Association of cigarette smoking with aberrant methylation of the tumor suppressor gene RARβ2 in papillary thyroid cancer

Frontiers in Endocrinology

Volumn 2, Issue DEC, 2011, Pages

  Vassiliades, Katja Kiseljak ^a   Xing, Mingzhao ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gene; Methylation; RAR ; Thyroid cancer; Tobacco smoking; Tumor suppressor gene

Indexed keywords

EID: 84874348353     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2011.00099     Document Type: Article

References (30)

1. Bandurska-Stankiewicz, E., Aksamit-Bialoszewska, E., Rutkowska, J., Stankiewicz, A., and Shafie, D. (2011). The effect of nutritional habits and addictions on the incidence of thyroid carcinoma in the Olsztyn province of Poland. Endokrynol Pol. 62,145-150.
2. Coelho, S. M., Vaisman, M., and Carvalho, D. P. (2005). Tumour re-differentiation effect of retinoic acid: a novel therapeutic approach for advanced thyroid cancer. Curr. Pharm. Des. 11,2525-2531.
3. Elisei, R., Vivaldi, A., Agate, L., Ciampi, R., Molinaro, E., Piampiani, P., Romei, C., Faviana, P., Basolo, F., Miccoli, P., Capodanno, A., Col-lecchi, P., Pacini, F., and Pinchera, A. (2005). All-trans-retinoic acid treatment inhibits the growth of retinoic acid receptor beta messenger ribonucleic acid expressing thyroid cancer cell lines but does not reinduce the expression of thyroid-specific genes. J. Clin. Endocrinol. Metab. 90, 2403-2411.
4. Ericsson, U. B., and Lindgarde, E (1991). Effects of cigarette smoking on thyroid function and the prevalence of goitre, thyrotoxicosis and autoimmune thyroiditis. J. Intern. Med. 229, 67-71.
5. Esteller, M. (2008). Epigenetics in cancer. N. Engl. J. Med. 358,1148-1159.
6. Franceschi, S., Preston-Martin, S., Dal Maso, L., Negri, E., La Vecchia, C., Mack, W. J., Mctiernan, A., Kolonel, L., Mark, S. D., Mabuchi, K., Jin, E, Wingren, G., Galanti, R., Hal-lquist, A., Glattre, E., Lund, E., Levi, E, Linos, D., and Ron, E. (1999). A pooled analysis of case-control studies of thyroid cancer. IV. Benign thyroid diseases. Cancer Causes Control 10,583-595.
7. Galanti, M. R., Granath, F., Cnattingius, S., Ekbom-Schnell, A., and Ekbom, A. (2005). Cigarette smoking and the risk of goitre and thyroid nodules amongst parous women. J. Intern. Med. 258,257-264.
8. Haugen, B. R., Larson, L. L., Pugazhen-thi, U., Hays, W. R., Klopper, J. P., Kramer, C. A., and Sharma, V. (2004). Retinoic acid and retinoid X receptors are differentially expressed in thyroid cancer and thyroid carcinoma cell lines and predict response to treatment with retinoids. J. Clin. Endocrinol Metab. 89, 272-280.
9. Hoque, M. O., Rosenbaum, E., Wes-tra, W. H., Xing, M., Ladenson, P., Zeiger, M. A., Sidransky, D., and Umbricht, C. B. (2005). Quantitative assessment of promoter methylation profiles in thyroid neoplasms. J. Clin. Endocrinol Metab. 90, 4011-4018.
10. Howlader, N., Noone, A. M., Krap-cho, M., Neyman, N., Aminou, R., Waldron, W., Altekruse, S. F., Kosary, C. L., Ruhl, J., Tatalovich, Z., Cho, H., Mariotto, A., Eisner, M. P., Lewis, D. R., Chen, H. S., Feuer, E. J., Cronin, K. A., and Edwards, B. K. (eds). (2011). SEER Cancer Statistics Review 1975-2008. Bethesda, MD: National Cancer Institute.
11. Hu, S., Liu, D., Tufano, R. P., Carson, K. A., Rosenbaum, E., Cohen, Y., Holt, E. H., Kiseljak-Vassiliades, K., Rhoden, K. J., Tolaney, S., Con-douris, S., Tallini, G., Westra, W. H., Umbricht, C. B., Zeiger, M. A., Califano, J. A., Vasko, V., and Xing, M. (2006). Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer. Int. J. Cancer 119, 2322-2329.
12. Hundahl, S. A., Fleming, I. D., Frem-gen, A. M., and Menck, H. R. (1998). A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995. Cancer 83, 2638-2648. [See comments].
13. Kreiger, N., and Parkes, R. (2000). Cigarette smoking and the risk of thyroid cancer. Eur. J. Cancer 36, 1969-1973.
14. Lio, S., Napolitano, G., Marinuzzi, G., and Monaco, E (1989). Role of smoking in goiter morphology and thyrotropin response to TRH in untreated goitrous women. J. Endocrinol Invest. 12, 93-97.
15. Liu, Y., Gao, W., Siegfried, J. M., Weiss-feld, J. L., Luketich, J. D., and Keo-havong, P. (2007). Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers. BMC Cancer 7, 74. doi:10.1186/1471-2407-7-74.
16. Miasaki, E Y., Vivaldi, A., Ciampi, R., Agate, L., Collecchi, P., Capodanno, A., Pinchera, A., and Elisei, R. (2008). Retinoic acid receptor beta2 re-expression and growth inhibition in thyroid carcinoma cell lines after 5-aza-2'-deoxycytidine treatment. J. Endocrinol Invest. 31, 724-730.
17. Nikiforov, Y E. (2006). Radiation-induced thyroid cancer: what we have learned from chernobyl. Endocr. Pathol. 17, 307-317.
18. Paluszczak, J., Misiak, P., Wierzbicka, M., Wozniak, A., and Baer-Dubowska, W. (2011). Frequent hypermethyla-tion of DAPK, RARbeta, MGMT, RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa. Oral Oncol. 47, 104-107.
19. Pfahl, M., and Chytil, E (1996). Regulation of metabolism by retinoic acid and its nuclear receptors. Annu. Rev. Nutr. 16,257-283.
20. Preston-Martin, S., Jin, F., Duda, M. J., and Mack, W. J. (1993). A case-control study of thyroid cancer in women under age 55 in Shanghai (People's Republic of China). Cancer Causes Control 4,431-440.
21. Raffo, P., Emionite, L., Colucci, L., Belmondo, F., Moro, M. G., Bol-lag, W., and Toma, S. (2000). Retinoid receptors: pathways of proliferation inhibition and apop-tosis induction in breast cancer cell lines. Anticancer Res. 20, 1535-1543.
22. Ron, E., Kleinerman, R. A., Boice, J. D. Jr., Livolsi, V A., Flan-nery, J. T., and Fraumeni, J. F. Jr. (1987). A population-based case-control study of thyroid cancer. J. Natl Cancer Inst. 79, 1-12.
23. Sokic, S. I., Adanja, B. J., Vlajinac, H. D., Jankovic, R. R., Marinkovic, J. P., andZivaljevic, V.R. (1994). Risk factors for thyroid cancer. Neoplasma 41,371-374.
24. Tang, W., Nakamura, Y., Zuo, H., Yasuoka, H., Yang, Q., Wang, X., Nakamura, M., Mori, I., Miyauchi, A., and Kakudo, K. (2003). Differentiation, proliferation and retinoid receptor status of papillary carcinoma of the thyroid. Pathol Int. 53, 204-213.
25. Tomizawa, Y., Iijima, H., Nomoto, T., Iwasaki, Y., Otani, Y., Tsuchiya, S., Saito, R., Dobashi, K., Nakajima, T., and Mori, M. (2004). Clinico-pathological significance of aberrant methylation of RARbeta2 at 3p24, RASSF1A at 3p21.3, and FHIT at 3p14.2 in patients with non-small cell lung cancer. Lung Cancer 46, 305-312.
26. Treuting, P. M., Chen, L. I., Buetow, B. S., Zeng, W., Birkebak, T. A., Seewaldt, V L., Sommer, K. M., Emond, M., Maggio-Price, L., and Swisshelm, K. (2002). Retinoic acid receptor beta2 inhibition of metastasis in mouse mammary gland xenografts. Breast Cancer Res. Treat. 72, 79-88.
27. Vuillemenot, B. R., Pulling, L. C., Palmisano, W. A., Hutt, J. A., and Belinsky, S. A. (2004). Carcinogen exposure differentially modulates RAR-beta promoter hyperme-thylation, an early and frequent event in mouse lung carcinogenesis. Carcinogenesis 25, 623-629.
28. Widschwendter, M., Berger, J., Muller, H. M., Zeimet, A. G., and Marth, C. (2001). Epigenetic downregula-tion of the retinoic acid receptor-beta2 gene in breast cancer. J. Mammary Gland Biol. Neoplasia 6, 193-201.
29. Xing, M. (2007). Gene methylation in thyroid tumorigenesis. Endocrinology 148, 948-953.
30. Zochbauer-Muller, S., Lam, S., Toyooka, S., Virmani, A. K., Toyooka, K. O., Seidl, S., Minna, J. D., and Gazdar, A. E (2003). Aberrant methylation of multiple genes in the upper aerodi-gestive tract epithelium of heavy smokers. Int.J. Cancer 107,612-616.