Overexpression of SOCS3 in T lymphocytes leads to impaired interleukin-17 production and severe aortic aneurysm formation in mice-brief report

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 3, 2013, Pages 581-584

  Romain, Mélissa ^a   Taleb, Soraya ^a   Dalloz, Marion ^a   Ponnuswamy, Padmapriya ^a   Esposito, Bruno ^a   Pérez, Nicolas ^a   Wang, Yu ^a   Yoshimura, Akihiko ^b   Tedgui, Alain ^a   Mallat, Ziad ^a,c  

^a INSERM   (France)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

aneurysm; immunity; leukocytes

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 4; NEUTRALIZING ANTIBODY; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSFORMING GROWTH FACTOR BETA ANTIBODY;

ABDOMINAL AORTA ANEURYSM; ANEURYSM RUPTURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CARDIOVASCULAR MORTALITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; GENE DELETION; MACROPHAGE; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANGIOTENSIN II; ANIMALS; ANTIBODIES, NEUTRALIZING; AORTIC ANEURYSM, ABDOMINAL; AORTIC RUPTURE; BONE MARROW TRANSPLANTATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENOTYPE; INTERLEUKIN-17; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUTROPHILS; PHENOTYPE; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TH17 CELLS; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION; WHOLE-BODY IRRADIATION;

EID: 84874391124     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.300516     Document Type: Article

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