Allergenic potential and enzymatic resistance of buckwheat

Nutrition Research and Practice

Volumn 7, Issue 1, 2013, Pages 3-8

  Lee, Sujin ^a   Han, Youngshin ^b   Do, Jeong Ryong ^c   Oh, Sangsuk ^a  

^a Ewha Womans University   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Korea Food Research Institute   (South Korea)

Author keywords

Allergenicity; Buckwheat; Chymotrypsin; Hydrolysis; Pepsin

Indexed keywords

EID: 84874309905     PISSN: 19761457     EISSN: 20056168     Source Type: Journal    
DOI: 10.4162/nrp.2013.7.1.3     Document Type: Article

References (25)

1. Wieslander G, Norbäck D. Buckwheat allergy. Allergy 2001;56: 703-4.
2. Park CH, Choi YS. Memil. Chuncheon: Kangwon National University Publishing Co.; 2004. p.35-43.
3. He J, Klag MJ, Whelton PK, Mo JP, Chen JY, Qian MC, Mo PS, He GQ. Oats and buckwheat intakes and cardiovascular disease risk factors inan ethnic minority of China. Am J Clin Nutr 1995;61:366-72.
4. Choe M, Kim JD, Park KS, Oh SY, Lee SY. Effect of buckwheat supplementation on blood glucose levels and blood pressure in rats. J Korean Soc Food Nutr 1991;20:300-5.
5. The Korean Academy of Asthma. Allergy and Clinical Immunology, 4 Chunmanyoi Allergy. Seoul: Yoihakmunhwasa Publishing Co.; 2005. p.85-92.
6. Smith HL. Buckwheat-poisoning with report of a case in man. Arch Intern Med (Chic) 1909;3:350-9.
7. Son DY, Yoon KR, Lee SI. Study of the most common allergic foods in Korea. Korean J Food Sci Technol 2002;34:885-8
8. Houben GF, Knippels LM, Penninks AH. Food allergy: predictive testing of food products. Environ Toxicol Pharmacol 1997;4:127-35
9. Tanaka K, Matsumoto K, Akasawa A, Nakajima T, Nagasu T, Iikura Y, Saito H. Pepsin-resistant 16-kD buckwheat protein is associated with immediate hypersensitivity reaction in patients with buckwheat allergy. Int Arch Allergy Immunol 2002;129: 49-56.
10. Kruger NJ. The bradford method for protein quantitation. In: Walker JM, editor. The Protein Protocols Handbook. 2nd ed. Totowa: Humana Press Inc.; 2002. p.15-21.
11. Kato H, van Chuyen N, Utsunomiya N, Okitani A. Changes of amino acids composition and relative digestibility of lysozyme in the reaction with alpha-dicarbonyl compounds in aqueous system. J Nutr Sci Vitaminol (Tokyo) 1986;32:55-65.
12. Keum EH, Lee SI, Oh S. Effect of enzymatic hydrolysis of 7S globulin, a soybean protein, on its allergenicity and identification of its allergenic hydrolyzed fragments using SDS-PAGE. Food Sci Biotechnol 2006;15:128-32.
13. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
14. Matsumoto R, Fujino K, Nagata Y, Hashiguchi S, Ito Y, Aihara Y, Takahashi Y, Maeda K, Sugimura K. Molecular characterization of a 10-kDa buckwheat molecule reactive to allergic patients' IgE. Allergy 2004;59:533-8.
15. Park JW, Kang DB, Kim CW, Ko SH, Yum HY, Kim KE, Hong CS, Lee KY. Identification and characterization of the major allergens of buckwheat. Allergy 2000;55:1035-41.
16. Nair A, Adachi T. Immunodetection and characterization of allergenic proteins in common buckwheat (Fagopyrum esculentum). Plant Biotechnol (Tsukuba) 1999;16:219-24.
17. Kondo Y, Urisu A, Wada E, Tsuruta M, Yasaki T, Yamada K, Masuda S, Morita Y. Allergen analysis of buckwheat by the immunoblotting method. Arerugi 1993;42:142-8.
18. Urisu A, Kondo Y, Morita Y. Identification of a major allergen of buckwheat seeds by immunoblotting methods. Allergy Clin Immunol News 1994;6:151-5.
19. Han Y, Kim J, Ahn K. Food allergy. Korean J Pediatr 2012;55: 153-8.
20. Yoshimasu MA, Zhang JW, Hayakawa S, Mine Y. Electro-phoretic and immunochemical characterization of allergenic proteins in buckwheat. Int Arch Allergy Immunol 2000;123:130-6.
21. Satoh R, Koyano S, Takagi K, Nakamura R, Teshima R. Identification of an IgE-binding epitope of a major buckwheat allergen, BWp16, by SPOTs assay and mimotope screening. Int Arch Allergy Immunol 2010;153:133-40.
22. IUIS Allergen Nomenclature [Internet]. Allergens of Buckwheat. a buckwheat 16-kDa major allergen. Int Arch Allergy Immunol [cited 2012 July 14]. Available from: http://www.allergen.org/.
23. Takagi K, Teshima R, Okunuki H, Sawada J. Comparative study of in vitro digestibility of food proteins and effect of preheating on the digestion. Biol Pharm Bull 2003;26:969-73.
24. Koyano S, Takagi K, Teshima R, Sawada J. Molecular cloning of cDNA, recombinant protein expression and characterization of 2006;140:73-81.
25. Satoh R, Koyano S, Takagi K, Nakamura R, Teshima R, Sawada J. Immunological characterization and mutational analysis of the recombinant protein BWp16, a major allergen in buckwheat. Biol Pharm Bull 2008;31:1079-85