Monosomal karyotypes among 1147 chinese patients with acute myeloid leukemia: Prevalence, features and prognostic impact

Asian Pacific Journal of Cancer Prevention

Volumn 13, Issue 11, 2012, Pages 5421-5426

  Yang, Xiao Fei ^a,b   Sun, Ai Ning ^a   Cai, Cheng Sen ^a   Tian, Xiao Peng ^a   Qian, Jun ^b   Chen, Su Ning ^a   Wu, De Pei ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b AFFILIATED PEOPLE S HOSPITAL OF JIANGSU UNIVERSITY   (China)

Author keywords

Acute myeloid leukemia (aml); Chinese; Monosomal karyotype (mk); Prevalence; Prognosis

Indexed keywords

EID: 84874082942     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2012.13.11.5421     Document Type: Article

References (24)

1. Ahn HK, Jang JH, Kim K, et al (2012). Monosomal karyotype in acute myeloid leukemia predicts adverse treatment outcome and associates with high functional multidrug resistance activity. Am J Hematol, 87, 37-41.
2. Breems DA, Van Putten WLJ, De Greef GE, et al (2008). Monosomal karyotype in acute myeloid leukemia: a better indicator of poor prognosis than a complex karyotype. J Clin Oncol, 26, 4791-7.
3. Byrd JC, Mrozek K, Dodge RK, et al (2002). Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). Blood, 100, 4325-36.
4. Chen B, Zhao WL, Jin J, et al (2005). Clinical and cytogenetic features of 508 Chinese patients with myelodysplastic syndrome and comparison with those in Western countries. Leukemia, 19, 767-75.
5. Cheng Y, Wang Y, Wang H, et al (2009). Cytogenetic pro?le of de novo acute myeloid leukemia: a study based on 1432 patients in a single institution of China. Leukemia, 23, 1801-6.
6. Cornelissen JJ, Breems D, van Putten WL, et al (2012). Comparative analysis of the value of allogeneic hematopoietic stem- cell transplantation in acute myeloid leukemia with monosomal karyotype versus other cytogenetic risk categories. J Clin Oncol, 30, 2140-6.
7. Fang M, Storer B, Estey E, et al (2011). Outcome of patients with acute myeloid leukemia with monosomal karyotype who undergo hematopoietic cell transplantation. Blood, 118, 1490-4.
8. Grimwade D, Hills RK, Moorman AV, et al (2010). Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. Blood, 116, 354-65.
9. Haferlach C, Alpermann T, Schnittger S, et al (2012). Prognostic value of "monosomal karyotype" in comparison to "complex aberrant karyotype" in acute myeloid leukemia: study on 824 cases with aberrant karyotype. Blood, 119, 2122-5.
10. Johansson B, Mertens F, Mitelman F (1991). Geographic heterogeneity of neoplasia-associated chromosome aberrations. Genes Chromosomes Cancer, 3, 1-7.
11. Kayser S, Zucknick M, Döhner K, et al (2012). Monosomal karyotype in adult acute myeloid leukemia: prognostic impact and outcome after different treatment strategies. Blood, 119, 551-8.
12. Lowenberg B, Pabst T, Vellenga E, et al (2011). Cytarabine dose for acute myeloid leukemia. N Engl J Med, 364, 1027-36.
13. Medelros BC, Othus M, Appelbaum FR (2011). Cytarabine dose for acute myeloid leukemia. N Engl J Med, 364, 2167-8; author reply 2168-9.
14. Medeiros BC, Othus M, Fang M, et al (2010). Prognostic impact of monosomal karyotype in young adult and elderly acute myeloid leukemia: the Southwest Oncology Group (SWOG) experience. Blood, 116, 2224-8.
15. Mrozek K, Heerema NA, Bloomfeld CD (2004). Cytogenetics in acute leukemia. Blood Rev, 18, 115-36.
16. Nakase K, Bradstock K, Sartor M, et al (2000). Geographic heterogeneity of cellular characteristics of acute myeloid leukemia: a comparative study of Australian and Japanese adult cases. Leukemia, 14, 163-8.
17. Oran B, Dolan M, Cao Q, et al (2011). Monosomal Karyotype Provides Better Prognostic Prediction after Allogeneic Stem Cell Transplantation in AML Patients. Biol Blood Marrow Transplant, 17, 356-64.
18. Patnaik MM, Hanson CA, Hodnefield JM, et al (2011). Monosomal karyotype in myelodysplastic syndromes, with or without monosomy 7 or 5 , is prognostically worse than another wise complex karyotype. Leukemia, 25, 266-70.
19. Perrot A, Luquet I, Pigneux A, et al (2011). Dismal prognostic value of monosomal karyotype in elderly patients with acute myeloid leukemia: a GOELAMS study of 186 patients with unfavorable cytogenetic abnormalities. Blood, 118, 679-85.
20. Rücker FG, Schlenk RF, Bullinger L, et al (2012). TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome. Blood, 119, 2114-21.
21. Sanderson RN, Johnson PRE, Moorman AV, et al (2006). Population-based demographic study of karyotypes in 1709 patients with adult acute myeloid leukemia. Leukemia, 20, 444-50.
22. Slovak ML, Kopecky KJ, Cassileth PA, et al (2000). Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study. Blood, 96, 4075-83.
23. Vaidya R, Caramazza D, Begna KH, et al (2011). Monosomal karyotype in primary myelofibrosis is detrimental to both overall and leukemia-free survival. Blood, 117, 5612-15.
24. Yanada M, Kurosawa S, Yamaguchi T, et al (2012). Prognosis of acute myeloid leukemia harboring monosomal karyotype in patients treated with or without allogeneic hematopoietic cell transplantation after achieving complete remission. Haematologica, 97, 915-8.