Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 8, 2013, Pages 3023-3028

  Hiramoto, Takafumi ^a,b   Ebihara, Yasuhiro ^b   Mizoguchi, Yoko ^c   Nakamura, Kazuhiro ^c   Yamaguchi, Kiyoshi ^b   Ueno, Kazuko ^d   Nariai, Naoki ^d   Mochizuki, Shinji ^b   Yamamoto, Shohei ^b   Nagasaki, Masao ^d   Furukawa, Yoichi ^b   Tani, Kenzaburo ^a   Nakauchi, Hiromitsu ^b   Kobayashi, Masao ^c   Tsuji, Kohichiro ^b  

^a KYUSHU UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

^d TOHOKU UNIVERSITY   (Japan)

Author keywords

Apoptosis; SCN disease model; Unfolded protein response

Indexed keywords

BETA CATENIN; GRANULOCYTE COLONY STIMULATING FACTOR; LYMPHOID ENHANCER FACTOR 1; WNT3A PROTEIN;

ARTICLE; CELL MATURATION; CONTROLLED STUDY; GENE EXPRESSION; GRANULOPOIESIS; HUMAN; HUMAN CELL; NEUTROPHIL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SEVERE CONGENITAL NEUTROPENIA; SIGNAL TRANSDUCTION;

CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; LEUKOCYTE ELASTASE; MUTATION; NEUTROPENIA; NEUTROPHILS; PLURIPOTENT STEM CELLS; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; WNT3A PROTEIN;

EID: 84874256711     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1217039110     Document Type: Article

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