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Volumn 13, Issue 6, 2012, Pages 2597-2604

The MTHFR C677T polymorphism and prostate cancer risk: New findings from a meta-analysis of 7306 cases and 8062 controls

Author keywords

Ethnic groups; Meta analysis; MTHFR; Polymorphism; Prostate cancer risk

Indexed keywords


EID: 84874016409     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2012.13.6.2597     Document Type: Article
Times cited : (14)

References (51)
  • 1
    • 65249091990 scopus 로고    scopus 로고
    • MTHFR C677T polymorphism contributes to prostate cancer risk among Caucasians: A meta-analysis of 3511 cases and 2762 controls
    • Bai JL, Zheng MH, Xia X, et al. (2009). MTHFR C677T polymorphism contributes to prostate cancer risk among Caucasians: A meta-analysis of 3511 cases and 2762 controls. Eur J Cancer, 45, 1443-9.
    • (2009) Eur J Cancer , vol.45 , pp. 1443-1449
    • Bai, J.L.1    Zheng, M.H.2    Xia, X.3
  • 2
    • 78349291482 scopus 로고    scopus 로고
    • Association of polymorphisms in folate metabolic genes and prostate cancer risk: a casecontrol study in a Chinese population
    • Cai D, Ning L, Pan C, et al. (2010). Association of polymorphisms in folate metabolic genes and prostate cancer risk: a casecontrol study in a Chinese population. J Genet, 89, 263-7.
    • (2010) J Genet , vol.89 , pp. 263-267
    • Cai, D.1    Ning, L.2    Pan, C.3
  • 3
    • 0033970043 scopus 로고    scopus 로고
    • Folate and carcinogenesis: an integrated scheme
    • Choi SW, Mason JB, (2000). Folate and carcinogenesis: an integrated scheme. J Nutr, 130, 129-32.
    • (2000) J Nutr , vol.130 , pp. 129-132
    • Choi, S.W.1    Mason, J.B.2
  • 4
    • 4043123506 scopus 로고    scopus 로고
    • Relationship between methylenetetrahydrofolate reductase C677T and A1298C genotypes and haplotypes and prostate cancer risk and aggressiveness
    • Cicek MS, Nock NL, Li L, et al. (2004). Relationship between methylenetetrahydrofolate reductase C677T and A1298C genotypes and haplotypes and prostate cancer risk and aggressiveness. Cancer Epidemiol Biomarkers Prev, 13, 1331-6.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 1331-1336
    • Cicek, M.S.1    Nock, N.L.2    Li, L.3
  • 5
    • 34249979299 scopus 로고    scopus 로고
    • A randomized trial of folic acid for the prevention of colorectal adenomas
    • Cole BF BJ, Sandler RS, et al. (2007). A randomized trial of folic acid for the prevention of colorectal adenomas. JAMA 297, 2351-9.
    • (2007) JAMA , vol.297 , pp. 2351-2359
    • Cole, B.F.B.J.1    Sandler, R.S.2
  • 6
    • 70349331579 scopus 로고    scopus 로고
    • Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis
    • Collin SM, Metcalfe C, Zuccolo L, et al. (2009) Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis. Cancer Epidemiol Biomarkers Prev, 18, 2528-39.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 2528-2539
    • Collin, S.M.1    Metcalfe, C.2    Zuccolo, L.3
  • 7
    • 0022992740 scopus 로고
    • Meta-analysis in clinical trials
    • DerSimonian RLN, (1986). Meta-analysis in clinical trials. Control Clin Trials, 7, 177-88.
    • (1986) Control Clin Trials , vol.7 , pp. 177-188
    • Der Simonian, R.L.N.1
  • 8
    • 78650981231 scopus 로고    scopus 로고
    • Recent developments in prostate cancer biomarker research: therapeutic implications
    • Detchokul S, Frauman AG, (2011). Recent developments in prostate cancer biomarker research: therapeutic implications. Br J Clin Pharmacol, 71, 157-74.
    • (2011) Br J Clin Pharmacol , vol.71 , pp. 157-174
    • Detchokul, S.1    Frauman, A.G.2
  • 9
    • 77952890994 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer: a meta-analysis
    • Dong X, Wu J, Liang P, et al. (2010). Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer: a meta-analysis. Arch Med Res, 41, 125-33.
    • (2010) Arch Med Res , vol.41 , pp. 125-133
    • Dong, X.1    Wu, J.2    Liang, P.3
  • 10
    • 0037117501 scopus 로고    scopus 로고
    • A common mutation in the 5 10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
    • Friso S, Choi SW, Girelli D, et al. (2002). A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acad Sci U S A, 99, 5606-11.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 5606-5611
    • Friso, S.1    Choi, S.W.2    Girelli, D.3
  • 11
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, et al. (1995). A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet, 10, 111-3.
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 12
    • 0036328023 scopus 로고    scopus 로고
    • Metabolic interactions of alcohol and folate
    • Halsted CH, Villanueva JA, Devlin AM, et al. (2002). Metabolic interactions of alcohol and folate. J Nutr, 132, S2367-72.
    • (2002) J Nutr , vol.132 , pp. 2367-2372
    • Halsted, C.H.1    Villanueva, J.A.2    Devlin, A.M.3
  • 13
    • 0037444389 scopus 로고    scopus 로고
    • A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer
    • Heijmans BT, Boer JM, Suchiman HE, et al. (2003). A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer. Cancer Res, 63, 1249-53.
    • (2003) Cancer Res , vol.63 , pp. 1249-1253
    • Heijmans, B.T.1    Boer, J.M.2    Suchiman, H.E.3
  • 14
    • 0041876133 scopus 로고    scopus 로고
    • Measuring inconsistency in meta-analyses
    • Higgins JP TS, Deeks JJ, Altman DG, (2003). Measuring inconsistency in meta-analyses. BMJ, 327, 557-60.
    • (2003) BMJ , vol.327 , pp. 557-560
    • Higgins, J.P.T.S.1    Deeks, J.J.2    Altman, D.G.3
  • 15
    • 81855227033 scopus 로고    scopus 로고
    • Clinical practice Screening for prostate cancer
    • Hoffman RM, (2011). Clinical practice. Screening for prostate cancer. N Engl J Med, 365, 2013-9.
    • (2011) N Engl J Med , vol.365 , pp. 2013-2019
    • Hoffman, R.M.1
  • 16
    • 33846811416 scopus 로고    scopus 로고
    • MTHFR C677T and colorectal cancer risk: A meta-analysis of 25 populations
    • Hubner RA, Houlston RS, (2007). MTHFR C677T and colorectal cancer risk: A meta-analysis of 25 populations. Int J Cancer, 120, 1027-35.
    • (2007) Int J Cancer , vol.120 , pp. 1027-1035
    • Hubner, R.A.1    Houlston, R.S.2
  • 18
    • 34848913488 scopus 로고    scopus 로고
    • The MTHFR 677C T polymorphism and risk of prostate cancer: results from the CAPS study
    • Johansson M, Van Guelpen B, Hultdin J, et al. (2007). The MTHFR 677C -T polymorphism and risk of prostate cancer: results from the CAPS study. Cancer Causes Control, 18, 1169-74.
    • (2007) Cancer Causes Control , vol.18 , pp. 1169-1174
    • Johansson, M.1    Van Guelpen, B.2    Hultdin, J.3
  • 19
    • 78449304532 scopus 로고    scopus 로고
    • Pooled analyses of 13 prospective cohort studies on folate intake and colon cancer
    • Kim DH, Smith-Warner SA, Spiegelman D, et al. (2010) Pooled analyses of 13 prospective cohort studies on folate intake and colon cancer. Cancer Causes Control, 21, 1919-30.
    • (2010) Cancer Causes Control , vol.21 , pp. 1919-1930
    • Kim, D.H.1    Smith-Warner, S.A.2    Spiegelman, D.3
  • 20
    • 0033007272 scopus 로고    scopus 로고
    • Folate and carcinogenesis: evidence, mechanisms, and implications
    • Kim YI, (1999). Folate and carcinogenesis: evidence, mechanisms, and implications. J Nutr Biochem, 10, 66-88.
    • (1999) J Nutr Biochem , vol.10 , pp. 66-88
    • Kim, Y.I.1
  • 21
    • 3242764554 scopus 로고    scopus 로고
    • Folate, colorectal carcinogenesis, and DNA methylation: lessons from animal studies
    • Kim YI, (2004). Folate, colorectal carcinogenesis, and DNA methylation: lessons from animal studies. Environ Mol Mutagen, 44, 10-25.
    • (2004) Environ Mol Mutagen , vol.44 , pp. 10-25
    • Kim, Y.I.1
  • 22
    • 0033768152 scopus 로고    scopus 로고
    • Methyl group metabolism gene polymorphisms and susceptibility to prostatic carcinoma
    • Kimura F, Franke KH, Steinhoff C, et al. (2000). Methyl group metabolism gene polymorphisms and susceptibility to prostatic carcinoma. Prostate, 45, 225-31.
    • (2000) Prostate , vol.45 , pp. 225-231
    • Kimura, F.1    Franke, K.H.2    Steinhoff, C.3
  • 23
    • 84866331870 scopus 로고    scopus 로고
    • Effects of the MTHFR C677T Polymorphism on Prostate Specific Antigen and Prostate Cancer
    • Kucukhuseyin O, Kurnaz O, Akadam-Teker AB, et al. (2011) Effects of the MTHFR C677T Polymorphism on Prostate Specific Antigen and Prostate Cancer. Asian Pac J Cancer Prev, 12, 2275-8.
    • (2011) Asian Pac J Cancer Prev , vol.12 , pp. 2275-2278
    • Kucukhuseyin, O.1    Kurnaz, O.2    Akadam-Teker, A.B.3
  • 24
    • 58149280215 scopus 로고    scopus 로고
    • Review and pooled analysis of studies on MTHFR C677T polymorphism and esophageal cancer
    • Langevin SM, Lin D, Matsuo K, et al. (2009). Review and pooled analysis of studies on MTHFR C677T polymorphism and esophageal cancer. Toxicol Lett, 184, 73-80.
    • (2009) Toxicol Lett , vol.184 , pp. 73-80
    • Langevin, S.M.1    Lin, D.2    Matsuo, K.3
  • 25
    • 33749490522 scopus 로고    scopus 로고
    • Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis
    • Larsson SC, Giovannucci E, Wolk A, (2006). Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis. Gastroenterology, 131, 1271-83.
    • (2006) Gastroenterology , vol.131 , pp. 1271-1283
    • Larsson, S.C.1    Giovannucci, E.2    Wolk, A.3
  • 26
  • 27
    • 17744388125 scopus 로고    scopus 로고
    • A meta-analysis of the MTHFR C677T polymorphism and schizophrenia risk
    • Lewis SJ, Zammit S, Gunnell D, et al. (2005). A meta-analysis of the MTHFR C677T polymorphism and schizophrenia risk. Am J Med Genet B Neuropsychiatr Genet, 135B, 2-4.
    • (2005) Am J Med Genet B Neuropsychiatr Genet , vol.135 B , pp. 2-4
    • Lewis, S.J.1    Zammit, S.2    Gunnell, D.3
  • 28
    • 84856235306 scopus 로고    scopus 로고
    • Cruciferous vegetables intake and risk of prostate cancer: A meta-analysis
    • Liu B, Mao Q, Cao M, et al. (2012). Cruciferous vegetables intake and risk of prostate cancer: A meta-analysis. Int J Urol, 19, 134-41.
    • (2012) Int J Urol , vol.19 , pp. 134-141
    • Liu, B.1    Mao, Q.2    Cao, M.3
  • 29
    • 44949264116 scopus 로고    scopus 로고
    • Association between polymorphisms of folate-metabolizing enzymes and risk of prostate cancer
    • Marchal C, Redondo M, Reyes-Engel A, et al. (2008). Association between polymorphisms of folate-metabolizing enzymes and risk of prostate cancer. Eur J Surg Oncol, 34, 805-10.
    • (2008) Eur J Surg Oncol , vol.34 , pp. 805-810
    • Marchal, C.1    Redondo, M.2    Reyes-Engel, A.3
  • 30
    • 84874071299 scopus 로고    scopus 로고
    • Genetic aspects of folate metabolism
    • Molloy AM, (2012). Genetic aspects of folate metabolism. Subcell Biochem, 56, 105-30.
    • (2012) Subcell Biochem , vol.56 , pp. 105-130
    • Molloy, A.M.1
  • 31
    • 74049131730 scopus 로고    scopus 로고
    • The analysis of the relationship between A1298C and C677T polymorphisms of the MTHFR gene with prostate cancer in Eskisehir population
    • Muslumanoglu MH, Tepeli E, Demir S, et al. (2009). The analysis of the relationship between A1298C and C677T polymorphisms of the MTHFR gene with prostate cancer in Eskisehir population. Genet Test Mol Biomarkers, 13, 641-5.
    • (2009) Genet Test Mol Biomarkers , vol.13 , pp. 641-645
    • Muslumanoglu, M.H.1    Tepeli, E.2    Demir, S.3
  • 33
    • 34548127241 scopus 로고    scopus 로고
    • The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and cancer risk: the Croatian case-control study
    • Reljic A, Simundic AM, Topic E, et al. (2007). The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and cancer risk: the Croatian case-control study. Clin Biochem, 40, 981-5.
    • (2007) Clin Biochem , vol.40 , pp. 981-985
    • Reljic, A.1    Simundic, A.M.2    Topic, E.3
  • 34
    • 77958497609 scopus 로고    scopus 로고
    • Relationship between three polymorphisms of methylenetetrahydrofolate reductase (MTHFR C677T, A1298C, and G1793A) gene and risk of prostate cancer: a case-control study
    • Safarinejad MR, Shafiei N, Safarinejad S, (2010). Relationship between three polymorphisms of methylenetetrahydrofolate reductase (MTHFR C677T, A1298C, and G1793A) gene and risk of prostate cancer: a case-control study. Prostate, 70, 1645-57.
    • (2010) Prostate , vol.70 , pp. 1645-1657
    • Safarinejad, M.R.1    Shafiei, N.2    Safarinejad, S.3
  • 35
    • 80053239666 scopus 로고    scopus 로고
    • Screening for prostate cancer
    • Schröder FH, (2011). Screening for prostate cancer. Eur J Cancer, 47, S164-70.
    • (2011) Eur J Cancer , vol.47
    • Schröder, F.H.1
  • 36
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics the impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • Siegel R, Ward E, Brawley O, et al. (2011). Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin, 61, 212-36.
    • (2011) CA Cancer J Clin , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3
  • 37
    • 14044267729 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene and prostate cancer risk
    • Singal R, Ferdinand L, Das PM, et al. (2004) Polymorphisms in the methylenetetrahydrofolate reductase gene and prostate cancer risk. Int J Oncol, 25, 1465-71.
    • (2004) Int J Oncol , vol.25 , pp. 1465-1471
    • Singal, R.1    Ferdinand, L.2    Das, P.M.3
  • 38
    • 84874046523 scopus 로고    scopus 로고
    • Society AC Cancer Facts & Figures 2011. Atlanta: American Cancer Society
    • Society AC (2011). Cancer Facts & Figures 2011. Atlanta: American Cancer Society.
    • (2011)
  • 39
    • 16344368456 scopus 로고    scopus 로고
    • Antisense inhibition of methylenetetrahydrofolate reductase reduces cancer cell survival in vitro and tumor growth in vivo
    • Stankova J, Shang J, Rozen R, (2005). Antisense inhibition of methylenetetrahydrofolate reductase reduces cancer cell survival in vitro and tumor growth in vivo. Clin Cancer Res, 11, 2047-52.
    • (2005) Clin Cancer Res , vol.11 , pp. 2047-2052
    • Stankova, J.1    Shang, J.2    Rozen, R.3
  • 40
    • 57449098655 scopus 로고    scopus 로고
    • No association of single nucleotide polymorphisms in one-carbon metabolism genes with prostate cancer risk
    • Stevens VL, Rodriguez C, Sun J, et al. (2008). No association of single nucleotide polymorphisms in one-carbon metabolism genes with prostate cancer risk. Cancer Epidemiol Biomarkers Prev, 17, 3612-4.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 3612-3614
    • Stevens, V.L.1    Rodriguez, C.2    Sun, J.3
  • 41
    • 70350694056 scopus 로고    scopus 로고
    • Meta- and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: a HuGE-GSEC review
    • Taioli E, Garza MA, Ahn YO, et al. (2009). Meta- and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: a HuGE-GSEC review. Am J Epidemiol, 170, 1207-21.
    • (2009) Am J Epidemiol , vol.170 , pp. 1207-1221
    • Taioli, E.1    Garza, M.A.2    Ahn, Y.O.3
  • 42
    • 34547922850 scopus 로고    scopus 로고
    • Folate and cancer prevention: a closer look at a complex picture
    • Ulrich CM, (2007). Folate and cancer prevention: a closer look at a complex picture. Am J Clin Nutr, 86, 271-3.
    • (2007) Am J Clin Nutr , vol.86 , pp. 271-273
    • Ulrich, C.M.1
  • 43
    • 53349173420 scopus 로고    scopus 로고
    • Folate and cancer prevention--where to next Counterpoint
    • Ulrich CM, (2008). Folate and cancer prevention-where to next Counterpoint. Cancer Epidemiol Biomarkers Prev, 17, 2226-30.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 2226-2230
    • Ulrich, C.M.1
  • 45
    • 30044433308 scopus 로고    scopus 로고
    • Polymorphisms of methylenetetrahydrofolate reductase and the risk of prostate cancer: a nested case-control study
    • Van Guelpen BR, Wiren SM, Bergh AR, et al. (2006). Polymorphisms of methylenetetrahydrofolate reductase and the risk of prostate cancer: a nested case-control study. Eur J Cancer Prev, 15, 46-50.
    • (2006) Eur J Cancer Prev , vol.15 , pp. 46-50
    • Van Guelpen, B.R.1    Wiren, S.M.2    Bergh, A.R.3
  • 46
    • 84857805238 scopus 로고    scopus 로고
    • Cancer risk with folic acid supplements: a systematic review and meta-analysis
    • Wien TN, Pike E, Wisloff T, et al. (2012). Cancer risk with folic acid supplements: a systematic review and meta-analysis. BMJ Open, 2, e000653.
    • (2012) BMJ Open , vol.2 , pp. 000653
    • Wien, T.N.1    Pike, E.2    Wisloff, T.3
  • 47
    • 77958545987 scopus 로고    scopus 로고
    • Significant association of methylenetetrahydrofolate reductase single nucleotide polymorphisms with prostate cancer susceptibility in taiwan
    • Wu HC, Chang CH, Tsai RY, et al. (2010). Significant association of methylenetetrahydrofolate reductase single nucleotide polymorphisms with prostate cancer susceptibility in taiwan. Anticancer Res, 30, 3573-7.
    • (2010) Anticancer Res , vol.30 , pp. 3573-3577
    • Wu, H.C.1    Chang, C.H.2    Tsai, R.Y.3
  • 48
    • 84856812366 scopus 로고    scopus 로고
    • A meta-analysis of MTHFR C677T and A1298C polymorphisms and risk of acute lymphoblastic leukemia in children
    • Yan J, Yin M, Dreyer ZE, et al. (2012). A meta-analysis of MTHFR C677T and A1298C polymorphisms and risk of acute lymphoblastic leukemia in children. Pediatr Blood Cancer, 58, 513-8.
    • (2012) Pediatr Blood Cancer , vol.58 , pp. 513-518
    • Yan, J.1    Yin, M.2    Dreyer, Z.E.3
  • 49
    • 63649084874 scopus 로고    scopus 로고
    • Soy consumption and prostate cancer risk in men: a revisit of a meta-analysis
    • Yan L, Spitznagel EL, (2009). Soy consumption and prostate cancer risk in men: a revisit of a meta-analysis. Am J Clin Nutr, 89, 1155-63.
    • (2009) Am J Clin Nutr , vol.89 , pp. 1155-1163
    • Yan, L.1    Spitznagel, E.L.2
  • 50
    • 84055200205 scopus 로고    scopus 로고
    • Meta analysis of the association between MTHFR C677T polymorphism and the risk of congenital heart defects
    • Yin M, Dong L, Zheng J, et al. (2012). Meta analysis of the association between MTHFR C677T polymorphism and the risk of congenital heart defects. Ann Hum Genet, 76, 9-16.
    • (2012) Ann Hum Genet , vol.76 , pp. 9-16
    • Yin, M.1    Dong, L.2    Zheng, J.3
  • 51
    • 77956191116 scopus 로고    scopus 로고
    • MTHFR C677T polymorphism associated with breast cancer susceptibility: a meta-analysis involving 15,260 cases and 20,411 controls
    • Zhang J, Qiu LX, Wang ZH et al. (2010). MTHFR C677T polymorphism associated with breast cancer susceptibility: a meta-analysis involving 15,260 cases and 20,411 controls. Breast Cancer Res Treat, 123, 549-55.
    • (2010) Breast Cancer Res Treat , vol.123 , pp. 549-555
    • Zhang, J.1    Qiu, L.X.2    Wang, Z.H.3


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