Where Have All the Parasites Gone? Modelling Early Malaria Parasite Sequestration Dynamics

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Cromer, Deborah ^a   Best, Shannon E ^b   Engwerda, Christian ^b   Haque, Ashraful ^b   Davenport, Miles ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EARLY MALARIA PARASITE SEQUESTRATION DYNAMICS; ERYTHROCYTE PARAMETERS; FEMALE; GROWTH RATE; INFECTED RED BLOOD CELL; MATHEMATICAL MODEL; MOUSE; NONHUMAN; PARASITE CLEARANCE; PARASITE LOAD; PARASITE PHENOMENA AND FUNCTIONS; PARASITE VIRULENCE; PARASITEMIA;

ALGORITHMS; ANIMALS; DISEASE MODELS, ANIMAL; ERYTHROCYTES; FEMALE; LIFE CYCLE STAGES; MALARIA; MICE; MODELS, BIOLOGICAL; PARASITEMIA; PLASMODIUM BERGHEI; TIME FACTORS;

EID: 84874169977     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055961     Document Type: Article

References (36)

1. WHO (2010) Guidelines for the treatment of malaria. Second edition.
2. MacPherson GG, Warrell MJ, White NJ, Looareesuwan S, Warrell DA, (1985) Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration. Am J Pathol 119: 385-401.
3. Newton CR, Hien TT, White N, (2000) Cerebral malaria. J Neurol Neurosurg Psychiatr 69: 433-441.
4. Dondorp A, Desakorn V, Pongtavornpinyo W, Sahassananda D, Silamut K, et al. (2005) Estimation of the total parasite biomass in acute falciparum malaria from plasma PfHRP2. PLoS Med 2: e204.
5. Amante FH, Haque A, Stanley AC, Rivera FdL, Randall LM, et al. (2010) Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria. J Immunol 185: 3632-3642.
6. Franke-Fayard B, Janse C, Cunha-Rodrigues M, Ramesar J, Büscher P, et al. (2005) Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. Proc Natl Acad Sci USA 102: 11468-11473.
7. Chang WL, Jones SP, Lefer DJ, Welbourne T, Sun G, et al. (2001) CD8(+)-T-cell depletion ameliorates circulatory shock in Plasmodium berghei-infected mice. Infect Immun 69: 7341-7348.
8. Lovegrove FE, Gharib SA, Peña-Castillo L, Patel SN, Ruzinski JT, et al. (2008) Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model. PLoS Pathog 4: e1000068.
9. Haque A, Best SE, Amante FH, Ammerdorffer A, de Labastida F, et al. (2011) High parasite burdens cause liver damage in mice following Plasmodium berghei ANKA infection independently of CD8(+) T cell-mediated immune pathology. Infect Immun 79: 1882-1888.
10. Neill AL, Hunt NH, (1992) Pathology of fatal and resolving Plasmodium berghei cerebral malaria in mice. Parasitology 105 (Pt 2): 165-175.
11. Franke-Fayard B, Janse CJ, Cunha-Rodrigues M, Ramesar J, Büscher P, et al. (2005) Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. Proc Natl Acad Sci USA 102: 11468-11473.
12. Haque A, Best SE, Unosson K, Amante FH, de Labastida F, et al. (2011) Granzyme B Expression by CD8+ T Cells Is Required for the Development of Experimental Cerebral Malaria. J Immunol 186: 6148-6156.
13. Baptista FG, Pamplona A, Pena AC, Mota MM, Pied S, et al. (2010) Accumulation of Plasmodium berghei-infected red blood cells in the brain is crucial for the development of cerebral malaria in mice. Infect Immun 78: 4033-4039.
14. Silamut K, White NJ, (1993) Relation of the stage of parasite development in the peripheral blood to prognosis in severe falciparum malaria. Trans R Soc Trop Med Hyg 87: 436-443.
15. Fonager J, Pasini EM, Braks JAM, Klop O, Ramesar J, et al. (2011) Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo. The Journal of experimental medicine.
16. Jakeman G, Saul A, Hogarth W, Collins W, (1999) Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes. Parasitology 119 (Pt 2): 127-133.
17. Cromer D, Evans K, Schofield L, Davenport M, (2006) Preferential invasion of reticulocytes during late-stage Plasmodium berghei infection accounts for reduced circulating reticulocyte levels. Int J Parasitol 36: 1389-1397.
18. Miller M, Råberg L, Read A, Savill N (2010) Quantitative analysis of immune response and erythropoiesis during rodent malarial infection. PLoS Comput Biol 6.
19. White NJ, Chapman D, Watt G, (1992) The effects of multiplication and synchronicity on the vascular distribution of parasites in falciparum malaria. Trans R Soc Trop Med Hyg 86: 590-597.
20. Gravenor M, van Hensbroek M, Kwiatkowski D, (1998) Estimating sequestered parasite population dynamics in cerebral malaria. Proc Natl Acad Sci USA 95: 7620-7624.
21. Smith T, Dietz K, Vounatsou P, Muller I, English M, et al. (2004) Bayesian age-stage modelling of Plasmodium falciparum sequestered parasite loads in severe malaria patients. Parasitology 129: 289-299.
22. Antia R, Yates A, de Roode J, (2008) The dynamics of acute malaria infections. I. Effect of the parasite's red blood cell preference. Proc Biol Sci 275: 1449-1458.
23. Hetzel C, Anderson R, (1996) The within-host cellular dynamics of bloodstage malaria: theoretical and experimental studies. Parasitology 113 (Pt 1): 25-38.
24. Anderson R, May R, Gupta S, (1989) Non-linear phenomena in host-parasite interactions. Parasitology 99Suppl: S59-79.
25. Amante FH, Stanley AC, Randall LM, Zhou Y, Haque A, et al. (2007) A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria. Am J Pathol 171: 548-559.
26. Malleret B, Claser C, Ong ASM, Suwanarusk R, Sriprawat K, et al. (2011) A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development. Scientific Reports 1: 118.
27. Ochola L, Marsh K, Lowe B, Gal S, Pluschke G, et al. (2005) Estimation of the sequestered parasite load in severe malaria patients using both host and parasite markers. Parasitology 131: 449-458.
28. Hellriegel B, (1992) Modelling the immune response to malaria with ecological concepts: short-term behaviour against long-term equilibrium. Proc R Soc Lond B Biol Sci 250: 249-256.
29. Hoshen M, Heinrich R, Stein W, Ginsburg H, (2000) Mathematical modelling of the within-host dynamics of Plasmodium falciparum. Parasitology 121 (Pt 3): 227-235.
30. Franke-Fayard B, Fonager J, Braks A, Khan S, Janse C (2010) Sequestration and tissue accumulation of human malaria parasites: can we learn anything from rodent models of malaria? PLoS Pathog 6.
31. Craig AG, Grau GE, Janse C, Kazura JW, Milner D, et al. (2012) The role of animal models for research on severe malaria. PLoS Pathog 8: e1002401.
32. Perelson A, Nelson P, (1999) Mathematical Analysis of HIV-1 Dynamics in Vivo. SIAM Review 41: 3-44.
33. Perelson A, Neumann A, Markowitz M, Leonard J, Ho D, (1996) HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science 271: 1582-1586.
34. Phillips A, (1996) Reduction of HIV concentration during acute infection: independence from a specific immune response. Science 271: 497-499.
35. Mideo N, Barclay V, Chan B, Savill N, Read A, et al. (2008) Understanding and predicting strain-specific patterns of pathogenesis in the rodent malaria Plasmodium chabaudi. Am Nat 172: 214-238.
36. Mons B, Janse C, Boorsma E, Van der Kaay H, (1985) Synchronized erythrocytic schizogony and gametocytogenesis of Plasmodium berghei in vivo and in vitro. Parasitology 91 (Pt 3): 423-430.