Lower molecular weight intravenous iron dextran for restless legs syndrome

Sleep Medicine

Volumn 14, Issue 3, 2013, Pages 274-277

  Cho, Yong Won ^a   Allen, Richard P ^b   Earley, Christopher J ^b  

^a Dongsan Medical Center   (South Korea)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebrospinal fluid; Ferritin; Iron dextran; Restless legs syndrome; Therapy

Indexed keywords

FERRITIN; IRON; IRON DEXTRAN;

ADULT; ARTICLE; BLOOD SAMPLING; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID ANALYSIS; CLINICAL ARTICLE; DRUG EFFICACY; ETHNIC GROUP; FEMALE; FOLLOW UP; HUMAN; IDIOPATHIC DISEASE; IRON BLOOD LEVEL; IRON THERAPY; KOREAN; MALE; MEDICAL PARAMETERS; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; RESTLESS LEGS SYNDROME; SCORING SYSTEM; SYMPTOMATOLOGY; TREATMENT DURATION; TREATMENT RESPONSE;

BRAIN; BRAIN CHEMISTRY; DRUG ADMINISTRATION SCHEDULE; FEMALE; FERRITINS; HEMATINICS; HUMANS; INJECTIONS, INTRAVENOUS; IRON-DEXTRAN COMPLEX; MALE; MIDDLE AGED; MOLECULAR WEIGHT; RESTLESS LEGS SYNDROME; TREATMENT OUTCOME;

EID: 84874246999     PISSN: 13899457     EISSN: 18785506     Source Type: Journal    
DOI: 10.1016/j.sleep.2012.11.001     Document Type: Article

References (20)

1. Allen R.P., Picchietti D., Hening W.A., Trenkwalder C., Walters A.S., Montplaisi J. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 2003, 4:101-119.
2. Sun E.R., Chen C.A., Ho G., Earley C.J., Allen R.P. Iron and the restless legs syndrome. Sleep 1998, 21:371-377.
3. Clardy S.L., Wang X., Boyer P.J., Earley C.J., Allen R.P., Connor J.R. Is ferroportin-hepcidin signaling altered in restless legs syndrome?. J Neurol Sci 2006, 247:173-179.
4. Connor J.R., Boyer P.J., Menzies S.L., Dellinger B., Allen R.P., Ondo W.G., et al. Neuropathological examination suggests impaired brain iron acquisition in restless legs syndrome. Neurology 2003, 61:304-309.
5. Earley C.J., Connor J.R., Beard J.L., Malecki E.A., Epstein D.K., Allen R.P. Abnormalities in CSF concentrations of ferritin and transferrin in restless legs syndrome. Neurology 2000, 54:1698-1700.
6. Earley C.J., Barker P.B., Horska A., Allen R.P. MRI-determined regional brain iron concentrations in early- and late-onset restless legs syndrome. Sleep Med 2006, 7:458-461.
7. Godau J., Klose U., Di Santo A., Schweitzer K., Berg D. Multiregional brain iron deficiency in restless legs syndrome. Mov Disord 2008, 23:1184-1187.
8. Mizuno S., Mihara T., Miyaoka T., Inagaki T., Horiguchi J. CSF iron, ferritin and transferrin levels in restless legs syndrome. J Sleep Res 2005, 14:43-47.
9. Earley C.J., Heckler D., Allen R.P. The treatment of restless legs syndrome with intravenous iron dextran. Sleep Med 2004, 5:231-235.
10. Nordlander N.B. Therapy in restless legs. Acta Med Scand 1953, 145:453-457.
11. Ondo W.G. Intravenous iron dextran for severe refractory restless legs syndrome. Sleep Med 2010, 11:494-496.
12. Parrow A., Werner I. The treatment of restless legs. Acta Med Scand 1966, 180:401-406.
13. Grote L., Leissner L., Hedner J., Ulfberg J. A randomized, double-blind, placebo controlled, multi-center study of intravenous iron sucrose and placebo in the treatment of restless legs syndrome. Mov Disord 2009, 24:1445-1452.
14. Earley C.J., Horska A., Mohamed M.A., Barker P.B., Beard J.L., Allen R.P. A randomized, double-blind, placebo-controlled trial of intravenous iron sucrose in restless legs syndrome. Sleep Med 2009, 10:206-211.
15. Allen R.P., Adler C.H., Du W., Butcher A., Bregman D.B., Earley C.J. Clinical efficacy and safety of IV ferric carboxymaltose (FCM) treatment of RLS: a multi-centred, placebo-controlled preliminary clinical trial. Sleep Med 2011, 12:906-913.
16. Cho Y., Lee M., Yun C., Shin W., Hong S., Kim J. The reliability and validity of the Korean version of paradigm of questions for epidemiology studies of RLS and the Johns Hopkins telephone diagnostic interview form for the RLS. J Korean Neurol Assoc 2007, 25:494-499.
17. Perlis ML, Jungquist C, Smith MT, Posner D The cognitive behavioral treatment of insomnia: a session-by-session guide 2005, Springer-Verlag, New York.
18. Yang J., Kim D., Lee J., Park K., Jung K., Shin W., et al. The reliability and validity of the Korean versions of the international restless legs scale and the restless legs syndrome quality of life questionnaire. J Korean Neurol Assoc 2010, 28:263-269.
19. Trenkwalder C., Benes H., Poewe W., Oertel W.H., Garcia-Borreguero D., de Weerd A.W., et al. Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trial. Lancet Neurol 2008, 7:595-604.
20. Connor J.R. Pathophysiology of restless legs syndrome: evidence for iron involvement. Curr Neurol Neurosci Rep 2008, 8:162-166.