Regio-and enantioselective synthesis of pyrrolidines bearing a quaternary center by palladium-catalyzed asymmetric [3 + 2] cycloaddition of trimethylenemethanes

Journal of the American Chemical Society

Volumn 135, Issue 7, 2013, Pages 2459-2461

  Trost, Barry M ^a   Lam, Tom M ^a   Herbage, Melissa A ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1-FORMS; CHIRAL BUILDING BLOCKS; ENANTIOSELECTIVE SYNTHESIS; PALLADIUM-CATALYZED; PYRROLIDINES; QUATERNARY CENTERS; TRIMETHYLENEMETHANE;

CATALYSIS;

ENANTIOSELECTIVITY;

CARBON; IMINE; METHANE; PALLADIUM; PYRROLIDINE DERIVATIVE; TRIMETHYLENEMETHANE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; COVALENT BOND; CYCLOADDITION; ELECTRON; ENANTIOSELECTIVITY; ISOMERIZATION; SUBSTITUTION REACTION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

EID: 84874032180     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja312351s     Document Type: Article

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