Fertility-sparing treatment of endometrial cancer precursors among young women: A reproductive point of view

European Review for Medical and Pharmacological Sciences

Volumn 16, Issue 14, 2012, Pages 1934-1937

  Ricciardi, E ^a   Maniglio, P ^a   Frega, A ^a   Marci, R ^b   Caserta, D ^a   Moscarini, M ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

Author keywords

Atypical hyperplasia; Endometrial Cancer; Pregnancy; Progestin

Indexed keywords

CA 125 ANTIGEN; CLOMIFENE CITRATE; MEDROXYPROGESTERONE ACETATE; MEGESTROL ACETATE;

ADULT; ARTICLE; CANCER GROWTH; CANCER HORMONE THERAPY; CANCER REGRESSION; CANCER SURGERY; CLINICAL ARTICLE; COMPLEX ATYPICAL HYPERPLASIA; CONSERVATIVE TREATMENT; EARLY CANCER; ENDOMETRIUM BIOPSY; ENDOMETRIUM CANCER; ENDOMETRIUM CARCINOMA; ENDOMETRIUM HYPERPLASIA; FEMALE; FEMALE FERTILITY; FERTILIZATION IN VITRO; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYSTERECTOMY; HYSTEROSCOPY; MULTIMODALITY CANCER THERAPY; MULTIPLE CYCLE TREATMENT; OVULATION INDUCTION; PATIENT COUNSELING; PREGNANCY; PROTEIN BLOOD LEVEL; TREATMENT DURATION; TREATMENT FAILURE; TREATMENT RESPONSE;

ADMINISTRATION, ORAL; ADULT; ANTINEOPLASTIC AGENTS, HORMONAL; BIOPSY; DISEASE PROGRESSION; DRUG ADMINISTRATION SCHEDULE; ENDOMETRIAL HYPERPLASIA; ENDOMETRIAL NEOPLASMS; FEMALE; FERTILITY; FERTILITY PRESERVATION; GYNECOLOGIC SURGICAL PROCEDURES; HUMANS; HYSTEROSCOPY; INFERTILITY, FEMALE; NEOPLASM STAGING; PRECANCEROUS CONDITIONS; PREGNANCY; PREGNANCY RATE; PROGESTINS; REMISSION INDUCTION; TIME FACTORS; TREATMENT OUTCOME;

EID: 84874098707     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. KURMAN RJ, KAMINSKI P F, NORRIS HJ The behavior of endometrial hyperplasia. A long-term study of 'untreated' hyperplasia in 170 patients. Cancer 1985; 56: 403-412.
2. GALLUP DG, STOCK RJ Adenocarcinoma of the endometrium in women 40 years of age or younger. Obstet Gynecol 1984; 64: 417-420.
3. JEYARAJAH AR, GALLAGHER CJ, BLAKE P.R., ORAM DH, DOWSETT M, FISHER C, OLIVER RTD; FOR THE LONDON GYNAECOLOGICAL ONCOLOGY GROUP. Long-term follow-up of gonadotrophin-releasing hormone analog treatment for recurrent endometrial cancer. Gynecologic Oncology 1996; 63: 47-52.
4. SHABANI N, KUHN C, KUNZE S., SCHULZE S, MAYR D, DIAN D., GINGELMAIER A, SCHINDLBECK C, WILLGEROTH F., SOMMER H, JESCHKE U, FRIESE K., MYLONAS I. Prognostic significance of oestrogen receptor alpha (ERalpha) and beta (ERbeta), progesterone receptor A (PR-A) and B (PR-B) in endometrial carcinomas. Eur J Cancer 2007; 43: 2434-2444.
5. RANDALL TC, KURMAN RJ Progestin treatment of atypical hyperplasia and well-differentiated carcinoma of the endometrium in women under age 40. Obstet Gynecol 1997; 90: 434-440.
6. MAZZON I, CORRADO G, MORRICONE D., SCAMBIA G. Reproductive preservation for treatment of stage Ia endometrial cancer in a young woman: hysteroscopic resection. Int J Gynecol Cancer 2005; 15: 974-978.
7. GITSCH G, HANZAL E, JENSEN D., HACKER N F. Endometrial cancer in premenopausal women 45 years and younger. Obstet Gynecol 1995; 85: 504-508.
8. EVANS-METCALF E.R., BROOKS SE, REALE F.R., Baker SP Profile of women 45 years of age and younger with endometrial cancer. Obstet Gynecol 1998; 91: 349-354.
9. Walsh C, Holschneider C, Hoang Y., Tieu K, Karlan B, CASS I. Coexisting ovarian malignancy in young women with endometrial cancer. Obstet Gynecol 2005; 106: 693-699.
10. Signorelli M, Caspani G, Bonazzi C., Chiappa V, Perego P, Mangioni C. Fertility-sparing treatment in young women with endometrial cancer or atypical complex hyperplasia: a prospective single-institution experience of 21 cases. BJOG 2009; 116: 114-118.
11. PILLAY OC, WONG TE FONG LF, CROW JC, BENJAMIN E, MOULD T, ATIOMO W, MENON PA, LEONARD AJ, HARDIMAN P. The association between polycystic ovaries and endometrial cancer. Hum Reprod 2006; 21: 924-929.
12. SCHMELER KM, SOLIMAN PT, SUN C.C., SLOMOVITZ BM, GERSHENSON DM, LU KH Endometrial cancer in young, normal-weight women. Gynecol Oncol 2005 Nov; 99: 388-392.
13. ND, ALBERTS D, CURTIN J. Concurrent endometrial carcinoma in women with a biopsy diagnosis of atypical endometrial hyperplasia: a Gynecologic Oncology Group study. Cancer 2006 Feb 15; 106: 812-819.
14. PENNANT S, MANEK S, KEHOE S. Endometrial atypical hyperplasia and subsequent diagnosis of endometrial cancer: a retrospective audit and literature review. J Obstet Gynaecol 2008; 28: 632-633.