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Volumn 11, Issue 16, 2009, Pages 3782-3785

Access to a welwitindolinone core using sequential cycloadditions

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; DRUG DERIVATIVE; INDOLE DERIVATIVE; NITRILE; OXINDOLE; PALLADIUM; TROPOLONE; TROPONE; WELWITINDOLINONE A;

EID: 68949105302     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol901499b     Document Type: Article
Times cited : (101)

References (29)
  • 12
    • 27644566322 scopus 로고    scopus 로고
    • Two total syntheses of the biosynthetically related welwitindolinone A isonitrile have been reported: (a) Baran, P. S, Richter, J. M. J. Am. Chem. Soc. 2005, 127, 15394-15396
    • Two total syntheses of the biosynthetically related welwitindolinone A isonitrile have been reported: (a) Baran, P. S.; Richter, J. M. J. Am. Chem. Soc. 2005, 127, 15394-15396.
  • 16
    • 65549163567 scopus 로고    scopus 로고
    • Recent progress: (c) Boissel, V.; Simpkins, N. S.; Bhalay, G. Tetrahedron Lett. 2009, 50, 3283-3286.
    • Recent progress: (c) Boissel, V.; Simpkins, N. S.; Bhalay, G. Tetrahedron Lett. 2009, 50, 3283-3286.
  • 24
    • 68949123584 scopus 로고    scopus 로고
    • See the Supporting Information for details
    • See the Supporting Information for details.
  • 26
    • 68949120201 scopus 로고    scopus 로고
    • A commercially available phosphoramidite Aldrich Chemical Co, Inc, Catalog no, See the Supporting Information
    • A commercially available phosphoramidite (Aldrich Chemical Co., Inc., Catalog no. 665290) could also be used, although it gave low ee. See the Supporting Information.
    • 665290) could also be used, although it gave low ee
  • 27
    • 68949087418 scopus 로고    scopus 로고
    • Due to the unstable nature of intermediate 25, the configuration was not rigourously established.
    • Due to the unstable nature of intermediate 25, the configuration was not rigourously established.
  • 28
    • 68949126169 scopus 로고    scopus 로고
    • Burgess, E. M.; Penton, H. R.; Taylor, E. A.; Williams, W. M. Organic Syntheses; Wiley: New York, 1988; Collect. 6, p 788.
    • Burgess, E. M.; Penton, H. R.; Taylor, E. A.; Williams, W. M. Organic Syntheses; Wiley: New York, 1988; Collect. Vol. 6, p 788.
  • 29
    • 68949094891 scopus 로고    scopus 로고
    • A single-step conversion of intermediate 24 to oxidole 26 was also possible using the Burgess reagent at high temperature; however, purification of the product was difficult.
    • A single-step conversion of intermediate 24 to oxidole 26 was also possible using the Burgess reagent at high temperature; however, purification of the product was difficult.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.