Psychotropic Medications and Falls in Nursing Homes: A Cross-Sectional Study

Journal of the American Medical Directors Association

Volumn 14, Issue 3, 2013, Pages 213-217

  Olazarán, Javier ^a,b   Valle, Daniel ^c   Serra, José Antonio ^b   Cano, Pedro ^c   Muñiz, Ruben ^a  

^a Maria Wolff Foundation   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^c Sanitas Residencial   (Spain)

Author keywords

Fall; Injurious fall; Nursing home; Psychotropic medications

Indexed keywords

ANTIDEPRESSANT AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; BENZODIAZEPINE DERIVATIVE; CHOLINESTERASE INHIBITOR; MEMANTINE; NEUROLEPTIC AGENT;

AGED; ARTICLE; CROSS-SECTIONAL STUDY; DEMENTIA; DRUG HALF LIFE; FALLING; FEMALE; HEAD INJURY; HIP FRACTURE; HUMAN; MAJOR CLINICAL STUDY; MALE; NURSING HOME; PRESCRIPTION; PSYCHOPHARMACOLOGY;

EID: 84874265015     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2012.10.020     Document Type: Article

References (28)

1. Gaugler J.E., Duval S., Anderson K.A., Kane R.L. Predicting nursing home admission in the US: A meta-analysis. BMC Geriatr 2007, 7:13.
2. Seitz D., Purandare N., Conn D. Prevalence of psychiatric disorders among older adults in long-term care homes: A systematic review. Int Psychogeriatr 2010, 22:1025-1039.
3. Robles Castiñeiras A., Díaz Grávalos G.J., Reinoso Hermida S., et al. [Prevalence of neuropsychiatric symptoms and associated factors in institutionalised dementia patients: A multicenter cross-sectional study]. Rev Esp Geriatr Gerontol 2012, 47:96-101. [Article in Spanish].
4. García-Gollarte F., Baleriola-Júlvez J., Ferrero-López I., Cruz-Jentoft A.J. Inappropriate drug prescription at nursing home admission. J Am Med Dir Assoc 2012, 13:83.e9-83.e15.
5. Gallagher P., Ryan C., Byrne S., et al. STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment): Consensus validation. Int J Clin Pharmacol Ther 2008, 46:72-83.
6. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc 2012, 60:616-631. American Geriatrics Society 2012 Beers Criteria Update Expert Panel.
7. French D.D., Campbell R., Spehar A., et al. Drugs and falls in community-dwelling older people: A national veterans study. Clin Ther 2006, 28:619-630.
8. Hill K.D., Wee R. Psychotropic drug-induced falls in older people: A review of interventions aimed at reducing the problem. Drugs Aging 2012, 29:15-30.
9. Zecevic A.A., Chesworth B.M., Zaric G.S., et al. Estimating the cost of serious injurious falls in a Canadian acute care hospital. Can J Aging 2012, 31:139-147.
10. Snijders A.H., van de Warrenburg B.P., Giladi N., Bloem B.R. Neurological gait disorders in elderly people: Clinical approach and classification. Lancet Neurol 2007, 6:63-74.
11. Fonad E., Wahlin T.B., Winblad B., et al. Falls and fall risk among nursing home residents. J Clin Nurs 2008, 17:126-134.
12. Kallin K., Gustafson Y., Sandman P.O., Karlsson S. Drugs and falls in older people in geriatric care settings. Aging Clin Exp Res 2004, 16:270-276.
13. Whitney J., Close J.C., Jackson S.H., Lord S.R. Understanding risk of falls in people with cognitive impairment living in residential care. J Am Med Dir Assoc 2012, 13:535-540.
14. Mena M.A., de Yébenes J.G. Drug-induced parkinsonism. Expert Opin Drug Saf 2006, 5:759-771.
15. Gauthier S., Cummings J., Ballard C., et al. Management of behavioral problems in Alzheimer's disease. Int Psychogeriatr 2010, 22:346-372.
16. Chung K.A., Lobb B.M., Nutt J.G., Horak F.B. Effects of a central cholinesterase inhibitor on reducing falls in Parkinson disease. Neurology 2010, 75:1263-1269.
17. Gill S.S., Anderson G.M., Fischer H.D., et al. Syncope and its consequences in patients with dementia receiving cholinesterase inhibitors: A population-based cohort study. Arch Intern Med 2009, 169:867-873.
18. Kim D.H., Brown R.T., Ding E.L., et al. Dementia medications and risk of falls, syncope, and related adverse events: Meta-analysis of randomized controlled trials. J Am Geriatr Soc 2011, 59:1019-1031.
19. Lobo A., Saz P., Marcos G., et al. [Revalidation and standardization of the cognition mini-exam (first Spanish version of the Mini-Mental Status Examination) in the general geriatric population]. Med Clin (Barc) 1999, 112:767-774. [Article in Spanish].
20. Folstein M.F., Folstein S.E., McHugh P.R. Mini-mental state: A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975, 12:189-198.
21. Matthews F.E., Dening T. UK Medical Research Council Cognitive Function and Ageing Study. Prevalence of dementia in institutional care. Lancet 2002, 360:225-226.
22. Fonad E., Emami A., Wahlin T.B., et al. Falls in somatic and dementia wards at Community Care Units. Scand J Caring Sci 2009, 23:2-10.
23. Jeste D.V., Blazer D., Casey D., et al. ACNP white paper: Update on use of antipsychotic drugs in elderly persons with dementia. Neuropsychopharmacology 2008, 33:957-970.
24. Ljunggren G., Phillips C.D., Sgadari A. Comparisons of restraint use in nursing homes in 8 countries. Age Ageing 1997, 26:43-47.
25. Thurman D.J., Stevens J.A., Rao J.K. Quality Standards Subcommittee of the American Academy of Neurology. Practice parameter: Assessing patients in a neurology practice for risk of falls (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2008, 70:473-479.
26. Majic T, Pluta JP, Mell T, et al. MA. The pharmacotherapy of neuropsychiatric symptoms of dementia: A cross-sectional study in 18 homes for the elderly in Berlin. Dtsch Arztebl Int 2010;107:320-327.
27. Olazarán J., Agüera-Ortiz L., Osorio R.S., et al. Promoting research in advanced dementia: Early clinical results of the Alzheimer Center Reina Sofía Foundation. J Alzheimers Dis 2012, 28:211-222.
28. Billioti de Gage S., Bégaud B., Bazin F., et al. Benzodiazepine use and risk of dementia: Prospective population-based study. BMJ 2012, 345:e6231.