Autism spectrum disorders in IVF children: A national case-control study in Finland

Human Reproduction

Volumn 28, Issue 3, 2013, Pages 812-818

  Lehti, V ^a   Brown, A S ^b,c   Gissler, M ^a,d,e   Rihko, M ^a   Suominen, A ^a   Sourander, A ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b Columbia University ^*  (United States)

^c National Institute of Health and Welfare ^*  (United States)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^e NORDIC SCHOOL OF PUBLIC HEALTH   (Sweden)

Author keywords

assisted reproduction; autism; epidemiology; IVF outcome

Indexed keywords

ADOLESCENT; ARTICLE; ASPERGER SYNDROME; AUTISM; CASE CONTROL STUDY; CHILDHOOD DISEASE; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DISEASE ASSOCIATION; FEMALE; FERTILIZATION IN VITRO; FINLAND; HUMAN; MAJOR CLINICAL STUDY; MALE; RISK ASSESSMENT; RISK FACTOR; SOCIAL STATUS; TWINS;

EID: 84874287333     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/des430     Document Type: Article

References (36)

1. Baird G, Simonoff E, Pickles A, Chandler S, Loucas T, Meldrum D, Charman T. Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP). Lancet 2006;368: 210-215.
2. Basatemur E, Sutcliffe A. Follow-up of children born after ART. Placenta 2008;29 (Suppl. B): 135-140.
3. Dupont WD. Power calculations for matched case-control studies. Biometrics 1988;44: 1157-1168.
4. Ericson A, Nygren KG, Olausson PO, Källen B. Hospital care utilization of infants born after IVF. Hum Reprod 2002;17: 929-932.
5. Gardener H, Spiegelman D, Buka SL. Prenatal risk factors for autism: comprehensive meta-analysis. Br J Psychiatry 2009;195: 7-14.
6. Gissler M, Heino A. Assisted fertility treatments 2008-2009. Statistical report 8/2010. Helsinki, Finland: National Institute for Health and Welfare, 2010.
7. Gissler M, Klemetti R, Sevón T, Hemminki E. Monitoring of IVF birth outcomes in Finland: a data quality study. BMC Med Inform Decis Mak 2004;4: 3.
8. Glasson EJ, Bower C, Petterson B, de Klerk N, Chaney G, Hallmayer JF. Perinatal factors and the development of autism: a population study. Arch Gen Psychiatry 2004;61: 618-627.
9. Haglund NG, Källén KB. Risk factors for autism and Asperger syndrome. Perinatal factors and migration. Autism 2011;15: 163-183.
10. Hansen M, Bower C, Milne E, de Klerk N, Kurinczuk JJ. Assisted reproductive technologies and the risk of birth defects-a systematic review. Hum Reprod 2005;20: 328-338.
11. Helmerhorst FM, Perquin DA, Donker D, Keirse MJ. Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies. BMJ 2004;328: 261.
12. Hultman CM, Sparen P, Cnattingius S. Perinatal risk factors for infantile autism. Epidemiology 2002;13: 417-423.
13. Hvidtjorn D, Schieve L, Schendel D, Jacobsson B, Svaerke C, Thorsen P. Cerebral palsy, autism spectrum disorders, and developmental delay in children born after assisted conception: a systematic review and meta-analysis. Arch Pediatr Adolesc Med 2009;163: 72-83.
14. Hvidtjorn D, Grove J, Schendel D, Schieve LA, Svaerke C, Ernst E, Thorsen P. Risk of autism spectrum disorders in children born after assisted conception: a population-based follow-up study. J Epidemiol Community Health 2011;65: 497-502.
15. Jackson RA, Gibson KA, Wu YW, Croughan MS. Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis. Obstet Gynecol 2004;103: 551-563.
16. Klemetti R, Sevón T, Gissler M, Hemminki E. Health of children born as a result of in vitro fertilization. Pediatrics 2006;118: 1819-1827.
17. Klemetti R, Gissler M, Sevón T, Hemminki E. Resource allocation of in vitro fertilization: a nationwide register-based cohort study. BMC Health Serv Res 2007;7: 210.
18. Kolevzon A, Gross R, Reichenberg A. Prenatal and perinatal risk factors for autism: a review and integration of findings. Arch Pediatr Adolesc Med 2007;161: 326-333.
19. Lampi KM, Sourander A, Gissler M, Niemelä S, Peltonen L, VonWendt L. Validity of Finnish registry-based diagnoses of autism with the ADI-R-a brief report. Acta Paediatrica 2010;99: 1425-1428.
20. Lampi KM, Banerjee PN, Gissler M, Hinkka-Yli-Salomäki S, Huttunen J, Kulmala U, Lindroos J, Niemelä S, Rihko M, Ristkari T et al. Finnish Prenatal Study of Autism and Autism Spectrum Disorders (FIPS-A): overview and design. J Autism Dev Disord 2011;41: 1090-1096.
21. Lampi KM, Lehtonen L, Tran PL, Suominen A, Lehti V, Banerjee PN, Gissler M, Brown AS, Sourander A. Risk of autism spectrum disorders in low birth weight and small for gestational age infants. J Pediatr 2012;161: 830-836.
22. Latif AH, Williams WR. Diagnostic trends in autistic spectrum disorders in the South Wales valleys. Autism 2007;11: 479-487.
23. Lidegaard O, Pinborg A, Andersen AN. Imprinting diseases and IVF: Danish National IVF cohort study. Hum Reprod 2005;20: 950-954.
24. Ludwig M, Diedrich K. Follow-up of children born after assisted reproductive technologies. Reprod Biomed Online 2002;5: 317-322.
25. Ludwig AK, Sutcliffe AG, Diedrich K, Ludwig M. Post-neonatal health and development of children born after assisted reproduction: a systematic review of controlled studies. Eur J Obstet Gynecol Reprod Biol 2006; 127: 3-25.
26. Maimburg RD, Vaeth M. Do children born after assisted conception have less risk of developing infantile autism? Hum Reprod 2007;22: 1841-1843.
27. Middelburg KJ, Heineman MJ, Bos AF, Hadders-Algra M. Neuromotor, cognitive, language and behavioural outcome in children born following IVF or ICSI-a systematic review. Hum Reprod Update 2008;14: 219-231.
28. National Institute for Health and Welfare. Medical Birth Register, Unpublished statistics 2012.
29. Reddy UM, Wapner RJ, Rebar RW, Tasca RJ. Infertility, assisted reproductive technology, and adverse pregnancy outcomes: executive summary of a National Institute of Child Health and Human Development workshop. Obstet Gynecol 2007;109: 967-977.
30. Rimm AA, Katayama AC, Diaz M, Katayama KP. A meta-analysis of controlled studies comparing major malformation rates in IVF and ICSI infants with naturally conceived children. J Assist Reprod Genet 2004; 21: 437-443.
31. Statistics Finland. Classification of occupations. Handbook 14, Helsinki, Finland, 1987.
32. Statistics Finland. Classification of socioeconomic groups. Handbook 17, Helsinki, Finland, 1989.
33. Sutcliffe AG, Ludwig M. Outcome of assisted reproduction. Lancet 2007; 370: 351-359.
34. Wagenaar K, Huisman J, Cohen-Kettenis PT, Delemarre-van deWaal HA. An overview of studies on early development, cognition, and psychosocial well-being in children born after in vitro fertilization. J Dev Behav Pediatr 2008;29: 219-230.
35. Wilkins-Haug L. Assisted reproductive technology, congenital malformations, and epigenetic disease. Clin Obstet Gynecol 2008;51: 96-105.
36. Williams E, Thomas K, Sidebotham H, Emond A. Prevalence and characteristics of autistic spectrum disorders in the ALSPAC cohort. Dev Med Child Neurol 2008;50: 672-677.