Characterization of a Chromosomal Type II Toxin-Antitoxin System mazEaFa in the Cyanobacterium Anabaena sp. PCC 7120

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Ning, Degang ^a   Jiang, Yan ^a   Liu, Zhaoying ^a   Xu, Qinggang ^a  

^a JIANGSU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL TOXIN; MAZEAFA; MAZFA PROTEIN; REACTIVE OXYGEN METABOLITE; TOXIN ANTIBODY; UNCLASSIFIED DRUG;

ANABAENA; ARTICLE; BACTERIAL CELL; BACTERIAL CHROMOSOME; BACTERIAL GROWTH; BACTERIAL STRAIN; COLONY FORMING UNIT; CONTROLLED STUDY; ELECTRON TRANSPORT; ESCHERICHIA COLI; GENE LOCUS; NONHUMAN; OPERON; OXIDATIVE STRESS; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TOXIN SYNTHESIS; TYPE II SECRETION SYSTEM;

ANABAENA; ANTITOXINS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CHROMOSOMES, BACTERIAL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84874507920     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056035     Document Type: Article

References (52)

1. Schopf JW (2002) The fossil record: tracing the roots of the cyanobacterial lineag. In: Whitton BA, and Potts M, editor. The Ecology of Cyanobacteria: Kluwer Academic Publishers, Dordrecht/London/Boston. pp. 12-35.
2. Tandeau de Marsac N, Houmard J, (1993) Adaptation of cyanobacteria to environmental stimuli: new steps towards molecular mechanisms. FEMS Microbiol Lett 104: 119-189.
3. Lewis K, (2007) Persister cells, dormancy and infectious disease. Nat Rev Microbiol 5: 48-56.
4. Schwarz R, Forchhammer K, (2005) Acclimation of unicellular cyanobacteria to macronutrient deficiency: emergence of a complex network of cellular responses. Microbiology-Sgm 151: 2503-2514.
5. Yamaguchi Y, Inouye M, (2011) Regulation of growth and death in Escherichia coli by toxin-antitoxin systems. Nat Rev Microbiol 9: 779-790.
6. Kolodkin-Gal I, Verdiger R, Shlosberg-Fedida A, Engelberg-Kulka H, (2009) A differential effect of E. coli toxin-antitoxin systems on cell death in liquid media and biofilm formation. PLoS One 4: e6785.
7. Van Melderen L, Saavedra De Bast M, (2009) Bacterial toxin-antitoxin systems: more than selfish entities? PLoS Genet 5: e1000437.
8. Erental A, Sharon I, Engelberg-Kulka H, (2012) Two programmed cell death systems in Escherichia coli: An apoptotic-like death is inhibited by the mazEF-mediated death pathway. Plos Biol 10.
9. Gerdes K, Christensen SK, Lobner-Olesen A, (2005) Prokaryotic toxin-antitoxin stress response loci. Nat Rev Microbiol 3: 371-382.
10. Fozo EM, Hemm MR, Storz G, (2008) Small toxic proteins and the antisense RNAs that repress them. Microbiol Mol Biol Rev 72: 579-589.
11. Gerdes K, Wagner EG, (2007) RNA antitoxins. Curr Opin Microbiol 10: 117-124.
12. Fineran PC, Blower TR, Foulds IJ, Humphreys DP, Lilley KS, et al. (2009) The phage abortive infection system, ToxIN, functions as a protein-RNA toxin-antitoxin pair. Proc Natl Acad Sci U S A 106: 894-899.
13. Yamaguchi Y, Park JH, Inouye M, (2011) Toxin-antitoxin systems in bacteria and archaea. Annu Rev Genet 45: 61-79.
14. Mutschler H, Gebhardt M, Shoeman RL, Meinhart A, (2011) A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis. PLoS Biol 9: e1001033.
15. Pandey DP, Gerdes K, (2005) Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res 33: 966-976.
16. Makarova K, Wolf Y, Koonin E, (2009) Comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes. Biol Direct 4doi:10.1186/1745-6150-1184-1119.
17. Leplae R, Geeraerts D, Hallez R, Guglielmini J, Dreze P, et al. (2011) Diversity of bacterial type II toxin-antitoxin systems: a comprehensive search and functional analysis of novel families. Nucleic Acids Res 39: 5513-5525.
18. Christensen-Dalsgaard M, Jorgensen MG, Gerdes K, (2010) Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses. Mol Microbiol 75: 333-348.
19. Hazan R, Sat B, Engelberg-Kulka H, (2004) Escherichia coli mazEF-mediated cell death is triggered by various stressful conditions. J Bacteriol 186: 3663-3669.
20. Prysak MH, Mozdzierz CJ, Cook AM, Zhu L, Zhang Y, et al. (2009) Bacterial toxin YafQ is an endoribonuclease that associates with the ribosome and blocks translation elongation through sequence-specific and frame-dependent mRNA cleavage. Mol Microbiol 71: 1071-1087.
21. Singletary LA, Gibson JL, Tanner EJ, McKenzie GJ, Lee PL, et al. (2009) An SOS-regulated type 2 toxin-antitoxin system. J Bacteriol 191: 7456-7465.
22. Keren I, Shah D, Spoering A, Kaldalu N, Lewis K, (2004) Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli. J Bacteriol 186: 8172-8180.
23. Korch SB, Henderson TA, Hill TM, (2003) Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis. Mol Microbiol 50: 1199-1213.
24. Korch SB, Hill TM, (2006) Ectopic overexpression of wild-type and mutant hipA genes in Escherichia coli: effects on macromolecular synthesis and persister formation. J Bacteriol 188: 3826-3836.
25. Aizenman E, Engelberg-Kulka H, Glaser G, (1996) An Escherichia coli chromosomal "addiction module" regulated by guanosine [corrected] 3′,5′-bispyrophosphate: a model for programmed bacterial cell death. Proc Natl Acad Sci U S A 93: 6059-6063.
26. Sat B, Hazan R, Fisher T, Khaner H, Glaser G, et al. (2001) Programmed cell death in Escherichia coli: some antibiotics can trigger mazEF lethality. J Bacteriol 183: 2041-2045.
27. Rippka R, (1988) Isolation and purification of cyanobacteria. Methods Enzymol 167: 3-27.
28. Schreiter PP, Gillor O, Post A, Belkin S. Schmid RD, Bachmann TT, (2001) Monitoring of phosphorus bioavailability in water by an immobilized luminescent cyanobacterial reporter strain. Biosens bioelectron 16: 811-818.
29. Elhai JWC, (1988) A versatile class of positive-selection vectors based on the nonviability of palindrome-containing plasmids that allows cloning into long polylinkers. Gene 68: 119-138.
30. Black TA, Cai Y, Wolk CP, (1993) Spatial expression and autoregulation of hetR, a gene involved in the control of heterocyst development in Anabaena. Mol Microbiol 9: 77-84.
31. Ning D, Ye S, Liu B, Chang J, (2011) The proteolytic activation of the relNEs (ssr1114/slr0664) toxin-antitoxin system by both proteases Lons and ClpP2s/Xs of Synechocystis sp. PCC 6803. Curr Microbiol 63: 496-502.
32. Ning D, Xu X, (2004) alr0117, a two-component histidine kinase gene, is involved in heterocyst development in Anabaena sp. PCC 7120. Microbiology 150: 447-453.
33. Boileau C, Eme L, Brochier-Armanet C, Janicki A, Zhang CC, et al. (2011) A eukaryotic-like sulfiredoxin involved in oxidative stress responses and in the reduction of the sulfinic form of 2-Cys peroxiredoxin in the cyanobacterium Anabaena PCC 7120. New Phytol 191: 1108-1118.
34. Munoz-Martin MA, Mateo P, Leganes F, Fernandez-Pinas F, (2011) Novel cyanobacterial bioreporters of phosphorus bioavailability based on alkaline phosphatase and phosphate transporter genes of Anabaena sp. PCC 7120. Anal Bioanal Chem 400: 3573-3584.
35. Asada K (1994) Production and action of active oxygen species in photosynthetic tissues. In: Foyer CH, Mullineauxr PM, editors. Causes of Photooxidative Stress and Amelioration of Defense Systems in Plants: Boca Raton, FL: CRC Press. pp. 77-104.
36. M AM, (1984) Cyanobacterial cell inclusions. Annu Rev Microbiol 69: 114-120.
37. Wolk CP (2000) Heterocyst formation in Anabaena. In: Brun YV, editors. Prokaryotic development: ASM Press. Washington, D.C. pp. 83-104.
38. Buikema WJ, Haselkorn R, (2001) Expression of the Anabaena hetR gene from a copper-regulated promoter leads to heterocyst differentiation under repressing conditions. Proc Natl Acad Sci U S A 98: 2729-2734.
39. Korch SB, Contreras H, Clark-Curtiss JE, (2009) Three Mycobacterium tuberculosis Rel toxin-antitoxin modules inhibit mycobacterial growth and are expressed in infected human macrophages. J Bacteriol 191: 1618-1630.
40. Robson J, McKenzie JL, Cursons R, Cook GM, Arcus VL, (2009) The vapBC operon from Mycobacterium smegmatis is an autoregulated toxin-antitoxin module that controls growth via inhibition of translation. J Mol Biol 390: 353-367.
41. Amitai S, Yassin Y, Engelberg-Kulka H, (2004) MazF-mediated cell death in Escherichia coli: a point of no return. J Bacteriol 186: 8295-8300.
42. Pedersen K, Christensen S, Gerdes K, (2002) Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins. Mol Microbiol 45: 501-510.
43. Agarwal S, Agarwal S, Bhatnagar R, (2007) Identification and characterization of a novel toxin-antitoxin module from Bacillus anthracis. FEBS Lett 581: 1727-1734.
44. Florek P, Muchova K, Pavelcikova P, Barak I, (2008) Expression of functional Bacillus SpoIISAB toxin-antitoxin modules in Escherichia coli. FEMS Microbiol Lett 278: 177-184.
45. Khoo SK, Loll B, Chan WT, Shoeman RL, Ngoo L, et al. (2007) Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae. J Biol Chem 282: 19606-19618.
46. Nieto C, Cherny I, Khoo SK, de Lacoba MG, Chan WT, et al. (2007) The yefM-yoeB toxin-antitoxin systems of Escherichia coli and Streptococcus pneumoniae: functional and structural correlation. J Bacteriol 189: 1266-1278.
47. Zhao LX, Zhang JJ, (2008) Biochemical characterization of a chromosomal toxin-antitoxin system in Mycobacterium tuberculosis. FEBS Lett 582: 710-714.
48. Syed MA, Koyanagi S, Sharma E, Jobin MC, Yakunin AF, et al. (2011) The chromosomal mazEF Locus of Streptococcus mutans encodes a functional type II toxin-antitoxin addiction system. J Bacteriol 193: 1122-1130.
49. Zhang Y, Zhang J, Hoeflich KP, Ikura M, Qing G, et al. (2003) MazF cleaves cellular mRNAs specifically at ACA to block protein synthesis in Escherichia coli. Mol Cell 12: 913-923.
50. Nariya H, Inouye M, (2008) MazF, an mRNA interferase, mediates programmed cell death during multicellular Myxococcus development. Cell 132: 55-66.
51. Maisonneuve E, Shakespeare LJ, Jorgensen MG, Gerdes K, (2011) Bacterial persistence by RNA endonucleases. Proc Natl Acad Sci U S A 108: 13206-13211.
52. Chang JN, Ning DG, (2009) Identification of a Pair of Toxin-antitoxin (TA) Gene in the Chromosome of Cyanobacteria Synechocystis sp. PCC6803. Wei Sheng Wu Xue Tong Bao 36: 31-36.