Thyroid hormone is required for growth adaptation to pressure load in the ovine fetal heart

Experimental Physiology

Volumn 98, Issue 3, 2013, Pages 722-733

  Segar, Jeffrey L ^a   Volk, Ken A ^a   Lipman, Michael H B ^a   Scholz, Thomas D ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; THYROID HORMONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; FETUS; FETUS HEART; FETUS HEART RATE; FETUS WEIGHT; GENE EXPRESSION; GESTATIONAL AGE; HEART DEVELOPMENT; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; LUNG ARTERY BANDING; MEAN ARTERIAL PRESSURE; NONHUMAN; SHEEP; THYROIDECTOMY;

EID: 84874118285     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2012.069435     Document Type: Article

References (42)

1. Barbera A, Giraud GD, Reller MD, Maylie J, Morton MJ & Thornburg KL (2000). Right ventricular systolic pressure load alters myocyte maturation in fetal sheep. Am J Physiol Regul Integr Comp Physiol 279, R1157-R1164.
2. Belakavadi M, Saunders J, Weisleder N, Raghava PS & Fondell JD (2010). Repression of cardiac phospholamban gene expression is mediated by thyroid hormone receptor-α1 and involves targeted covalent histone modifications. Endocrinology 151, 2946-2956.
3. Bernardo BC, Weeks KL, Pretorius L & McMullen JR (2010). Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies. Pharmacol Ther 128, 191-227.
4. Bubb KJ, Cock ML, Black MJ, Dodic M, Boon WM, Parkington HC, Harding R & Tare M (2007). Intrauterine growth restriction delays cardiomyocyte maturation and alters coronary artery function in the fetal sheep. J Physiol 578, 871-881.
5. Chattergoon NN, Giraud GD, Louey S, Stork P, Fowden AL & Thornburg KL (2011). Thyroid hormone drives fetal cardiomyocyte maturation. FASEB J 26, 397-408.
6. Chattergoon NN, Giraud GD & Thornburg KL (2007). Thyroid hormone inhibits proliferation of fetal cardiac myocytes in vitro. J Endocrinol 192, R1-R8.
7. Chen K, Carey LC, Valego NK, Liu J & Rose JC (2005). Thyroid hormone modulates renin and ANG II receptor expression in fetal sheep. Am J Physiol Regul Integr Comp Physiol 289, R1006-R1014.
8. Corstius HB, Zimanyi MA, Maka N, Herath T, Thomas W, van der Laarse A, Wreford NG & Black MJ (2005). Effect of intrauterine growth restriction on the number of cardiomyocytes in rat hearts. Pediatr Res 57, 796-800.
9. Dalshaug GB, Scholz TD, Smith OM, Bedell KA, Caldarone CA & Segar JL (2002). Effects of gestational age on myocardial blood flow and coronary flow reserve in pressure-loaded ovine fetal hearts. Am J Physiol Heart Circ Physiol 282, H1359-H1369.
10. Dillmann W (2010). Cardiac hypertrophy and thyroid hormone signaling. Heart Fail Rev 15, 125-132.
11. Fraser M & Liggins GC (1988). Thyroid hormone kinetics during late pregnancy in the ovine fetus. J Dev Physiol 10, 461-471.
12. Giraud GD, Louey S, Jonker S, Schultz J & Thornburg KL (2006). Cortisol stimulates cell cycle activity in the cardiomyocyte of the sheep fetus. Endocrinology 147, 3643-3649.
13. Gopinathan L, Ratnacaram CK & Kaldis P (2011). Established and novel Cdk/cyclin complexes regulating the cell cycle and development. Results Probl Cell Differ 53, 365-389.
14. Haddad F, Jiang W, Bodell PW, Qin AX & Baldwin KM (2010). Cardiac myosin heavy chain gene regulation by thyroid hormone involves altered histone modifications. Am J Physiol Heart Circ Physiol 299, H1968-H1980.
15. Haddad F, Qin AX, Bodell PW, Jiang W, Giger JM & Baldwin KM (2008). Intergenic transcription and developmental regulation of cardiac myosin heavy chain genes. Am J Physiol Heart Circ Physiol 294, H29-H40.
16. Hopkins PS & Thorburn GD (1972). The effects of foetal thyroidectomy on the development of the ovine foetus. J Endocrinol 54, 55-66.
17. Jonker SS, Giraud MK, Giraud GD, Chattergoon NN, Louey S, Davis LE, Faber JJ & Thornburg KL (2010). Cardiomyocyte enlargement, proliferation and maturation during chronic fetal anaemia in sheep. Exp Physiol 95, 131-139.
18. Jonker SS, Zhang L, Louey S, Giraud GD, Thornburg KL & Faber JJ (2007). Myocyte enlargement, differentiation, and proliferation kinetics in the fetal sheep heart. J Appl Physiol 102, 1130-1142.
19. Kahaly GJ & Dillmann WH (2005). Thyroid hormone action in the heart. Endocr Rev 26, 704-728.
20. S6K pathways. J Biol Chem 281, 20666-20672.
21. Ledda-Columbano GM, Molotzu F, Pibiri M, Cossu C, Perra A & Columbano A (2006). Thyroid hormone induces cyclin D1 nuclear translocation and DNA synthesis in adult rat cardiomyocytes. FASEB J 20, 87-94.
22. Leeuwenburgh BP, Helbing WA, Wenink AC, Steendijk P, de Jong R, Dreef EJ, Gittenberger-de Groot AC, Baan J & van der Laarse A (2008). Chronic right ventricular pressure overload results in a hyperplastic rather than a hypertrophic myocardial response. J Anat 212, 286-294.
23. Li G, Bae S & Zhang L (2004). Effect of prenatal hypoxia on heat stress-mediated cardioprotection in adult rat heart. Am J Physiol Heart Circ Physiol 286, H1712-H1719.
24. Li G, Xiao Y, Estrella JL, Ducsay CA, Gilbert RD & Zhang L (2003). Effect of fetal hypoxia on heart susceptibility to ischemia and reperfusion injury in the adult rat. J Soc Gynecol Investig 10, 265-274.
25. Liu Q, Yan H, Dawes NJ, Mottino GA, Frank JS & Zhu H (1996). Insulin-like growth factor II induces DNA synthesis in fetal ventricular myocytes in vitro. Circ Res 79, 716-726.
26. Lumbers ER, Kim MY, Burrell JH, Kumarasamy V, Boyce AC, Gibson KJ, Gatford KL & Owens JA (2009). Effects of intrafetal IGF-I on growth of cardiac myocytes in late-gestation fetal sheep. Am J Physiol Endocrinol Metab 296, E513-E519.
27. Morrison JL, Botting KJ, Dyer JL, Williams SJ, Thornburg KL & McMillen IC (2007). Restriction of placental function alters heart development in the sheep fetus. Am J Physiol Regul Integr Comp Physiol 293, R306-R313.
28. Nishida K, Kyoi S, Yamaguchi O, Sadoshima J & Otsu K (2009). The role of autophagy in the heart. Cell Death Differ 16, 31-38.
29. Olson AK, Protheroe KN, Scholz TD & Segar JL (2006a). The mitogen-activated protein kinases and Akt are developmentally regulated in the chronically anemic fetal sheep heart. J Soc Gynecol Investig 13, 157-165.
30. Olson AK, Protheroe KN, Segar JL & Scholz TD (2006b). Mitogen-activated protein kinase activation and regulation in the pressure-loaded fetal ovine heart. Am J Physiol Heart Circ Physiol 290, H1587-H1595.
31. O'Tierney PF, Chattergoon NN, Louey S, Giraud GD & Thornburg KL (2010). Atrial natriuretic peptide inhibits angiotensin II-stimulated proliferation in fetal cardiomyocytes. J Physiol 588, 2879-2889.
32. Reini SA, Wood CE & Keller-Wood M (2009). The ontogeny of genes related to ovine fetal cardiac growth. Gene Expr Patterns 9, 122-128.
33. Segar JL, Dalshaug GB, Bedell KA, Smith OM & Scholz TD (2001). Angiotensin II in cardiac pressure-overload hypertrophy in fetal sheep. Am J Physiol Regul Integr Comp Physiol 281, R2037-R2047.
34. 1 receptor blockade fails to attenuate pressure-overload cardiac hypertrophy in fetal sheep. Am J Physiol 273, R1501-R1508.
35. Smolich JJ, Walker AM, Campbell GR & Adamson TM (1989). Left and right ventricular myocardial morphometry in fetal, neonatal, and adult sheep. Am J Physiol 257, H1-H9.
36. Sundgren NC, Giraud GD, Schultz JM, Lasarev MR, Stork PJ & Thornburg KL (2003a). Extracellular signal-regulated kinase and phosphoinositol-3 kinase mediate IGF-1 induced proliferation of fetal sheep cardiomyocytes. Am J Physiol Regul Integr Comp Physiol 285, R1481-R1489.
37. Sundgren NC, Giraud GD, Stork PJ, Maylie JG & Thornburg KL (2003b). Angiotensin II stimulates hyperplasia but not hypertrophy in immature ovine cardiomyocytes. J Physiol 548, 881-891.
38. Thornburg K, Jonker S, O'Tierney P, Chattergoon N, Louey S, Faber J & Giraud G (2011). Regulation of the cardiomyocyte population in the developing heart. Prog Biophys Mol Biol 106, 289-299.
39. Thorpe-Beeston JG, Nicolaides KH, Felton CV, Butler J & McGregor AM (1991). Maturation of the secretion of thyroid hormone and thyroid-stimulating hormone in the fetus. N Engl J Med 324, 532-536.
40. 2R expression and subsequent vulnerability to adult ischaemic injury. Cardiovasc Res 89, 300-308.
41. Yuan J, Yan R, Kramer A, Eckerdt F, Roller M, Kaufmann M & Strebhardt K (2004). Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells. Oncogene 23, 5843-5852.
42. Zhu H, Tannous P, Johnstone JL, Kong Y, Shelton JM, Richardson JA, Le V, Levine B, Rothermel BA & Hill JA (2007). Cardiac autophagy is a maladaptive response to hemodynamic stress. J Clin Invest 117, 1782-1793.