Analysis of JC virus DNA in NPSLE patients treated with different immunomodulatory agents

Lupus

Volumn 22, Issue 3, 2013, Pages 307-311

  Iacobaeus, E ^a   Hopia, L ^a   Khademi, M ^a   Lunden M ^b   Hammarin, A L ^b   Svenungsson, E ^c   Andersson, M ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Swedish Institute for Communicable Disease Control   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

JC virus; Neuropsychiatric systemic lupus erythematosus; progressive multifocal leukoencephalopathy

Indexed keywords

ALBUMIN; AZATHIOPRINE; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; CYCLOSPORIN; HYDROXYCHLOROQUINE; IMMUNOGLOBULIN; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; RITUXIMAB; VIRUS DNA;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ARTICLE; AUTOIMMUNE DISEASE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CEREBROSPINAL FLUID ANALYSIS; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; JC VIRUS; LATENT VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; NEUROLOGIC DISEASE; NEUROPSYCHIATRIC SYSTEMIC LUPUS ERYTHEMATOSUS; PLASMAPHERESIS; POLYMERASE CHAIN REACTION; POLYOMA VIRUS; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; QUANTITATIVE ANALYSIS; RHEUMATIC DISEASE; RISK ASSESSMENT; SYSTEMIC LUPUS ERYTHEMATOSUS; VIRUS DETECTION; VIRUS LOAD; VIRUS REACTIVATION;

ADULT; AGED; DNA, VIRAL; FEMALE; HUMANS; IMMUNOLOGIC FACTORS; JC VIRUS; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; LUPUS VASCULITIS, CENTRAL NERVOUS SYSTEM; MALE; MIDDLE AGED; VIRAL LOAD; YOUNG ADULT;

EID: 84874423174     PISSN: 09612033     EISSN: 14770962     Source Type: Journal    
DOI: 10.1177/0961203312470977     Document Type: Article

References (20)

1. Brooks BR, Walker DL. Progressive multifocal leukoencephalopathy. Neurol Clin. 1984 ; 2: 299-313
2. White FA, Ishaq M, Stoner GL, Frisque RJ. JC virus DNA is present in many human brain samples from patients without progressive multifocal leukoencephalopathy. J Virol. 1992 ; 66: 5726-5734
3. Gheuens S, Pierone G, Peeters P, Koralnik IJ. Progressive multifocal leukoencephalopathy in individuals with minimal or occult immunosuppression. J Neurol Neurosurg Psychiatri 2010; 81: 247-254.
4. Berger JR. Progressive multifocal leukoencephalopathy and newer biological agents. Drug Saf. 2010 ; 33: 969-983
5. Molloy ES, Calabrese LH. Progressive multifocal leukoencephalopathy: A national estimate of frequency in systemic lupus erythematosus and other rheumatic diseases. Arthritis Rheum. 2009 ; 60: 3761-3765
6. Govindappa V, Hicks S, Wichter M, Jolly M. Progressive multifocal leukoencephalopathy in systemic lupus erythematosus. Arthritis Rheum. 2007 ; 57: 352-354
7. Nived O, Bengtsson AA, Jonsen A, Sturfelt G. Progressive multifocal leukoencephalopathy - the importance of early diagnosis illustrated in four cases. Lupus. 2008 ; 17: 1036-1041
8. The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes. Arthritis Rheum 1999; 42: 599-608.
9. Roberts JR, Finger DR. Progressive multifocal leukoencephalopathy mimicking central nervous system lupus. J Rheumatol. 2007 ; 34: 2119-2120
10. Iacobaeus E, Ryschkewitsch C, Gravell M, et al. Analysis of cerebrospinal fluid and cerebrospinal fluid cells from patients with multiple sclerosis for detection of JC virus DNA. Mult Scler. 2009 ; 15: 28-35
11. Molloy ES. PML and rheumatology: The contribution of disease and drugs. Cleve Clin J Med. 2011 ; 78 (Suppl 2). S28 - S32
12. Calabrese LH, Molloy ES, Huang D, Ransohoff RM. Progressive multifocal leukoencephalopathy in rheumatic diseases: Evolving clinical and pathologic patterns of disease. Arthritis Rheum. 2007 ; 56: 2116-2128
13. Molloy ES, Calabrese LH. Progressive multifocal leukoencephalopathy associated with immunosuppressive therapy in rheumatic diseases: Evolving role of biologic therapies. Arthritis Rheum. 2012 ; 64: 3043-3051
14. Amend KL, Turnbull B, Foskett N, Napalkov P, Kurth T, Seeger J. Incidence of progressive multifocal leukoencephalopathy in patients without HIV. Neurology. 2010 ; 75: 1326-1332
15. White MK, Khalili K. Pathogenesis of progressive multifocal leukoencephalopathy - revisited. J Infect Dis. 2011 ; 203: 578-586
16. Bayliss J, Karasoulos T, Bowden S, Glogowski I, McLean CA. Immunosuppression increases latent infection of brain by JC polyomavirus. Pathology. 2011 ; 43: 362-367
17. Sundsfjord A, Osei A, Rosenqvist H, et al. BK and JC viruses in patients with systemic lupus erythematosus: Prevalent and persistent BK viruria, sequence stability of the viral regulatory regions, and nondetectable viremia. J Infect Dis. 1999 ; 180: 1-9
18. Sadiq SA, Puccio LM, Brydon EW. JCV detection in multiple sclerosis patients treated with natalizumab. J Neurol. 2010 ; 257: 954-958
19. Rudick RA, O'Connor PW, Polman CH, et al. Assessment of JC virus DNA in blood and urine from natalizumab-treated patients. Ann Neurol. 2010 ; 68: 304-310
20. Brandão M, Damásio J, Marinho A, et al. Systemic lupus erythematosus, progressive multifocal leukoencephalopathy, and T-CD4+ lymphopenia. Clin Rev Allergy Immunol. 2012 ; 43: 302-307