Weakly acidic gastroesophageal refluxes are frequently triggers in young children with chronic cough

Pediatric Pulmonology

Volumn 48, Issue 3, 2013, Pages 295-302

  Ghezzi, Michele ^a   Guida, Edoardo ^a   Ullmann, Nicola ^a   Sacco, Oliviero ^a   Mattioli, Girolamo ^a   Jasonni, Vincenzo ^a   Rossi, Giovanni A ^a   Silvestri, Michela ^a  

^a G GASLINI INSTITUTE   (Italy)

Author keywords

impedance pH recording; infants; preschool children; school aged children

Indexed keywords

ANTACID AGENT;

ARTICLE; ASTHMA; CHILD; CHRONIC COUGH; CLINICAL ASSESSMENT; ESOPHAGOGASTRODUODENOSCOPY; FEMALE; FIBEROPTIC BRONCHOSCOPY; GASTRIC PH MONITORING; GASTROESOPHAGEAL REFLUX; GROUPS BY AGE; HUMAN; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; MULTIDETECTOR COMPUTED TOMOGRAPHY; PRESCHOOL CHILD; PRIORITY JOURNAL; RADIODIAGNOSIS; RECURRENT INFECTION; SCHOOL CHILD; STOMACH ACID; WHEEZING;

CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; COUGH; ESOPHAGEAL PH MONITORING; FEMALE; GASTROESOPHAGEAL REFLUX; HUMANS; HYDROGEN-ION CONCENTRATION; INFANT; MALE; PLETHYSMOGRAPHY, IMPEDANCE; RETROSPECTIVE STUDIES;

EID: 84874111118     PISSN: 87556863     EISSN: 10990496     Source Type: Journal    
DOI: 10.1002/ppul.22581     Document Type: Article

References (30)

1. Massie J,. Cough in children: when does it matter ? Paediatr Respir Rev 2006; 7: 9-14.
2. Morice AH, Fontana GA, Sovijarvi AR, Pistolesi M, Chung KF, Widdicombe J, O'Connell F, Geppetti P, Gronke L, De Jongste J, et al. The diagnosis and management of chronic cough. Eur Respir J 2004; 24: 481-492.
3. Sacco O, Mattioli G, Girosi D, Battistini E, Jasonni V, Rossi GA,. Gastroesophageal reflux and its clinical manifestation at gastroenteric and respiratory levels in childhood: physiology, signs and symptoms, diagnosis and treatment. Expert Rev Respir Med 2007; 1: 391-401.
4. McGarvey LP,. Cough. 6: which investigations are most useful in the diagnosis of chronic cough ? Thorax 2004; 59: 342-346.
5. Chang AB, Lasserson TJ, Gaffney J, Connor FL, Garske LA,. Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults. Cochrane Database Syst Rev 2011; 19: CD004823.
6. Boesch RP, Daines C, Willging JP, Willging JP, Kaul A, Cohen AP, Wood RE, Amin RS,. Advances in the diagnosis and management of chronic pulmonary aspiration in children. Eur Respir J 2006; 28: 847-861.
7. Sacco O, Fregonese B, Silvestri M, Sabatini F, Mattioli G, Rossi GA,. Bronchoalveolar lavage and esophageal pH monitoring data in children with "difficult to treat" respiratory symptoms. Pediatr Pulmonol 2000; 30: 313-319.
8. Bredenoord AJ, Tutuian R, Smout AJ, Castell DO,. Technology review: esophageal impedance monitoring. Am J Gastroenterol 2007; 102: 187-194.
9. Wenzl TG,. Evaluation of gastroesophageal reflux events in children using multichannel intraluminal electrical impedance. Am J Med 2003; 115: 161S-165S.
10. Mattioli G, Pini-Prato A, Gentilino V, Caponcelli E, Avanzini S, Parodi S, Rossi GA, Tuo P, Gandullia P, Vella C, et al. Esophageal impedance/pH monitoring in pediatric patients: preliminary experience with 50 cases. Dig Dis Sci 2006; 51: 2341-2347.
11. Salvatore S, Arrigo S, Luini C, Vandenplas Y,. Esophageal impedance in children: symptom-based results. J Pediatr 2010; 157: 949-954; e1-e2.
12. Rosen R, Lord C, Nurko S,. The sensitivity of multichannel intraluminal impedance and the pH probe in the evaluation of gastroesophageal reflux in children. Clin Gastroenterol Hepatol 2006; 4: 167-172.
13. Thilmany C, Beck-Ripp J, Griese M,. Acid and non-acid gastro-esophageal refluxes in children with chronic pulmonary diseases. Respir Med 2007; 101: 969-976.
14. Blondeau K, Mertens V, Dupont L, Pauwels A, Farré R, Malfroot A, De Wachter E, De Schutter I, Hauser B, Vandenplas Y, et al. The relationship between gastroesophageal reflux and cough in children with chronic unexplained cough using combined impedance-pH-manometry recordings. Pediatr Pulmonol 2011; 46: 286-294.
15. Sifrim D, Castell D, Dent J, Kahrilas PJ,. Gastro-oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux. Gut 2004; 53: 1024-1031.
16. Lam HG, Breumelhof R, Roelofs JM, Van Berge Henegouwen GP, Smout AJ,. What is the optimal time window in symptom analysis of 24-hour esophageal pressure and pH data ? Dig Dis Sci 1994; 39: 402-409.
17. Rosen R, Nurko S,. The importance of multichannel intraluminal impedance in the evaluation of children with persistent respiratory symptoms. Am J Gastroenterol 2004; 99: 2452-2458.
18. Dixon WJ, Massey FJ,. Introduction to statistical analysis, 4th edition. New York: McGraw-Hill; 1983. pp 105-107.
19. Laukka MA, Cameron AJ, Schei AJ,. Gastroesophageal reflux and chronic cough: which comes first ? J Clin Gastroenterol 1994; 19: 100-104.
20. Tolia V, Vandenplas Y,. Systematic review: the extra-oesophageal symptoms of gastro-oesophageal reflux disease in children. Aliment Pharmacol Ther 2009; 29: 258-272.
21. Paterson WG, Murat BW,. Combined ambulatory esophageal manometry and dual-probe pH-metry in evaluation of patients with chronic unexplained cough. Dig Dis Sci 1994; 39: 1117-1125.
22. Francavilla R, Magistà AM, Bucci N, Villirillo A, Boscarelli G, Mappa L, Leone G, Fico S, Castellaneta S, Indrio F, et al. Comparison of esophageal pH and multichannel intraluminal impedance testing in pediatric patients with suspected gastroesophageal reflux. J Pediatr Gastroenterol Nutr 2010; 50: 154-160.
23. Lõpez-Alonso M, Moya MJ, Cabo JA, Ribas J, del Carmen Macías M, Silny J, Sifrim D,. Twenty-four-hour esophageal impedance-pH monitoring in healthy preterm neonates: rate and characteristics of acid, weakly acidic, and weakly alkaline gastroesophageal reflux. Pediatrics 2006; 118: e299-e308.
24. Corvaglia L, Zama D, Gualdi S, Ferlini M, Aceti A, Faldella G,. Gastro-oesophageal reflux increases the number of apnoeas in very preterm infants. Arch Dis Child Fetal Neonatal Ed 2009; 94: F188-F192.
25. Van Wijk MP, Benninga MA, Omari TI,. Role of the multichannel intraluminal impedance technique in infants and children. J Pediatr Gastroenterol Nutr 2009; 48: 2-12.
26. Orenstein SR, Hassall E, Furmaga-Jablonska W, Atkinson S, Raanan M,. Multicenter, double-blind, randomized, placebo-controlled trial assessing the efficacy and safety of proton pump inhibitor lansoprazole in infants with symptoms of gastroesophageal reflux disease. J Pediatr 2009; 154: 514-520.
27. Chang AB, Connor FL, Petsky HL, Eastburn MM, Lewindon PJ, Hall C, Wilson SJ, Katelaris PH,. An objective study of acid reflux and cough in children using an ambulatory pHmetry-cough logger. Arch Dis Child 2011; 96: 468-472.
28. Kaltenback T, Crockett S, Gerson LB,. Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach. Arch Intern Med 2006; 166: 965-971.
29. Ghezzi M, Silvestri M, Guida E, Pistorio A, Sacco O, Mattioli G, Jasonni V, Rossi GA,. Acid and weakly acid gastroesophageal refluxes and type of respiratory symptoms in children. Respir Med 2011; 105: 972-978.
30. Chang AB, Newman RG, Phelan PD, Robertson CF,. A new use for an old Holter monitor: an ambulatory cough meter. Eur Respir J 1997; 10: 1637-1639.