y, Yoshida Y, Yaoita E, et al. (2005) Expression and localization of two isoforms of AQP10 in human small intestine. Biol Cell 97: 823-9.
7. Itoh T, Rai T, Kuwahara M, Ko SB, Uchida S, et al. (2005) Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells. Biochem Biophys Res Commun 330: 832-8.
8. Agre P, Kozono D, (2003) Aquaporin water channels: molecular mechanisms for human diseases. FEBS Lett 555: 72-8.
9. Verkman AS, (2005) More than just water channels: unexpected cellular roles of aquaporins. J Cell Sci 118 (Pt 15): 3225-32.
10. Zhang Z, Chen Z, Song Y, Zhang P, Hu J, et al. (2010) Expression of aquaporin 5 increases proliferation and metastasis potential of lung cancer. J Pathol 221: 210-20.
11. Hu J, Verkman AS, (2006) Increased migration and metastatic potential of tumor cells expressing aquaporin water channels. FASEB J 20: 1892-4.
12. Moon C, Soria JC, Jang SJ, Lee J, Obaidul Hoque M, et al. (2003) Involvement of aquaporins in colorectal carcinogenesis. Oncogene 22: 6699-703.
13. Ji C, Cao C, Lu S, Kivlin R, Amaral A, et al. (2008) Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells. Cancer Chemother Pharmacol 62: 857-865.
14. Ding T, Gu F, Fu L, Ma YJ, (2010) Aquaporin-4 in glioma invasion and an analysis of molecular mechanisms. J Clin Neurosci 17: 1359-61.
15. Tan G, Sun SQ, Yuan DL, (2008) Expression of the water channel protein aquaporin-9 in human astrocytic tumors: correlation with pathological grade. J Int Med Res 36: 777-82.
16. Mazal PR, Stichenwirth M, Koller A, Blach S, Haitel A, et al. (2005) Expression of aquaporins and PAX-2 compared to CD10 and cytokeratin 7 in renal neoplasms: a tissue microarray study. Mod Patho l18: 535-40.
17. Shi Z, Zhang T, Luo L, Zhao H, Cheng J, et al. (2011) Aquaporins in human breast cancer: Identification and involvement in carcinogenesis of breast cancer. J Surg Oncol 106: 267-72.
18. Jung HJ, Park JY, Jeon HS, Kwon TH, (2011) Aquaporin-5: a marker protein for proliferation and migration of human breast cancer cells. PLoS One 6: e28492.
19. Otterbach F, Callies R, Adamzik M, Kimmig R, Siffert W, et al. (2010) Aquaporin 1 (AQP1) expression is a novel characteristic feature of a particularly aggressive subgroup of basal-like breast carcinomas. Breast Cancer Res Treat 120: 67-76.
20. Kasimir-Bauer S, Heubner M, Otterbach F, Kimmig R, Siffert W, et al. (2009) Prognostic relevance of the AQP5-1364C>A polymorphism in primary breast cancer. Mol Med Report 2: 645-50.
21. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, et al. (2003) Cell migration: integrating signals from front to back. Science 302: 1704-1709.
22. Vicente-Manzanares M, Webb DJ, Horwitz AR, (2005) Cell migration at a glance. J. Cell Sci. 118: 4917-4919.
23. McIntosh I, Bellus GA, Jab EW, (2000) The pleiotropic effects of fibroblast growth factor receptors in mammalian development. Cell Struct. Funct. 25: 85-96.
24. Okada-Ban M, Thiery JP, Jouanneau J, (2000) Fibroblast growth factor-2. Int. J. Biochem. Cell Biol. 32: 263-267.
25. Cavallaro U, Wu Z, Di Palo A, Montesano R, Pepper MS, et al. (1998) FGF-2 stimulates migration of Kaposi's sarcoma-like vascular cells by HGF-dependent relocalization of the urokinase receptor. FASEB J 12: 1027-34.
26. Khurana A, Liu P, Mellone P, Lorenzon L, Vincenzi B, et al. (2011) HSulf-1 modulates FGF-2- and hypoxia-mediated migration and invasion of breast cancer cells. Cancer Res 71: 2152-61.
27. Liu JF, Crepin M, Liu JM, Barritault D, Ledoux D, (2002) FGF-2 and TPA induce matrix metallo-proteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway. Biochem Biophys Res Commun 293: 1174-82.
28. Suyama K, Shapiro I, Guttman M, Hazan RB, (2002) A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor. Cancer Cell 2: 301-14.