Negative Correlation of LIV-1 and E-Cadherin Expression in Hepatocellular Carcinoma Cells

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Shen, Rongxi ^a   Xie, Feng ^a   Shen, Hui ^a   liu, Qu ^a   Zheng, Tao ^a   Kou, Xingrui ^a   Wang, Dexian ^a   Yang, Jiamei ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN LIV 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; UVOMORULIN; ZINC TRANSPORTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOMA CELL; CELL GROWTH; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION; WESTERN BLOTTING;

AGED; ANIMALS; CADHERINS; CARCINOMA, HEPATOCELLULAR; CATION TRANSPORT PROTEINS; CELL ADHESION; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MICE; MIDDLE AGED; NEOPLASM PROTEINS; RNA, SMALL INTERFERING;

EID: 84874252681     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056542     Document Type: Article

References (20)

1. Taylor KM, Morgan HE, Johnson A, Hadley LJ, Nicholson RI, et al. (2003) Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters. Biochem J 375: 51-59.
2. Vallee BL, Falchuk KH, (1993) The biochemical basis of zinc physiology. Physiol Rev 73: 79-118.
3. Cousins RJ, (1998) A role of zinc in the regulation of gene expression.Proc Nutr Soc. 57: 307-311.
4. Manning DL, Daly RJ, Lord PG, Kelly KF, Green CD, (1988) Effects of oestrogen on the expression of a 4.4 kb mRNA in the ZR-75-1 human breast cancer cell line. Mol Cell Endocrinol 59: 205-212.
5. Manning DL, Robertson JF, Ellis IO, Elston CW, McClelland RA, et al. (1994) Oestrogen-regulated genes in breast cancer: association of pLIV1 with lymph node involvement. Eur J Cancer 30: 675-678.
6. Thiery JP, (2002) Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2: 442-454.
7. Petersen OW, Nielsen HL, Gudjonsson T, Villadsen R, Rank F, et al. (2003) Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma. Am J Pathol 162: 391-402.
8. Taylor KM, Hiscox S, Nicholson RI, (2004) Zinc transporter LIV-1: a link between cellular development and cancer progression. Trends Endocrinol Metab 15: 461-463.
9. Yamashita S, Miyagi C, Fukada T, Kagara N, Che YS, et al. (2004) Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer. Nature 429: 298-302.
10. Zhao L, Chen W, Taylor KM, Cai B, Li X, (2007) LIV-1 suppression inhibits HeLa cell invasion by targeting ERK1/2-Snail/Slug pathway. Biochem Biophys Res Commun 363: 82-88.
11. Parkin DM, Bray F, Ferlay J, Pisani P, (2005) Global cancer statistics, 2002.CA Cancer J Clin. 55: 74-108.
12. Kamangar F, Dores GM, Anderson WF, (2006) Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world.J Clin Oncol. 24: 2137-2150.
13. Zhao L, Chen W, Li X, (2007) Expression of LIV-1 mRNA in human cervical carcinoma and endometrial carcinoma. Nan Fang Yi Ke Da Xue Xue Bao 27: 1590-1592.
14. Unno J, Satoh K, Hirota M, Kanno A, Hamada S, et al. (2009) LIV-1 enhances the aggressive phenotype through the induction of epithelial to mesenchymal transition in human pancreatic carcinoma cells. Int J Oncol 35: 813-821.
15. Lue HW, Yang X, Wang R, Qian W, Xu RZ, et al. (2011) LIV-1 Promotes Prostate Cancer Epithelial-to-Mesenchymal Transition and Metastasis through HB-EGF Shedding and EGFR-Mediated ERK Signaling. PLOS ONE 6(11): e27720.
16. Kasper G, Weiser AA, Rump A, Sparbier K, Dahl E, et al. (2005) Expression levels of the putative zinc transporter LIV-1 are associated with a better outcome of breast cancer patients. Int J Cancer 117: 961-973.
17. Shiozaki H, Oka H, Inoue M, Tamura S, Monden M, et al. (1996) E-cadherin mediated adhesion system in cancer cells. Cancer 77: 1605-1613.
18. Bukholm IK, Nesland JM, Karesen R, Jacobsen U, Borresen-Dale AL, et al. (1998) E-cadherin and a-, b-, and c-catenin protein expression in relation to metastasis in human breast carcinoma. J Pathol 185: 262-266.
19. Van Aken E, De Wever O, Correia da Rocha AS, Mareel M, (2001) Defective E-cadherin/catenin complexes in human cancer.Virchows Arch. 439: 725-751.
20. Shen H, Qin H, Guo J, (2009) Concordant correlation of LIV-1 and E-cadherin expression in human breast cancer cell MCF-7. Mol Biol Rep 36: 653-659.