Coupling mutagenesis and parallel deep sequencing to probe essential residues in a genome or gene

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 9, 2013, Pages

  Robins, William P ^a   Faruque, Shah M ^b   Mekalanos, John J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH   (Bangladesh)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIOPHAGE T7; CHEMICAL MUTAGENESIS; CONTROLLED STUDY; GENE FUNCTION; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC LINKAGE; GENETIC SELECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VIBRIO CHOLERAE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS; BACTERIOPHAGE T7; BASE PAIRING; CODON, NONSENSE; CODON, TERMINATOR; CONSERVED SEQUENCE; DNA-DIRECTED DNA POLYMERASE; DNA-DIRECTED RNA POLYMERASES; GENES, VIRAL; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION, MISSENSE; PODOVIRIDAE; PROTEIN STRUCTURE, TERTIARY; REFERENCE STANDARDS; SEQUENCE ANALYSIS, DNA; VIBRIO CHOLERAE; VIRAL PROTEINS;

EID: 84874482336     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222538110     Document Type: Article

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