-
1
-
-
78751676408
-
Cells of origin in cancer
-
Visvader JE, (2011) Cells of origin in cancer. Nature 469: 314-322.
-
(2011)
Nature
, vol.469
, pp. 314-322
-
-
Visvader, J.E.1
-
2
-
-
33750313208
-
Cancer stem cells - Perspectives on current status and future directions: AACR workshop on Cancer Stem Cells
-
Clarke MF, Dick JE, Dirks PB, Eaves CJ, Jamieson CHM, et al. (2006) Cancer stem cells- Perspectives on current status and future directions: AACR workshop on Cancer Stem Cells. Cancer Res 66: 9339-9344.
-
(2006)
Cancer Res
, vol.66
, pp. 9339-9344
-
-
Clarke, M.F.1
Dick, J.E.2
Dirks, P.B.3
Eaves, C.J.4
Jamieson, C.H.M.5
-
3
-
-
58149380742
-
Stem cell concepts renew cancer research
-
Dick JE, (2008) Stem cell concepts renew cancer research. Blood 112: 4793-4807.
-
(2008)
Blood
, vol.112
, pp. 4793-4807
-
-
Dick, J.E.1
-
4
-
-
79551555038
-
Cancer stem cell niche: The place to be
-
Borovski T, Melo FDSE, Vermeulen L, Medema JP, (2011) Cancer stem cell niche: The place to be. Cancer Res 71: 634-639.
-
(2011)
Cancer Res
, vol.71
, pp. 634-639
-
-
Borovski, T.1
Melo, F.D.S.E.2
Vermeulen, L.3
Medema, J.P.4
-
5
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF, (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100: 3983-3988.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
6
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE, (2007) A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445: 106-110.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
7
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM, et al. (2008) Efficient tumour formation by single human melanoma cells. Nature 456: 593-598.
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
-
8
-
-
44749086557
-
Growth of cancer cell lines under stem cell-like conditions has the potential to unveil therapeutic targets
-
Rappa G, Mercapide J, Anzanello F, Prasmickaite L, Xi Y, et al. (2008) Growth of cancer cell lines under stem cell-like conditions has the potential to unveil therapeutic targets. Exp Cell Res 314: 2110-2122.
-
(2008)
Exp Cell Res
, vol.314
, pp. 2110-2122
-
-
Rappa, G.1
Mercapide, J.2
Anzanello, F.3
Prasmickaite, L.4
Xi, Y.5
-
9
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ, (2005) Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65: 10946-10951.
-
(2005)
Cancer Res
, vol.65
, pp. 10946-10951
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
-
10
-
-
49149098126
-
Prowling wolves in sheep's clothing: the search for tumor stem cells
-
Alkatout I, Kabelitz D, Kalthoff H, Tiwari S, (2008) Prowling wolves in sheep's clothing: the search for tumor stem cells. Biol Chem 389: 799-811.
-
(2008)
Biol Chem
, vol.389
, pp. 799-811
-
-
Alkatout, I.1
Kabelitz, D.2
Kalthoff, H.3
Tiwari, S.4
-
11
-
-
80051967505
-
Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
-
Gupta PB, Fillmore CM, Jiang G, Shapira SD, Tao K, et al. (2011) Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell 146: 633-644.
-
(2011)
Cell
, vol.146
, pp. 633-644
-
-
Gupta, P.B.1
Fillmore, C.M.2
Jiang, G.3
Shapira, S.D.4
Tao, K.5
-
12
-
-
33751239783
-
Self-renewal of embryonic stem cells by a small molecule
-
Chen S, Do JT, Zhang Z, Yao S, Yan F, et al. (2006) Self-renewal of embryonic stem cells by a small molecule. Proc Natl Acad Sci USA 103: 17266-17271.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17266-17271
-
-
Chen, S.1
Do, J.T.2
Zhang, Z.3
Yao, S.4
Yan, F.5
-
13
-
-
33646358694
-
Tumor stem cells derived from gliobastomas cultured in bFGF and EGF closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
-
Lee J, Kotilarova S, Kotliarova Y, Li A, Sun Q, et al. (2006) Tumor stem cells derived from gliobastomas cultured in bFGF and EGF closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 9: 391-403.
-
(2006)
Cancer Cell
, vol.9
, pp. 391-403
-
-
Lee, J.1
Kotilarova, S.2
Kotliarova, Y.3
Li, A.4
Sun, Q.5
-
14
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, et al. (2007) Identification and expansion of human colon-cancer-initiating cells. Nature 445: 111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
-
15
-
-
39449090031
-
CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis
-
Hurt EM, Kawasaki BT, Klarmann GJ, Thomas SB, Farrar WL, (2008) CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis. Brit J Can 98: 756-765.
-
(2008)
Brit J Can
, vol.98
, pp. 756-765
-
-
Hurt, E.M.1
Kawasaki, B.T.2
Klarmann, G.J.3
Thomas, S.B.4
Farrar, W.L.5
-
16
-
-
34249980343
-
Identification and characterization of tumorigenic liver cancer stem/progenitor cells
-
Ma S, Chan KW, Hu L, Lee TK, Wo JY, et al. (2007) Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology 132: 2542-2556.
-
(2007)
Gastroenterology
, vol.132
, pp. 2542-2556
-
-
Ma, S.1
Chan, K.W.2
Hu, L.3
Lee, T.K.4
Wo, J.Y.5
-
17
-
-
33750809196
-
Characterization of CD133+ hepatocellular carcinoma cells as cancer stem/progenitor cells
-
Suetsugu A, Nagaki M, Aoki H, Motohashi T, Kunisada T, et al. (2006) Characterization of CD133+ hepatocellular carcinoma cells as cancer stem/progenitor cells. Biochem Biophys Res Comm 351: 820-824.
-
(2006)
Biochem Biophys Res Comm
, vol.351
, pp. 820-824
-
-
Suetsugu, A.1
Nagaki, M.2
Aoki, H.3
Motohashi, T.4
Kunisada, T.5
-
18
-
-
51649111430
-
Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
-
Vermeulen L, Todaro M, de Sousa Mello F, Sprick MR, Kemper K, et al. (2008) Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. Proc Natl Acad Sci USA 105: 13427-13432.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13427-13432
-
-
Vermeulen, L.1
Todaro, M.2
de Sousa Mello, F.3
Sprick, M.R.4
Kemper, K.5
-
19
-
-
0037948854
-
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
-
Dontu G, Abdallah WM, Foley JM, Jackson KW, Clarke ME, et al. (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17: 1253-1270.
-
(2003)
Genes Dev
, vol.17
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
Jackson, K.W.4
Clarke, M.E.5
-
20
-
-
34247398806
-
Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia
-
Moraes RC, Zhang X, Harrington N, Fung JY, Wu MF, et al. (2007) Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia. Development 134: 1231-1242.
-
(2007)
Development
, vol.134
, pp. 1231-1242
-
-
Moraes, R.C.1
Zhang, X.2
Harrington, N.3
Fung, J.Y.4
Wu, M.F.5
-
21
-
-
77950587482
-
Identification of vitronectin as an extrinsic inducer of cancer stem cell differentiation and tumor formation
-
Hurt EM, Chan K, Serrat MA, Thomas SB, Veenstra TD, et al. (2010) Identification of vitronectin as an extrinsic inducer of cancer stem cell differentiation and tumor formation. Stem Cells 28: 461-470.
-
(2010)
Stem Cells
, vol.28
, pp. 461-470
-
-
Hurt, E.M.1
Chan, K.2
Serrat, M.A.3
Thomas, S.B.4
Veenstra, T.D.5
-
22
-
-
79955679188
-
Eyes Wide Open: A critical review of sphere-formation as an assay for stem cells
-
Pastrana E, Silva-Vargas V, Doetsch F, (2011) Eyes Wide Open: A critical review of sphere-formation as an assay for stem cells. Cell Stem Cell 8: 486-498.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 486-498
-
-
Pastrana, E.1
Silva-Vargas, V.2
Doetsch, F.3
-
23
-
-
69649084228
-
The transcriptional foundation of pluripotency
-
Chambers I, Tomlinson SR, (2009) The transcriptional foundation of pluripotency. Development 136: 2311-2322.
-
(2009)
Development
, vol.136
, pp. 2311-2322
-
-
Chambers, I.1
Tomlinson, S.R.2
-
24
-
-
32244434299
-
Comprehensive analysis of pathway or functionally related gene expression in the National Cancer Institute's anticancer screen
-
Huang R, Wallqvist A, Covell DG, (2006) Comprehensive analysis of pathway or functionally related gene expression in the National Cancer Institute's anticancer screen. Genomics 87: 315-328.
-
(2006)
Genomics
, vol.87
, pp. 315-328
-
-
Huang, R.1
Wallqvist, A.2
Covell, D.G.3
-
25
-
-
33749557850
-
Targeting changes in cancer: Assessing pathway stability by comparing pathway gene expression coherence levels in tumor and normal tissues
-
Huang R, Wallqvist A, Covell DG, (2006) Targeting changes in cancer: Assessing pathway stability by comparing pathway gene expression coherence levels in tumor and normal tissues. Mol Cancer Ther 5: 2417-2427.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2417-2427
-
-
Huang, R.1
Wallqvist, A.2
Covell, D.G.3
-
26
-
-
52449095361
-
The RSK family of kinases: Emerging roles in cellular signalling
-
Anjum R, Blenis J, (2008) The RSK family of kinases: Emerging roles in cellular signalling. Nat Rev Mol Cell Biol 9: 747-758.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 747-758
-
-
Anjum, R.1
Blenis, J.2
-
27
-
-
33746258750
-
A general strategy for creating "inactive-conformation" Abl inhibitors
-
Okram B, Nagle A, Adrian FJ, Lee C, Ren P, et al. (2006) A general strategy for creating "inactive-conformation" Abl inhibitors. Chem Biol 13: 779-786.
-
(2006)
Chem Biol
, vol.13
, pp. 779-786
-
-
Okram, B.1
Nagle, A.2
Adrian, F.J.3
Lee, C.4
Ren, P.5
-
28
-
-
13444270324
-
Identification of the first specific inhibitor of p90 Ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation
-
Smith JA, Poteet-Smith CE, Xu Y, Errington TM, Hecht SM, et al. (2005) Identification of the first specific inhibitor of p90 Ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation. Cancer Res 65: 1027-1034.
-
(2005)
Cancer Res
, vol.65
, pp. 1027-1034
-
-
Smith, J.A.1
Poteet-Smith, C.E.2
Xu, Y.3
Errington, T.M.4
Hecht, S.M.5
-
29
-
-
78650731409
-
The therapeutic implications of plasticity of the cancer stem cell phenotype
-
Leder K, Holland EC, Michor F, (2010) The therapeutic implications of plasticity of the cancer stem cell phenotype. PLoS One 5: e14366.
-
(2010)
PLoS One
, vol.5
-
-
Leder, K.1
Holland, E.C.2
Michor, F.3
-
30
-
-
55549106810
-
Alpha2ß1 integrin regulates lineage commitment in multipotent human colorectal cancer cells
-
Kirkland SC, Ying H, (2008) Alpha2ß1 integrin regulates lineage commitment in multipotent human colorectal cancer cells. J Biol Chem 283: 27612-27619.
-
(2008)
J Biol Chem
, vol.283
, pp. 27612-27619
-
-
Kirkland, S.C.1
Ying, H.2
-
31
-
-
61949193776
-
Integrins in mammary-stem-cell biology and breast-cancer progression-a role in cancer stem cells?
-
Pontier SM, Muller WJ, (2009) Integrins in mammary-stem-cell biology and breast-cancer progression-a role in cancer stem cells? J Cell Sci 122: 207-214.
-
(2009)
J Cell Sci
, vol.122
, pp. 207-214
-
-
Pontier, S.M.1
Muller, W.J.2
-
32
-
-
84862286978
-
Significance of CD44 and CD24 as cancer stem cell markers: an enduring ambiguity
-
Jaggupilli A, Elkord E, (2012) Significance of CD44 and CD24 as cancer stem cell markers: an enduring ambiguity. Clin Dev Immunol 2012: 1-11.
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 1-11
-
-
Jaggupilli, A.1
Elkord, E.2
-
33
-
-
84858608410
-
Cancer stem cells: Impact, heterogeneity, and uncertainty
-
Magee JA, Piskonova E, Morrison SJ, (2012) Cancer stem cells: Impact, heterogeneity, and uncertainty. Cancer Cell 21: 283-296.
-
(2012)
Cancer Cell
, vol.21
, pp. 283-296
-
-
Magee, J.A.1
Piskonova, E.2
Morrison, S.J.3
-
34
-
-
84870806564
-
EMT and MET in metastasis: Where are the cancer stem cells?
-
Brabletz T, (2012) EMT and MET in metastasis: Where are the cancer stem cells? Cancer Cell 22: 699-701.
-
(2012)
Cancer Cell
, vol.22
, pp. 699-701
-
-
Brabletz, T.1
-
35
-
-
73349139547
-
Cell fate decisions are specified by the dynamic ERK interactome
-
Kriegsheim Av, Baiocchi D, Birtwistle M, Sumpton D, Bienvenut W, et al. (2009) Cell fate decisions are specified by the dynamic ERK interactome. Nat Cell Biol 11: 1458-1466.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1458-1466
-
-
Kriegsheim, A.1
Baiocchi, D.2
Birtwistle, M.3
Sumpton, D.4
Bienvenut, W.5
-
36
-
-
66449108540
-
DNA fingerprinting of the NCI-60 cell line panel
-
Lorenzi PL, Reinhold WC, Varma S, Hutchinson AA, Pommier Y, et al. (2009) DNA fingerprinting of the NCI-60 cell line panel. Mol Cancer Ther 8: 713-724.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 713-724
-
-
Lorenzi, P.L.1
Reinhold, W.C.2
Varma, S.3
Hutchinson, A.A.4
Pommier, Y.5
-
37
-
-
0025854476
-
Morphometric and colorimetric analyses of human tumor cell line growth and drug sensitivity in soft agar culture
-
Alley MC, Pacula-Cox CM, Hursey ML, Rubinstein LR, Boyd MR, (1991) Morphometric and colorimetric analyses of human tumor cell line growth and drug sensitivity in soft agar culture. Cancer Res 51: 1247-1256.
-
(1991)
Cancer Res
, vol.51
, pp. 1247-1256
-
-
Alley, M.C.1
Pacula-Cox, C.M.2
Hursey, M.L.3
Rubinstein, L.R.4
Boyd, M.R.5
-
38
-
-
0001852317
-
-
Totowa, NJ: Human Press
-
Plowman J, Dykes DJ, Hollingshead M, Simpson-Herren L, Alley MC, editors (1997) Human tumor xenograft models in NCI Drug Development. Totowa, NJ: Human Press. 101-125 p.
-
(1997)
Human tumor xenograft models in NCI Drug Development
, pp. 101-125
-
-
Plowman, J.1
Dykes, D.J.2
Hollingshead, M.3
Simpson-Herren, L.4
Alley, M.C.5
-
39
-
-
0032863685
-
Intrinsic drug resistance in primary and metastatic renal cell carcinoma
-
Gamelin E, Mertins SD, Regis JT, Mickley L, Abati A, et al. (1999) Intrinsic drug resistance in primary and metastatic renal cell carcinoma. J Urol 162: 217-224.
-
(1999)
J Urol
, vol.162
, pp. 217-224
-
-
Gamelin, E.1
Mertins, S.D.2
Regis, J.T.3
Mickley, L.4
Abati, A.5
-
40
-
-
33746049159
-
Homology model of RSK2 N-terminal kinase domain, structure-based identification of novel RSK2 inhibitors, and preliminary common pharmacophore
-
Nguyen TL, Gussio R, Smith JA, Lannigan DA, Hecht SM, et al. (2006) Homology model of RSK2 N-terminal kinase domain, structure-based identification of novel RSK2 inhibitors, and preliminary common pharmacophore. Bioorg Med Chem 14: 6097-6105.
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 6097-6105
-
-
Nguyen, T.L.1
Gussio, R.2
Smith, J.A.3
Lannigan, D.A.4
Hecht, S.M.5
-
41
-
-
32844464076
-
Microarrays for the functional analysis of the chemical-kinase interactome
-
Horiuchi KY, Wang Y, Diamond SL, Ma H, (2006) Microarrays for the functional analysis of the chemical-kinase interactome. J Biomol Screen 11: 48-56.
-
(2006)
J Biomol Screen
, vol.11
, pp. 48-56
-
-
Horiuchi, K.Y.1
Wang, Y.2
Diamond, S.L.3
Ma, H.4
-
42
-
-
0019468220
-
Limiting dilution assays for the determination of immunocompetent cells frequencies I. Data analysis
-
Taswell C, (1981) Limiting dilution assays for the determination of immunocompetent cells frequencies I. Data analysis. J Immunol 126: 1614-1619.
-
(1981)
J Immunol
, vol.126
, pp. 1614-1619
-
-
Taswell, C.1
|