Synthesis and evaluation of methylated arylazepine compounds for PET imaging of 5-HT2c receptors

ACS Chemical Neuroscience

Volumn 4, Issue 2, 2013, Pages 261-265

  Granda, Michael L ^a   Carlin, Stephen M ^a   Moseley, Christian K ^a   Neelamegam, Ramesh ^a   Mandeville, Joseph B ^a   Hooker, Jacob M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

5 HT2c agonist; carbon 11; PET imaging; Serotonin

Indexed keywords

ALTANSERIN; KETANSERIN; RITANSERIN; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2B RECEPTOR; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; TRACER;

ANIMAL EXPERIMENT; ARTICLE; BABOON; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG METABOLISM; DRUG PENETRATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; DRUG UPTAKE; INTESTINE; KIDNEY; LIVER; MALE; METHYLATION; MOUSE; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

ANIMALS; AZEPINES; BRAIN; CARBON RADIOISOTOPES; METHYLATION; PAPIO ANUBIS; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTOR, SEROTONIN, 5-HT2C; SEROTONIN 5-HT2 RECEPTOR AGONISTS;

EID: 84874059598     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn300223d     Document Type: Article

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