Green Chemistry Metrics

Green Chemistry in the Pharmaceutical Industry

Volumn , Issue , 2010, Pages 21-48

  Henderson, Richard K ^a   Constable, David J C ^b   Jiménez González, Concepción ^c  

^a GLAXOSMITHKLINE   (United Kingdom)

^b GlaxoSmithKline Pharmaceuticals ^*  (United States)

^c GLAXOSMITHKLINE   (United States)

Author keywords

Controllability; Green chemistry metrics; Hazard ranking; Inherent safety; Life cycle analysis; Renewables; Robustness; Scalability; Solvents; Twelve principles

Indexed keywords

CHEMICAL ANALYSIS; CONTROLLABILITY; ROBUSTNESS (CONTROL SYSTEMS); SCALABILITY; SOLVENTS;

GREEN CHEMISTRY; HAZARD RANKING; INHERENT SAFETY; LIFE CYCLE ANALYSIS; RENEWABLES; TWELVE PRINCIPLES;

LIFE CYCLE;

EID: 84874079060     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527629688.ch2     Document Type: Chapter

References (60)

1. Anastas, P.T., and Warner, J.C. (1998) Green Chemistry: Theory and Practice, Oxford University Press, Oxford, UK.
2. Constable, D.J.C., Curzons, A.D., dos Santos, L.M.F., Geen, G.R., Hannah, R.E., Hayler, J.D., Kitteringham, J., McGuire, M.A., Richardson, J.E., Smith, P., Webb, R.L., and Yu, M. (2001) Green Chem., 3, 7-9.
3. CWRT (2000) Baseline metric and other documents posted on the website of the Centre for Waste Reduction Technologies, http://www.aiche.org/cwrt/ (last accessed 22 October 2008) http://198.6.4.175/cwrt/ (last accessed 22 October 2008) http://www.aiche.org/uploaded-Files/IFS/Products/TCAM. pdf (last accessed 22 October 2008) http://www.aiche. org/uploadedFiles/IFS/Forum/Uploads/Automating_Sustainability_Metrics.pdf (last accessed 22 October 2008).
4. IChemE (2003) The Sustainability Metrics, The Institution of Chemical Engineers, Rugby, UK. http://www.icheme.org/sustainability/metrics.pdf (last accessed 22 October 2008).
5. Curzons, A.D., Constable, D.J.C., Mortimer, D.N., and Cunningham, V.L. (2001) Green Chem., 3, 1-6.
6. Constable, D.J.C., Curzons, A.D., and Cunningham, V.L. (2002) Green Chem., 4, 521-527.
7. Jiménez-González, C., Curzons, A.D., Constable, D.J.C., Overcash, M.R., and Cunningham, V.L. (2001) Clean Prod. Process, 3, 35-41.
8. Jiménez-González, C., Constable, D.J.C., Curzons, A.D., and Cunningham, V.L. (2002) Clean Technol. Environ. Policy, 4, 44-53.
9. Jiménez-González, C., Curzons, A.D., Constable, D.J.C., and Cunningham, V.L. (2004) Int.J. LCA, 9 (2), 114-121.
10. Butters, M., Catterick, D., Craig, A., Curzons, A.D., Dale, D., Gillmore, A., Green, S.P., Marziano, I., Sherlock, J.-P., and White, W. (2006) Chem. Rev., 106 (7), 3002-3027.
11. Marteel, A.E., Davies, J.A., Olson, W.W., and Abraham, M.A. (2003) Annu. Rev. Environ. Resour., 28, 401-428.
12. Wrisberg, N., de Haes, H.A.U., Bilitewski, B., Bringezu, S., Bro-Rasmussen, F., Clift, R., Eder, P., Ekins, P., Frischknecht, R., and Triebswetter, U. (2002) Analytical Toolsfor Environmental Design and Management in a Systems Perspective (eds N. Wrisberg, H.A.U. de Haes, U. Triebswetter, P. Eder, and R. Clift), Kluwer Academic Publishers (Springer), Dordrecht, The Netherlands, pp. 45-73.
13. Lapkin, A. (2006) Renewables-Based Technology: Sustainability Assessment (eds J. Dewulf, I.H.V. Langenhove), John Wiley & Sons, Ltd, Chichester, UK, pp. 39-53.
14. Brunner, N., and Starkl, M. (2004) Environ. Impact Assess. Rev., 24, 441-469.
15. Heaton, C.A. (1995) An Introduction to Industrial Chemistry, 3rd edn, Blackie Academic and Professional (Springer), London, UK.
16. Carson, R. (1962) Silent Spring, Hamish Hamilton, London, UK.
17. Porteous, A. (1992) Dictionary of Environmental Science and Technology, John Wiley & Sons, Ltd, Chichester, UK.
18. Dale, B. (2003) Managing Quality, 4th edn, John Wiley & Sons, Ltd, Oxford, UK.
19. Sheldon, R.A. (1992) Chem. Ind. (London), 23, 903-906
20. Sheldon, R.A. (2007) Green Chem., 9, 1273-1283.
21. Sheldon, R.A. (1994) Chemtech, 24, 38-47.
22. ACS Green Chemistry Institute Pharmaceutical Roundtable(2007) Lessons learned through measuring green chemistry performance-the pharmaceutical experience, presentation on website http://portal. acs. org/portal/fileFetch/C/CTP_005585/pdf/CTP_005585. pdf (last accessed 16 October 2008).
23. Sheldon, R.A. (1997) J. Chem. Technol. Biotechnol., 68, 381-388.
24. Thomas, M. (2008) Belching Out the Devil: Global Adventures with Coca-Cola, Ebury Press, England.
25. Constable, D.J.C., Jiménez-González, C., and Henderson, R.K. (2007) Org. Process Res. Dev., 11, 133-137.
26. Tucker, J.L. (2006) Org. Process Res. Dev., 10 (2), 315-319.
27. Curzons, A.D., Constable, D.J.C., and Cunningham, V.L. (1999) Clean Prod. Process, 1, 82-90.
28. Jiménez-González, C., Curzons, A.D., Constable, D.J.C., and Cunningham, V.L. (2005) J. Clean Technol. Environ. Policy, 7, 42-50.
29. Alfonsi, K., Colberg, J., Dunn, P.J., Fevig, T., Jennings, S., Johnson, T.A., Kleine, H.P., Knight, C., Nagy, M.A., Perry, D.A. and Stefaniak, M. (2008) Green Chem., 1, 31-36.
30. ACS GCI Pharmaceutical Roundtable (2008) Collaboration to deliver a solvent selection guide for the pharmaceutical industry. Presentation at the AIChE Annual Conference, http://aiche.confex. com/aiche/2008/techprogram/P125149. HTM (last accessed 22 October 2008).
31. Kim, S., and Dale, B. (2005) Int. J. LCA, 10 (2), 200-210.
32. Kim, S., and Dale, B. (2006) Int. J. LCA, 11 (2), 117-121.
33. Kløverpris, J.H., Wenzel, H., and Nielsen, P.H. (2008) Int.J. LCA, 13 (1), 13-21.
34. Henderson, R.K., Jiménez-González, C., Preston, C., Constable, D.J.C., and Woodley, J.M. (2008) Ind. Biotechnol, 4 (2), 180-192.
35. Jiménez-González, C., and Constable, D.J.C. (2008) Green Chemistry Metrics, Chapter 7 (eds A. Lapkin and D.J.C. Constable), John Wiley & Sons, Ltd, Chichester, UK.
36. Jiménez-González, C. (2000) Life Cycle Assessment in Pharmaceutical Applications, Ph.D. Thesis, North Carolina State University, Raleigh NC.
37. CALCAS (2006) Coordination Action for innovation in Life Cycle Analysis for Sustainability, a pan-European project, financed by the Sixth Framework Programme of the European Commission. http://www.calcasproject.net/ (last accessed 22 October 2008).
38. ACLCA (2001) American Center for Life Cycle Assessment, http://lcacenter.org/index.html (last accessed 7 December 2008).
39. Azapagic, A. (2007) Carbon Calculations over the Life Cycle of Industrial Activities (CCaLC), a project to develop a life cycle methodology and decisionsupport tools for calculation and reduction of carbon footprints of different industrial sectors along complete supply chains. http://innovation. globalwatchonline. com/epicentric_portal/site/Innovation/menuitem. 8e9f93a252aab8e-962c40a108680e1a0/(last accessed 22 October 2008).
40. UNEP (2001) The Life Cycle Initiative, http://lcinitiative.unep.fr/ (last accessed 7 December 2008).
41. Jödicke, G., Zenklusen, O., Weidenhaupt, A., and Hungerbühler, K. (1999) J. Clean. Prod., 7, 159-166.
42. Conradt, S. (2008) Life Cycle Assessment of a Pharmaceutical Compound, M.Sc. Thesis, ETH-Zürich.
43. Curzons, A.D., Jiménez-González, C., Duncan, A.L., Constable, D.J.C. and Cunningham, V.L. (2007) Int.J. LCA, 12 (4), 272-280.
44. Trost, B.M. (1991) Science, 254, 1471-1477.
45. Trost, B.M. (1995) Angew. Chem. Int. Ed., 34, 259-281.
46. Li, C.-J., and Trost, B.M. (2008) Proc. Natl. Acad. Sci. U. S. A., 105, 13197-13202.
47. GlaxoSmithKline (2003) Green Chemistry Guide, GlaxoSmithKline.
48. Slack, N., Chambers, S., and Johnson, R. (2001) Operations Management, 3rd edn, Chapter 11, FT Prentice Hall, UK.
49. Anallou, R. (1993-2008) European Chemical Substance Information System (ESIS), Euroean Chemicals Bureau, http://ecb.jrc.ec.europa.eu/esis/ (last accessed 22 October 2008).
50. AIChE (1998) Dow's Chemical Exposure Index Guide, 1st edn, AIChE, USA.
51. 0EÚ Council Directive 67/548/EEC (1967) and its subsequent amendments, http://ecb. jrc. ec. europa. eu/esis/index. php?PGM=cla (last accessed 22 October 2008).
52. Touraud, E., and Roig, B. (2008) KNAPPE (Knowledge and Need Assessment on Pharmaceutical Products in Environmental Waters) http://www.knappe-eu.org/fichiers/60-D6.6%20 final%20report%20final.pdf (last accessed 4 January 2010).
53. MacKay, D., Shiu, W.Y., Ma, K., and Lee, S.C. (2006) Handbook ofPhysical-Chemical Properties and Environmental Fate for Organic Chemicals, 2nd edn, CRC Press, Florida, USA.
54. Cronin, M., and Livingstone, D. (eds) (2004) Predicting Chemical Toxicity and Fate, CRC Press, Florida, USA.
55. OECD (2001) Guidelinesfor the Testing of Chemicals, 13th Addendum, OECD Publishing, Paris, France.
56. Hurme, M., Rahman, M., and Loss, J. (2005) Prev. Process Ind., 18 (4-6), 238-244.
57. AIChE (1994) Dow's Fire & Explosion Index Hazard Classification Guide, 7th edn, AIChE, USA.
58. Stoessel, F. (1993) Chem. Eng. Prog., 89 (10), 68-75.
59. Edwards, D.W., and Lawrence, D. (1993) Trans. Inst. Chem. Eng., 71, Part B, 252-258.
60. Heikkilä, A.-M., Hurme, M., and Järveläinen, M. (1996) Comput. Chem. Eng, 20, S115-S120.