Vitamin B-6 restriction impairs fatty acid synthesis in cultured human hepatoma (HepG2) cells

American Journal of Physiology - Endocrinology and Metabolism

Volumn 304, Issue 4, 2013, Pages

  Zhao, Mei ^a   Ralat, Maria A ^a   da Silva, Vanessa ^a   Garrett, Timothy J ^b   Melnyk, Stephan ^c   Jill James, S ^c   Gregory III, Jesse F ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Fatty acid profiles; Human hepatoma cells; Stable isotopes

Indexed keywords

ACYL COENZYME A DESATURASE 1; ARACHIDONIC ACID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LINOLEOYL COENZYME A DESATURASE; MESSENGER RNA; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PYRIDOXAL 5 PHOSPHATE;

ARTICLE; CELL LEVEL; CELL STRAIN HEPG2; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; FATTY ACID SYNTHESIS; HUMAN; HUMAN CELL; LIPID COMPOSITION; LIVER CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRIDOXINE DEFICIENCY; STEADY STATE;

CARCINOMA, HEPATOCELLULAR; CELL MEMBRANE; DOWN-REGULATION; FATTY ACID DESATURASES; FATTY ACIDS; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; HEP G2 CELLS; HEPATOCYTES; HUMANS; INTRACELLULAR MEMBRANES; KINETICS; LINOLEOYL-COA DESATURASE; LIVER NEOPLASMS; NEOPLASM PROTEINS; OSMOLAR CONCENTRATION; PYRIDOXAL; PYRIDOXAL PHOSPHATE; RNA, MESSENGER; VITAMIN B 6 DEFICIENCY;

EID: 84874073870     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00359.2012     Document Type: Article

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