Filament-Filament Switching Can Be Regulated by Separation Between Filaments Together with Cargo Motor Number

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Erickson, Robert P ^a   Gross, Steven P ^a   Yu, Clare C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; MYOSIN;

ACTIN FILAMENT; ARTICLE; COMPUTER SIMULATION; IN VIVO STUDY; INTRACELLULAR TRANSPORT; MICROTUBULE; MONTE CARLO METHOD; PROBABILITY; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN TRANSPORT; TRANSPORT AND BINDING PHENOMENA;

BIOLOGICAL TRANSPORT; COMPUTER SIMULATION; CYTOSKELETON; MODELS, BIOLOGICAL; MOLECULAR MOTOR PROTEINS; MONTE CARLO METHOD;

EID: 84874016077     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054298     Document Type: Article

References (14)

1. Ali MY, Krementsova EB, Kennedy GG, Mahaffy R, Pollard TD, et al. (2007) Myosin Va maneuvers through actin intersections and diffuses along microtubules. Proc Natl Acad Sci U S A 104: 4332-4336.
2. Snider J, Lin F, Zahedi N, Rodionov V, Yu CC, et al. (2004) Intracellular actin-based transport: how far you go depends on how often you switch. Proc Natl Acad Sci U S A 101: 13204-13209.
3. Schroeder HW 3rd, Mitchell C, Shuman H, Holzbaur EL, Goldman YE (2010) Motor number controls cargo switching at actin-microtubule intersections in vitro. Curr Biol 20: 687-696.
4. Ross JL, Ali MY, Warshaw DM, (2008) Cargo transport: molecular motors navigate a complex cytoskeleton. Curr Opin Cell Biol 20: 41-47.
5. Schroeder HW 3rd, Hendricks AG, Ikeda K, Shuman H, Rodionov V, et al (2012) Force-dependent detachment of Kinesin-2 biases track switching at cytoskeletal filament intersections. Biophys J 103: 48-58.
6. Gross SP, Tuma MC, Deacon SW, Serpinskaya AS, Reilein AR, et al. (2002) Interactions and regulation of molecular motors in Xenopus melanophores. J Cell Biol 156: 855-865.
7. Yildiz A, Forkey JN, McKinney SA, Ha T, Goldman YE, et al. (2003) Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localization. Science 300: 2061-2065.
8. Erickson RP, Jia Z, Gross SP, Yu CC, (2011) How molecular motors are arranged on a cargo is important for vesicular transport. PLoS Comput Biol 7: e1002032.
9. Gross SP, Vershinin M, Shubeita GT, (2007) Cargo transport: two motors are sometimes better than one. Curr Biol 17: R478-486.
10. Cheney RE, O'Shea MK, Heuser JE, Coelho MV, Wolenski JS, et al. (1993) Brain myosin-V is a two-headed unconventional myosin with motor activity. Cell 75: 13-23.
11. Isambert H, Venier P, Maggs AC, Fattoum A, Kassab R, et al. (1995) Flexibility of actin filaments derived from thermal fluctuations. Effect of bound nucleotide, phalloidin, and muscle regulatory proteins. J Biol Chem 270: 11437-11444.
12. Cassimeris L, Lingappa VR, Plopper G, Lewin B (2011) Lewin's cells. Sudbury, Mass.: Jones and Bartlett Publishers. xxiv, 1053 p.
13. Winder SJ, Ayscough KR, (2005) Actin-binding proteins. J Cell Sci 118: 651-654.
14. Taylor KA, Taylor DW, (1994) Formation of two-dimensional complexes of F-actin and crosslinking proteins on lipid monolayers: demonstration of unipolar alpha-actinin-F-actin crosslinking. Biophys J 67: 1976-1983.