Increased Drinking following Social Isolation Rearing: Implications for Polydipsia Associated with Schizophrenia

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Hawken, Emily R ^a,b   Delva, Nicholas J ^b,c   Beninger, Richard J ^a,b  

^a QUEEN S UNIVERSITY   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

^c DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DRINKING BEHAVIOR; FLUID INTAKE; MALE; NONHUMAN; POLYDIPSIA; POST WEANING; RAT; REARING; SCHIZOPHRENIA; SOCIAL ISOLATION; WEANING;

ANIMALS; DIZOCILPINE MALEATE; DRINKING; MALE; POLYDIPSIA; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SCHIZOPHRENIA; SOCIAL ISOLATION;

EID: 84874128018     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056105     Document Type: Article

References (55)

1. de Leon J, Verghese C, Tracy J, Josiassen R, Simpson GM, (1994) Polydipsia and water intoxication in psychiatric patients: A review of the epidemiological literature. Biol Psychiatry 35: 408-19.
2. Torres IJ, Keedy S, Marlow-O'Connor M, Beenken B, Goldman MB, (2009) Neuropsychological impairment in patients with schizophrenia and evidence of hyponatremia and polydipsia. Neuropsychology 23: 307-14.
3. Poirier S, Legris G, Tremblay P, Michea R, Viau-Guay L, et al. (2010) Schizophrenia patients with polydipsia and water intoxication are characterized by greater severity of psychotic illness and more frequent history of alcohol abuse. Schizophr Res 118: 285-91.
4. Hawken ER, Crookall JM, Reddick D, Millson RC, Milev R, et al. (2009) Mortality over a 20-year period in patients with primary polydipsia associated with schizophrenia: a retrospective study. Schizophr Res 107: 128-33.
5. Umbricht D, (1994) Polydipsia and hippocampal pathology. Biol Psychiatry 36: 708-10.
6. Goldman MB, Torres IJ, Keedy S, Marlow-O'Connor M, Beenken B, et al. (2007) Reduced anterior hippocampal formation volume in hyponatremic schizophrenic patients. Hippocampus 17: 554-62.
7. Goldman MB, Wood G, Goldman MB, Gavin M, Paul S, et al. (2007) Diminished glucocorticoid negative feedback in polydipsic hyponatremic schizophrenic patients. J Clin Endocrinol Metab 92: 698-704.
8. Nettles KW, Pesold C, Goldman MB, (2000) Influences of the ventral hippocampal formation on plasma vasopressin, hypothalamic-pituitary-adrenal axis, and behavioral responses to novel acoustic stress. Brain Res 858: 181-90.
9. Herman JP, Ostrander MM, Mueller NK, Figueiredo H, (2005) Limbic system mechanisms of stress regulation: hypothalamo-pituitary-adrenocortical axis. Prog Neuro-psychopharmacol Biol Psychiaty 29: 1201-13.
10. Goldman MB, Wang L, Wachi C, Daudi S, Csernansky J, et al. (2011) Structural pathology underlying neuroendocrine dysfunction in schizophrenia. Behav Brain Res 218: 106-13.
11. Goldman MB, Mitchell CP, (2004) What is the functional significance of hippocampal pathology in schizophrenia? Schizophr Bull 30: 367-92.
12. Harrison PJ, (2004) The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications. Psychopharmacology (Berl) 174: 151-62.
13. Dawe GS, Hwang EH, Tan CH, (2009) Pathophysiology and animal models of schizophrenia. Ann Acad Med Singapore 38: 425-26.
14. Beninger RJ, Forsyth JK, Adel MV, Reynolds JN, Boegman RJ, et al. (2009) Subchronic MK-801 deficits in rats: Partial reversal by the novel nitrate GT 1061. Pharmacol Biochem Behav 91: 495-502.
15. Jentsch JD, Roth RH, (1999) The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia. Neuropsychopharmacology 20: 201-25.
16. Braun I, Genius J, Grunze H, Bender A, Möller HJ, et al. (2007) Alterations of hippocampal and prefrontal GABAergic interneurons in an animal model of psychosis induced by NMDA receptor antagonism. Schizophr Res 97: 254-63.
17. Falk JL, (1966) Schedule-induced polydipsia as a function of fixed interval length. J Exp Anal Behav 9: 37-9.
18. Hawken ER, Delva NJ, Reynolds JN, Beninger RJ, (2011) Increased schedule-induced polydipsia in the rat following subchronic treatment with MK-801. Schizophr Res 125: 93-8.
19. Powell CM, Miyakawa T, (2006) Schizophrenia-relevant behavioral testing in rodent models: a uniquely human disorder? Biol Psychiatry 59: 1198-207.
20. Einon D, Morgan MJ, (1977) A critical period for social isolation in the rat. Dev Psychobiol 10: 123-132.
21. Einon D, Morgan MJ, (1978) Early isolation produces enduring hyperactivity in the rat, but no effects on spontaneous alternation. Q J Exp Psychol 30: 151-156.
22. Wilkinson LS, Killcross SS, Humby T, Hall FS, Geyer MA, et al. (1994) Social isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response without disrupting latent inhibition. Neuropsychopharmacology 10: 63-72.
23. Fone KC, Porkess MV, (2008) Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders. Neurosci Biobehav Rev 32: 1087-102.
24. Hickey AJ, Reynolds JN, Beninger RJ, (2012) Post-weaning social isolation and subchronic NMDA glutamate receptor blockage: effects on locomotor activity and GABA signaling in the rat suggest independent mechanisms. Pharmacol Biochem Behav 101: 231-8.
25. Flory RK, (1971) The control of schedule induced polydipsia: frequency and magnitude of reinforcement. Learn Motiv 2: 215-227.
26. Falk JL, (1971) The nature and determinants of adjunctive behavior. Physiol Behav 6: 577-88.
27. Wallace M, Singer G, (1976) Schedule induced behavior: a review of its generality, determinants and pharmacological data. Pharmacol Biochem Behav 5: 483-90.
28. van den Heave OA, van der Werf YD, Verhoef KM, de Wit S, Berendse HW, et al. (2010) Frontal-striatal abnormalities underlying behaviours in the compulsive-impulsive spectrum. J Neurol Sci 289: 55-9.
29. Woods A, Smith C, Szewczak M, Dunn RW, Cornfeldt M, et al. (1993) Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder. Psychopharmacology (Berl) 112: 195-8.
30. Platt B, Beyer CE, Schechter LE, Rosenzweig-Lipson S (2008) Schedule-induced polydipsia: a rat model of obsessive-compulsive disorder. Curr Protoc Neurosci Apr; Chapter 9, Unit 9.27.
31. Moreno M, Flores P, (2012) Schedule-induced polydipsia as a model of compulsive behavior: neuropharmacological and neuroendocrine bases. Psychopharmacology (Berl). 219: 647-59.
32. Luchins DJ, Goldman MB, Lieb M, Hanrahan P, (1992) Repetitive behaviors in chronically institutionalized schizophrenic patients. Schizophr Res 8: 119-23.
33. Byerly M, Goodman W, Acholonu W, Bugno R, Rush AJ, (2005) Obsessive-compulsive symptoms in schizophrenia: frequency and clinical features. Schizophr Res 76: 309-316.
34. Cunill R, Castells X, Simeon D, (2009) Relationships between obsessive-compulsive symptomaloty and severity of psychosis in schizophrenia: a systematic review and meta-analysis. J Clin Psychiatry 70: 70-82.
35. Lysaker PH, Whitney KA, (2009) Obsessive-compulsive symptoms in schizophrenia: prevalence, correlates and treatment. Expert Rev Neurother 9: 99-107.
36. Cassano GB, Pini S, Saettoni M, Rucci P, Dell'Osso L, (1998) Occurrence and clinical correlates of psychiatric comorbidity in patients with psychotic disorders. J Clin Psychiatry 59: 60-8.
37. Poyurovsky M, Fuchs C, Weizman A, (1999) Obsessive-compulsive disorder in patients with first-episode schizophrenia. Am J Psychiatry 156: 1998-2000.
38. Mittleman G, Rosner AL, Schaub CL, (1994) Polydipsia and dopamine: behavioural effects of dopamine D1and D2 receptor agonists and antagonists. J Pharmacol Exp Ther 271: 638-50.
39. Escher T, Call SB, Blaha CD, Mittleman G, (2006) Behavioral effects of aminoadamantane class NMDA recptor antagonists on schedule-induced alcohol and self-administration of water in mice. Psychopharmacology (Berl) 187: 424-34.
40. Flores P, Pellón R, (1995) Rate-dependency hypothesis and the rate-decreasing effects of d-amphetamine on schedule-induced drinking. Behav Pharmacol 6: 16-23.
41. Lopez-Grancha M, Lopez-Crespo G, Sanchez-Amate MC, Flores P, (2008) Inividual differences in schedule-induced polydipsia and the role of gabaergic and dopaminergic systems. Psychopharmacology (Berl) 197: 487-98.
42. Pellón R, Ruíz A, Moreno M, Claro F, Ambrosio E, et al. (2011) Individual differences in schedule-induced polydipsia: Neuroanatomical dopamine divergences. Behav Brain Res 217: 195-201.
43. Fabricius K, Helboe L, Fink-Jensen A, Wörtwein G, Steiniger-Brach B, et al. (2010) Increased dopaminergic activity in socially isolated rats: an electrophysilogical study. Neurosci Lett 482: 117-22.
44. Lodge DJ, Grace AA, (2008) Hippocampal dysfunction and disruption of dopamine system regulation in an animal model of schiozphrenia. Neurotox Res 14: 97-104.
45. Alquier G, Morales-Medina JC, Quirion R, Flores G, (2008) Postweaning social isolation enhances morphological changes in the neonatal ventral hippocampal lesion rat model of psychosis. J Chem Neuroanat 35: 179-87.
46. Harte MK, Powell SB, Swerdlow NR, Geyer MA, Reynolds GP, (2007) Deficits in parvalbumin and calbindin immunoreactive cells in the hippocampus of isolation reared rats. J Neural Transm 114: 893-8.
47. Huang ZJ, (2009) Activity-dependent development of inhibitory synapses and innervation pattern: role of GABA signaling and beyond. J Physiol 587: 1881-8.
48. Belforte JE, Zsiros V, Sklar ER, Jiang Z, Yu G, et al. (2010) Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phyenotypes. Nat Neurosci 13: 76-83.
49. Lapiz MD, Fulford A, Muchimapura S, Mason R, Parker T, et al. (2003) Influence of postweaning social isolation in the rat on brain development, conditioned behavior and neurotransmission. Neurosci Behav Physiol 33: 13-29.
50. Simpson SM, Menard JL, Reynolds JN, Beninger RJ, (2010) Post-weaning social isolation increases activity in a novel environment but decreases defensive burying and subchronic MK-801 enhances the activity but not the burying effect in rats. Pharmacol Biochem Behav 95: 72-9.
51. Ashby DM, Habib D, Dringenberg HC, Reynolds JN, Beninger RJ, (2010) Subchronic MK-801 treatment and post-weaning social isolation in rats: differential effects on locomotor activity and hippocampal long-term potentiation. Behav Brain Res 212: 64-70.
52. Hooks MS, Jones GH, Juncos JL, Neill DB, Justice JB, (1994) Individual differences in schedule-induced and conditioned behaviours. Behav Brain Res 60: 199-209.
53. Jones GH, Robbins TW, Marsden CA, (1989) Isolation-rearing retards the acquisition of schedule-induced polydipsia in rats. Physiol Behav 45: 71-7.
54. Hong S, Flashner B, Chiu M, ver Hoeve E, Luz S, et al. (2012) Social isolation in adolescence alters behaviours in the forced swim and sucrose preference tests in female but not in male rats. Physiol Behav 105: 269-75.
55. Mercier-Guidez E, Loas G, (2000) Polydipsia and water intoxication in 353 psychiatric inpatients: an epidemiological and psychopathological study. Eur Psychiatry 15: 306-11.