A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus

Vaccine

Volumn 31, Issue 11, 2013, Pages 1464-1470

  Roy, Chad J ^a   Adams, A Paige ^b   Wang, Eryu ^b   Leal, Grace ^b   Seymour, Robert L ^b   Sivasubramani, Satheesh K ^a   Mega, William ^c   Frolov, Ilya ^d   Didier, Peter J ^a   Weaver, Scott C ^b  

^a TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^d University of Alabama at Birmingham   (United States)

Author keywords

Aerosol; Alphavirus; Encephalitis; Nonhuman primate; Vaccine

Indexed keywords

IMMUNOGLOBULIN G; SIN NAEEEV VACCINE; SIN SAEEEV VACCINE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS VACCINE;

AEROSOL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHIMERA; CONTROLLED STUDY; EASTERN EQUINE ENCEPHALITIS; EASTERN EQUINE ENCEPHALOMYELITIS VIRUS; EPIDEMIC; FEMALE; HEART RATE; HISTOPATHOLOGY; HYPERTHERMIA; IMMUNOGENICITY; INHALATION TEST; MACACA; MALE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; SINDBIS VIRUS; SURVIVAL; TELEMETRY; TEMPERATURE; VACCINATION;

AEROSOLS; ANIMALS; DISEASE MODELS, ANIMAL; DRUG CARRIERS; ENCEPHALITIS VIRUS, EASTERN EQUINE; ENCEPHALOMYELITIS, EQUINE; FEMALE; FEVER; GENETIC VECTORS; MACACA; MALE; SINDBIS VIRUS; SURVIVAL ANALYSIS; TACHYCARDIA; VACCINES, SYNTHETIC; VIRAL VACCINES;

EID: 84874433599     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2013.01.014     Document Type: Article

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