Ischaemic stroke and thrombolysis: Ask the onset time, not the age!

Internal and Emergency Medicine

Volumn 8, Issue 2, 2013, Pages 99-100

  Cenciarelli, Silvia ^a   Mazzoli, Tatiana ^a   Ricci, Stefano ^a  

^a Centro di Coordinamento IST 3 per l' Italia   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84874370369     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-012-0879-5     Document Type: Editorial

References (8)

1. SPREAD Italian National Guidelines for Stroke (2012) http://www. spread. it accessed on 30-9-2012.
2. Rudd AG, Hoffman A, Grant R, Campbell JT, Lowe D, On behalf of the intercollegiate working party for stroke (2009) Stroke thrombolysis in England, Wales and Northern Ireland: how much do we do and how much do we need? J Neurol Neurosurg Psychiatry 82: 13-19. doi: 10. 1136/jnnp.
3. The IST-3 collaborative group (2012) The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet 379(9834): 2352-2363.
4. Hacke W, Kaste M, Bluhmki E, Brozman M, Davalos A, Guidett D, Larrue V, Lees K, Medeghri Z, Machnig T, Schneider D, von Kummer R, Wahlgren N, and Toni D, for the ECASS Investigators (2008) Thrombolysis with Alteplase 3 to 4. 5 h after Acute Ischemic Stroke. NEJM 359: 1317-1329.
5. Saver J (2007) Novel end point analytic techniques and interpreting shifts across the entire range of outcome scales in acute stroke trials. Stroke 38: 3055-3062.
6. IST 3 Collaborative Group (2012) Statistical analysis plan for the third International Stroke Trial (IST-3); part of a 'thread' of reports of the trial. Int J Stroke 7: 186-187.
7. Wardlaw J, Murray V, Berge E, del Zoppo G, Sandercock P, Lindley R, Cohen G (2012) r-tPA for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet 379: 2364-2372.
8. Leys D, Cordonnier C (2012) rt-PA for ischaemic stroke: what will the next question be? Lancet 379: 2320-2321.