Does supplementation of in-vitro culture medium with melatonin improve IVF outcome in PCOS

Reproductive BioMedicine Online

Volumn 26, Issue 1, 2013, Pages 22-29

  Kim, Mi Kyoung ^a   Park, Eun A ^a   Kim, Hyung Joon ^a   Choi, Won Yun ^a   Cho, Jung Hyun ^a   Lee, Woo Sik ^a   Cha, Kwang Yul ^a   You Kim, Shin ^a   Lee, Dong Ryul ^a   Yoon, Tae Ki ^a  

^a CHA University   (South Korea)

Author keywords

Culture media; In vitro maturation; IVF; Melatonin; Oocyte maturation; PCOS

Indexed keywords

ACYLTRANSFERASE; ARALKYLAMINE ACETYLSEROTONIN O METHYLTRANSFERASE; CHORIONIC GONADOTROPIN; ESTRADIOL VALERATE; MELATONIN; METHYLTRANSFERASE; PROGESTERONE; RECOMBINANT FOLLITROPIN; TAIYU PROGESTERONE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CUMULUS CELL; CYTOPLASM; EMBRYO TRANSFER; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; GRANULOSA CELL; HUMAN; HUMAN CELL; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; NIDATION; NUCLEOTIDE SEQUENCE; OOCYTE; OOCYTE MATURATION; OOCYTE RETRIEVAL; OUTCOME ASSESSMENT; OVARY FOLLICLE; OVARY POLYCYSTIC DISEASE; PREGNANCY RATE; RANDOMIZED CONTROLLED TRIAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 84874112841     PISSN: 14726483     EISSN: 14726491     Source Type: Journal    
DOI: 10.1016/j.rbmo.2012.10.007     Document Type: Article

References (30)

1. Acuna-Castroviejo, D., Martin, M., Macias, M., Escames, G., Leon, J., Khaldy, H., Reiter, R.J., 2001. Melatonin, mitochondria, and cellular bioenergetics. J. Pineal Res. 30, 65-74.
2. Azziz, R., Woods, K.S., Reyna, R., Key, T.J., Knochenhauer, E.S., Yildiz, B.O., 2004. The prevalence and features of the polycystic ovary syndrome in an unselected population. J. Clin. Endocrinol. Metab. 89, 2745-2749.
3. Brzezinski, A., Seibel, M.M., Lynch, H.J., Deng, M.H., Wurtman, R.J., 1987. Melatonin in human preovulatory follicular fluid. J. Clin. Endocrinol. Metab. 64, 865-867.
4. Cha, K.Y., Chian, R.C., 1998. Maturation in vitro of immature human oocytes for clinical use. Hum. Reprod. Update 4, 103-120.
5. Cha, K.Y., Koo, J.J., Ko, J.J., Choi, D.H., Han, S.Y., Yoon, T.K., 1991. Pregnancy after in vitro fertilization of human follicular oocytes collected from nonstimulated cycles, their culture in vitro and their transfer in a donor oocyte program. Fertil. Steril. 55, 109-113.
6. Cha, K.Y., Han, S.Y., Chung, H.M., Choi, D.H., Lim, J.M., Lee, W.S., Ko, J.J., Yoon, T.K., 2000. Pregnancies and deliveries after in vitro maturation culture followed by in vitro fertilization and embryo transfer without stimulation in women with polycystic ovary syndrome. Fertil. Steril. 73, 978-983.
7. Cha, K.Y., Chung, H.M., Lee, D.R., Kwon, H., Chung, M.K., Park, L.S., Choi, D.H., Yoon, T.K., 2005. Obstetric outcome of patients with polycystic ovary syndrome treated by in vitro maturation and in vitro fertilization-embryo transfer. Fertil. Steril. 83, 1461-1465.
8. Chattoraj, A., Bhattacharyya, S., Basu, D., Bhattacharya, S., Maitra, S.K., 2005. Melatonin accelerates maturation inducing hormone (MIH): induced oocyte maturation in carps. Gen. Comp. Endocrinol. 140, 145-155.
9. Chian, R.C., Buckett, W.M., Too, L.L., Tan, S.L., 1999. Pregnancies resulting from in vitro matured oocytes retrieved from patients with polycystic ovary syndrome after priming with human chorionic gonadotropin. Fertil. Steril. 72, 639-642.
10. Chian, R.C., Buckett, W.M., Tulandi, T., Tan, S.L., 2000. Prospective randomized study of human chorionic gonadotrophin priming before immature oocyte retrieval from unstimulated women with polycystic ovarian syndrome. Hum. Reprod. 15, 165-170.
11. Combelles, C.M., Gupta, S., Agarwal, A., 2009. Could oxidative stress influence the in-vitro maturation of oocytes Reprod. Biomed. Online 18, 864-880.
12. El-Raey, M., Geshi, M., Somfai, T., Kaneda, M., Hirako, M., Abdel-Ghaffar, A.E., Sosa, G.A., El-Roos, M.E., Nagai, T., 2011. Evidence of melatonin synthesis in the cumulus oocyte complexes and its role in enhancing oocyte maturation in vitro in cattle. Mol. Reprod. Dev. 78, 250-262.
13. Harris, S.E., Maruthini, D., Tang, T., Balen, A.H., Picton, H.M., 2010. Metabolism and karyotype analysis of oocytes from patients with polycystic ovary syndrome. Hum. Reprod. 25, 2305-2315.
14. Kang, J.T., Koo, O.J., Kwon, D.K., Park, H.J., Jang, G., Kang, S.K., Lee, B.C., 2009. Effects of melatonin on in vitro maturation of porcine oocyte and expression of melatonin receptor RNA in cumulus and granulosa cells. J. Pineal Res. 46, 22-28.
15. Livak, K.J., Schmittgen, T.D., 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25, 402-408.
16. Nakamura, Y., Tamura, H., Takayama, H., Kato, H., 2003. Increased endogenous level of melatonin in preovulatory human follicles does not directly influence progesterone production. Fertil. Steril. 80, 1012-1016.
17. Plachot, M., Belaisch-Allart, J., Mayenga, J.M., Chouraqui, A., Tesquier, A., Serkine, A.M., Boujenah, A., Abirached, F., 2003. Oocyte and embryo quality in polycystic ovary syndrome. Gynecol. Obstet. Fertil. 31, 350-354.
18. Reiter, R.J., 1980. The pineal and its hormones in the control of reproduction in mammals. Endocr. Rev. 1, 109-131.
19. Reiter, R.J., 1991. Melatonin: the chemical expression of darkness. Mol. Cell. Endocrinol. 79, C153-C158.
20. Reiter, R.J., Tan, D.X., Fuentes-Broto, L., 2010. Melatonin: a multitasking molecule. Prog. Brain Res. 181, 127-151.
21. Requena, A., Bronet, F., Guillen, A., Agudo, D., Bou, C., Garcia-Velasco, J.A., 2009. The impact of in-vitro maturation of oocytes on aneuploidy rate. Reprod. Biomed. Online 18, 777-783.
22. Ronnberg, L., Kauppila, A., Leppaluoto, J., Martikainen, H., Vakkuri, O., 1990. Circadian and seasonal variation in human preovulatory follicular fluid melatonin concentration. J. Clin. Endocrinol. Metab. 71, 492-496.
23. Rotterdam ESHRE/ASRM-sponsored PCOS Consensus Workshop Group, 2004. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil. Steril. 81, 19-25.
24. Roy, S.K., Greenwald, G.S., 1987. In vitro steroidogenesis by primary to antral follicles in the hamster during the periovulatory period: effects of follicle-stimulating hormone, luteinizing hormone, and prolactin. Biol. Reprod. 37, 39-46.
25. Shi, J.M., Tian, X.Z., Zhou, G.B., Wang, L., Gao, C., Zhu, S.E., Zeng, S.M., Tian, J.H., Liu, G.S., 2009. Melatonin exists in porcine follicular fluid and improves in vitro maturation and parthenogenetic development of porcine oocytes. J. Pineal Res. 47, 318-323.
26. Tamura, H., Nakamura, Y., Korkmaz, A., Manchester, L.C., Tan, D.X., Sugino, N., Reiter, R.J., 2009. Melatonin and the ovary: physiological and pathophysiological implications. Fertil. Steril. 92, 328-343.
27. Trounson, A., Wood, C., Kausche, A., 1994. In vitro maturation and the fertilization and developmental competence of oocytes recovered from untreated polycystic ovarian patients. Fertil. Steril. 62, 353-362.
28. Vanecek, J., 1995. Melatonin inhibits increase of intracellular calcium and cyclic AMP in neonatal rat pituitary via independent pathways. Mol. Cell. Endocrinol. 107, 149-153.
29. Woo, M.M., Tai, C.J., Kang, S.K., Nathwani, P.S., Pang, S.F., Leung, P.C., 2001. Direct action of melatonin in human granulosa-luteal cells. J. Clin. Endocrinol. Metab. 86, 4789-4797.
30. Yie, S.M., Niles, L.P., Younglai, E.V., 1995. Melatonin receptors on human granulosa cell membranes. J. Clin. Endocrinol. Metab. 80, 1747-1749.