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Volumn 8, Issue 3, 2013, Pages 346-351

Local therapy with continued EGFR tyrosine kinase inhibitor therapy as a treatment strategy in EGFR-mutant advanced lung cancers that have developed acquired resistance to EGFR tyrosine kinase inhibitors

Author keywords

Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors; EGFR mutant lung cancer; Local therapy; Metastasectomy

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR;

EID: 84874065941     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e31827e1f83     Document Type: Article
Times cited : (295)

References (42)
  • 1
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004;101: 13306-13311.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 2
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007;448: 561-566.
    • (2007) Nature , vol.448 , pp. 561-566
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3
  • 3
    • 36849065315 scopus 로고    scopus 로고
    • Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
    • Rikova K, Guo A, Zeng Q, et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007;131: 1190-1203.
    • (2007) Cell , vol.131 , pp. 1190-1203
    • Rikova, K.1    Guo, A.2    Zeng, Q.3
  • 4
    • 84857929267 scopus 로고    scopus 로고
    • KIF5B-RET fusions in lung adenocarcinoma
    • Kohno T, Ichikawa H, Totoki Y, et al. KIF5B-RET fusions in lung adenocarcinoma. Nat Med 2012;18: 375-377.
    • (2012) Nat Med , vol.18 , pp. 375-377
    • Kohno, T.1    Ichikawa, H.2    Totoki, Y.3
  • 5
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350: 2129-2139.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 6
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Jänne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304: 1497-1500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Jänne, P.A.2    Lee, J.C.3
  • 7
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361: 947-957.
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 8
    • 75249087060 scopus 로고    scopus 로고
    • Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (wjtog3405): An open label randomised phase 3 trial
    • West Japan Oncology Group
    • Mitsudomi T, Morita S, Yatabe Y, et al.; West Japan Oncology Group. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2010;11: 121-128.
    • (2010) Lancet Oncol , vol.11 , pp. 121-128
    • Mitsudomi, T.1    Morita, S.2    Yatabe, Y.3
  • 9
    • 77953930730 scopus 로고    scopus 로고
    • Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
    • North-East Japan Study Group
    • Maemondo M, Inoue A, Kobayashi K, et al.; North-East Japan Study Group. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010;362: 2380-2388.
    • (2010) N Engl J Med , vol.362 , pp. 2380-2388
    • Maemondo, M.1    Inoue, A.2    Kobayashi, K.3
  • 10
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for european patients with advanced egfr mutation-positive non-small-cell lung cancer (eurtac): A multicentre open-label randomised phase 3 trial
    • Spanish Lung Cancer Group In Collaboration With Groupe Français De Pneumo-Cancérologie And Associazione Italiana Oncologia Toracica
    • Rosell R, Carcereny E, Gervais R, et al.; Spanish Lung Cancer Group in collaboration with Groupe Français de Pneumo-Cancérologie and Associazione Italiana Oncologia Toracica. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012;13: 239-246.
    • (2012) Lancet Oncol , vol.13 , pp. 239-246
    • Rosell, R.1    Carcereny, E.2    Gervais, R.3
  • 11
    • 84862819699 scopus 로고    scopus 로고
    • Afatinib for patients with lung adenocarcinoma and epidermal growth factor receptor mutations (LUX-Lung 2): A phase 2 trial
    • Yang JC, Shih JY, Su WC, et al. Afatinib for patients with lung adenocarcinoma and epidermal growth factor receptor mutations (LUX-Lung 2): a phase 2 trial. Lancet Oncol 2012;13: 539-548.
    • (2012) Lancet Oncol , vol.13 , pp. 539-548
    • Yang, J.C.1    Shih, J.Y.2    Su, W.C.3
  • 12
    • 84863892117 scopus 로고    scopus 로고
    • Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB 30406 trial
    • Jänne PA, Wang X, Socinski MA, et al. Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB 30406 trial. J Clin Oncol 2012;30: 2063-2069.
    • (2012) J Clin Oncol , vol.30 , pp. 2063-2069
    • Jänne, P.A.1    Wang, X.2    Socinski, M.A.3
  • 13
    • 79953118839 scopus 로고    scopus 로고
    • Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
    • Sequist LV, Waltman BA, Dias-Santagata D, et al. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med 2011;3: 75ra26.
    • (2011) Sci Transl Med , vol.3
    • Sequist, L.V.1    Waltman, B.A.2    Dias-Santagata, D.3
  • 14
    • 13844317894 scopus 로고    scopus 로고
    • EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
    • Kobayashi S, Boggon TJ, Dayaram T, et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 2005;352: 786-792.
    • (2005) N Engl J Med , vol.352 , pp. 786-792
    • Kobayashi, S.1    Boggon, T.J.2    Dayaram, T.3
  • 15
    • 34249075147 scopus 로고    scopus 로고
    • MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
    • Engelman JA, Zejnullahu K, Mitsudomi T, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 2007;316: 1039-1043.
    • (2007) Science , vol.316 , pp. 1039-1043
    • Engelman, J.A.1    Zejnullahu, K.2    Mitsudomi, T.3
  • 16
    • 38049150665 scopus 로고    scopus 로고
    • MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
    • Bean J, Brennan C, Shih JY, et al. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci USA 2007;104: 20932-20937.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20932-20937
    • Bean, J.1    Brennan, C.2    Shih, J.Y.3
  • 17
    • 33745913034 scopus 로고    scopus 로고
    • Memorial sloan-kettering cancer center lung cancer oncogenome group. egfr mutations in small-cell lung cancers in patients who have never smoked
    • Zakowski MF, Ladanyi M, Kris MG; Memorial Sloan-Kettering Cancer Center Lung Cancer OncoGenome Group. EGFR mutations in small-cell lung cancers in patients who have never smoked. N Engl J Med 2006;355: 213-215.
    • (2006) N Engl J Med , vol.355 , pp. 213-215
    • Zakowski, M.F.1    Ladanyi, M.2    Kris, M.G.3
  • 18
    • 79960085862 scopus 로고    scopus 로고
    • Optimization of dosing for EGFRmutant non-small cell lung cancer with evolutionary cancer modeling
    • Chmielecki J, Foo J, Oxnard GR, et al. Optimization of dosing for EGFRmutant non-small cell lung cancer with evolutionary cancer modeling. Sci Transl Med 2011;3: 90ra59.
    • (2011) Sci Transl Med , vol.3
    • Chmielecki, J.1    Foo, J.2    Oxnard, G.R.3
  • 19
    • 80053531654 scopus 로고    scopus 로고
    • Disease flare after tyrosine kinase inhibitor discontinuation in patients with EGFR-mutant lung cancer and acquired resistance to erlotinib or gefitinib: Implications for clinical trial design
    • Chaft JE, Oxnard GR, Sima CS, Kris MG, Miller VA, Riely GJ. Disease flare after tyrosine kinase inhibitor discontinuation in patients with EGFR-mutant lung cancer and acquired resistance to erlotinib or gefitinib: implications for clinical trial design. Clin Cancer Res 2011;17: 6298-6303.
    • (2011) Clin Cancer Res , vol.17 , pp. 6298-6303
    • Chaft, J.E.1    Oxnard, G.R.2    Sima, C.S.3    Kris, M.G.4    Miller, V.A.5    Riely, G.J.6
  • 20
    • 84867066459 scopus 로고    scopus 로고
    • Chemotherapy with erlotinib or chemotherapy alone in advanced NSCLC with acquired resistance to EGFR tyrosine kinase inhibitors (TKI)
    • (suppl; abstr 7524)
    • Goldberg SB, Oxnard GE, Digumarthy S, et al. Chemotherapy with erlotinib or chemotherapy alone in advanced NSCLC with acquired resistance to EGFR tyrosine kinase inhibitors (TKI). J Clin Oncol 2012: 30 (suppl; abstr 7524).
    • (2012) J Clin Oncol , vol.30
    • Goldberg, S.B.1    Oxnard, G.E.2    Digumarthy, S.3
  • 21
    • 33646564999 scopus 로고    scopus 로고
    • Surgery for colorectal and sarcomatous pulmonary metastases: History, current management, and future directions
    • v
    • Downey RJ. Surgery for colorectal and sarcomatous pulmonary metastases: history, current management, and future directions. Thorac Surg Clin 2006;16: 133-7, v.
    • (2006) Thorac Surg Clin , vol.16 , pp. 133-137
    • Downey, R.J.1
  • 22
    • 55249093686 scopus 로고    scopus 로고
    • Surgical intervention in patients with metastatic renal cancer: Metastasectomy and cytoreductive nephrectomy
    • viii
    • Russo P, O'Brien MF. Surgical intervention in patients with metastatic renal cancer: metastasectomy and cytoreductive nephrectomy. Urol Clin North Am 2008;35: 679-86; viii.
    • (2008) Urol Clin North Am , vol.35 , pp. 679-686
    • Russo, P.1    O'Brien, M.F.2
  • 26
    • 77953152570 scopus 로고    scopus 로고
    • Reported outcome factors for pulmonary resection in metastatic colorectal cancer
    • Pfannschmidt J, Hoffmann H, Dienemann H. Reported outcome factors for pulmonary resection in metastatic colorectal cancer. J Thorac Oncol 2010;5(6 Suppl 2):S172-S178.
    • (2010) J Thorac Oncol , vol.5 , Issue.6 SUPPL. 2
    • Pfannschmidt, J.1    Hoffmann, H.2    Dienemann, H.3
  • 27
    • 33846163121 scopus 로고    scopus 로고
    • Factors causing early relapse after lung metastasis surgery
    • Ríos A, Galindo PJ, Torres J, et al. Factors causing early relapse after lung metastasis surgery. Eur J Cancer Care (Engl) 2007;16: 26-32.
    • (2007) Eur J Cancer Care (Engl) , vol.16 , pp. 26-32
    • Ríos, A.1    Galindo, P.J.2    Torres, J.3
  • 28
    • 84856958788 scopus 로고    scopus 로고
    • Pulmonary metastasectomy: A multivariate analysis of 440 patients undergoing complete resection
    • Younes RN, Fares AL, Gross JL. Pulmonary metastasectomy: a multivariate analysis of 440 patients undergoing complete resection. Interact Cardiovasc Thorac Surg 2012;14: 156-161.
    • (2012) Interact Cardiovasc Thorac Surg , vol.14 , pp. 156-161
    • Younes, R.N.1    Fares, A.L.2    Gross, J.L.3
  • 29
    • 80051802370 scopus 로고    scopus 로고
    • A 10-year single-center experience on 708 lung metastasectomies: The evidence of the "international registry of lung metastases"
    • Casiraghi M, De Pas T, Maisonneuve P, et al. A 10-year single-center experience on 708 lung metastasectomies: the evidence of the "international registry of lung metastases". J Thorac Oncol 2011;6: 1373-1378.
    • (2011) J Thorac Oncol , vol.6 , pp. 1373-1378
    • Casiraghi, M.1    De Pas, T.2    Maisonneuve, P.3
  • 30
  • 31
    • 11144251206 scopus 로고    scopus 로고
    • Lung cancer and its operable brain metastasis: Survival rate and staging problems
    • discussion 241
    • Furák J, Troján I, Szöke T, et al. Lung cancer and its operable brain metastasis: survival rate and staging problems. Ann Thorac Surg 2005;79: 241-7; discussion 241.
    • (2005) Ann Thorac Surg , vol.79 , pp. 241-247
    • Furák, J.1    Troján, I.2    Szöke, T.3
  • 32
    • 77951294288 scopus 로고    scopus 로고
    • Surgical treatment of synchronous multiple lung cancer located in a different lobe or lung: High survival in node-negative subgroup
    • Voltolini L, Rapicetta C, Luzzi L, et al. Surgical treatment of synchronous multiple lung cancer located in a different lobe or lung: high survival in node-negative subgroup. Eur J Cardiothorac Surg 2010;37: 1198-1204.
    • (2010) Eur J Cardiothorac Surg , vol.37 , pp. 1198-1204
    • Voltolini, L.1    Rapicetta, C.2    Luzzi, L.3
  • 33
    • 78649671323 scopus 로고    scopus 로고
    • Prognostic impact of local treatment against postoperative oligometastases in non-small cell lung cancer
    • Yano T, Haro A, Yoshida T, et al. Prognostic impact of local treatment against postoperative oligometastases in non-small cell lung cancer. J Surg Oncol 2010;102: 852-855.
    • (2010) J Surg Oncol , vol.102 , pp. 852-855
    • Yano, T.1    Haro, A.2    Yoshida, T.3
  • 34
    • 0036838163 scopus 로고    scopus 로고
    • A phase II trial of chemotherapy and surgery for non-small cell lung cancer patients with a synchronous solitary metastasis
    • Downey RJ, Ng KK, Kris MG, et al. A phase II trial of chemotherapy and surgery for non-small cell lung cancer patients with a synchronous solitary metastasis. Lung Cancer 2002;38: 193-197.
    • (2002) Lung Cancer , vol.38 , pp. 193-197
    • Downey, R.J.1    Ng, K.K.2    Kris, M.G.3
  • 35
    • 84866751861 scopus 로고    scopus 로고
    • Delay of chemotherapy through use of post-progression erlotinib in patients with EGFR-mutant lung cancer
    • (suppl; abstr 7547)
    • Oxnard GR, Lo P, Jackman DM, et al. Delay of chemotherapy through use of post-progression erlotinib in patients with EGFR-mutant lung cancer. J Clin Oncol 2012: 30 (suppl; abstr 7547).
    • (2012) J Clin Oncol , vol.30
    • Oxnard, G.R.1    Lo, P.2    Jackman, D.M.3
  • 36
    • 84874084209 scopus 로고    scopus 로고
    • Treatment with EGFR tyrosine kinase inhibitors beyond progression in long-term responders to erlotinib in advanced non-small cell lung cancer: A case-control study of overall survival
    • (suppl; abstr 7572)
    • Faehling M, Eckert R, Kamp TG, et al. Treatment with EGFR tyrosine kinase inhibitors beyond progression in long-term responders to erlotinib in advanced non-small cell lung cancer: A case-control study of overall survival. J Clin Oncol 2012: 30 (suppl; abstr 7572).
    • (2012) J Clin Oncol , vol.30
    • Faehling, M.1    Eckert, R.2    Kamp, T.G.3
  • 37
    • 40049100818 scopus 로고    scopus 로고
    • Prognostic and therapeutic implications of EGFR and KRAS mutations in resected lung adenocarcinoma
    • Marks JL, Broderick S, Zhou Q, et al. Prognostic and therapeutic implications of EGFR and KRAS mutations in resected lung adenocarcinoma. J Thorac Oncol 2008;3: 111-116.
    • (2008) J Thorac Oncol , vol.3 , pp. 111-116
    • Marks, J.L.1    Broderick, S.2    Zhou, Q.3
  • 38
    • 79952711946 scopus 로고    scopus 로고
    • Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: Distinct natural history of patients with tumors harboring the T790M mutation
    • Oxnard GR, Arcila ME, Sima CS, et al. Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: distinct natural history of patients with tumors harboring the T790M mutation. Clin Cancer Res 2011;17: 1616-1622.
    • (2011) Clin Cancer Res , vol.17 , pp. 1616-1622
    • Oxnard, G.R.1    Arcila, M.E.2    Sima, C.S.3
  • 39
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006;355: 2542-2550.
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3
  • 40
    • 3042727071 scopus 로고    scopus 로고
    • Preoperative PSA velocity and the risk of death from prostate cancer after radical prostatectomy
    • D'Amico AV, Chen MH, Roehl KA, Catalona WJ. Preoperative PSA velocity and the risk of death from prostate cancer after radical prostatectomy. N Engl J Med 2004;351: 125-135.
    • (2004) N Engl J Med , vol.351 , pp. 125-135
    • D'Amico, A.V.1    Chen, M.H.2    Roehl, K.A.3    Catalona, W.J.4
  • 41
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • Gerlinger M, Rowan AJ, Horswell S, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012;366: 883-892.
    • (2012) N Engl J Med , vol.366 , pp. 883-892
    • Gerlinger, M.1    Rowan, A.J.2    Horswell, S.3
  • 42
    • 85206959537 scopus 로고    scopus 로고
    • Concordance of driver mutations in primary and matched metastasis from patients with non-small cell lung cancer (NSCLC) using next-generation sequencing (NGS)
    • (suppl; abstr 7529)
    • Vignot S, Frampton G, Yelensky R, et al. Concordance of driver mutations in primary and matched metastasis from patients with non-small cell lung cancer (NSCLC) using next-generation sequencing (NGS). J Clin Oncol 2012: 30 (suppl; abstr 7529).
    • (2012) J Clin Oncol , vol.30
    • Vignot, S.1    Frampton, G.2    Yelensky, R.3


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