Characterization and resistance mechanisms of A 5-fluorouracilresistant hepatocellular carcinoma cell line

Asian Pacific Journal of Cancer Prevention

Volumn 13, Issue 9, 2012, Pages 4807-4814

  Gu, Wei ^a   Fang, Fan Fu ^a   Li, Bai ^a   Cheng, Bin Bin ^a   Ling, Chang Quan ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

5 fluorouracil; ATP; Binding cassette transporters; Hepatocellular carcinoma; Multidrug resistance

Indexed keywords

EID: 84874005576     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2012.13.9.4807     Document Type: Article

References (35)

1. Baguley BC (2010). Multidrug resistance in cancer. Methods Mol Biol, 596, 1-14.
2. Bruix J, Sherman M; Practice Guidelines Committee, American Association for the Study of Liver Diseases (2005). Management of hepatocellular carcinoma. Hepatology, 42, 1208-36.
3. Chen R, Zhu D, Ye X, et al (1980). Establishment of three human liver carcinoma cell lines and some of their biological characteristics in vitro. Sci Sin, 23, 236-47.
4. Dai ZQ, Wang R, Ling SK, et al (2007). Simulated microgravity inhibits the proliferation and osteogenesis of rat bone marrow mesenchymal stem cells. Cell Prolif, 40, 671-84.
5. Durand RE, Olive PL (1981). Flow cytometry studies of intracellular adriamycin in single cells in vitro. Cancer Res, 41(9 Pt 1), 3489-94.
6. El-Serag HB (2011). Hepatocellular carcinoma. N Engl J Med, 365, 1118-27.
7. Ferlay J, Shin HR, Bray F, et al (2010). GLOBOCAN 2008, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet]. Lyon, France: International Agency for Research on Cancer. Available from: http:// globocan.iarc.fr
8. Frustaci S, Bearz A, Basso B, et al (2003). Efficacy of oxaliplatin and 5-fluorouracil in hepatocarcinoma (HCC). Proc Am Soc Clin Oncol, 22, (abstr 1346).
9. Green SK, Francia G, Isidoro C, Kerbel RS (2004). Antiadhesive antibodies targeting E-cadherin sensitize multicellular tumor spheroids to chemotherapy in vitro. Mol Cancer Ther, 3, 149-59.
10. Guglielmi A, Aschele C, Grossi F, et al (1996). Alternating bolus and continuous infusion 5-fluorouracil: a strategy to overcome resistance to this fluoropyrimidine in advanced colorectal cancer patients. Cytotechnology, 19, 215-9.
11. Han KQ, Huang G, Gu W, et al (2007). Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumor model of human hepatocellular carcinoma in nude mice. World J Gastroenterol, 13, 3374-9.
12. Huai-Yun H, Secrest DT, Mark KS, et al (1998). Expression of multidrug resistance-associated protein (MRP) in brain microvessel endothelial cells. Biochem Biophys Res Commun, 243, 816-20.
13. Jianmin Z, Hongfang W, Meifu F (2002). Resistance of multicellular aggregates to pharmorubicin observed in human hepatocarcinoma cells. Braz J Med Biol Res, 35, 255-60.
14. Jin J, Huang M, Wei HL, Liu GT (2002). Mechanism of 5-fluorouracil required resistance in human hepatocellular carcinoma cell line Bel(7402). World J Gastroenterol, 8, 1029-34.
15. Li B, Ye T, Zhao L, et al (2006). Effects of multidrug resistance, antisense RNA on the chemosensitivity of hepatocellular carcinoma cells. Hepatobiliary Pancreat Dis Int, 5, 552-9.
16. Li G, Chen X, Wang Q, et al (2007). The roles of four multi-drug resistance proteins in hepatocellular carcinoma multidrug resistance. J Huazhong Univ Sci Technolog Med Sci, 27, 173-5.
17. Li YX, Lin ZB, Tan HR (2004). Wild type p53 increased chemosensitivity of drug-resistant human hepatocellular carcinoma Bel7402/5-FU cells. Acta Pharmacol Sin, 25, 76-82.
18. Livraghi T, Mäkisalo H, Line PD (2011). Treatment options in hepatocellular carcinoma today. Scand J Surg, 100, 22-9.
19. Marin JJ, Romero MR, Briz O (2010). Molecular bases of liver cancer refractoriness to pharmacological treatment. Curr Med Chem, 17, 709-40.
20. Meta-analysis Group In Cancer (1998). Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. J Clin Oncol, 16, 301-8.
21. Pétriz J, García-López J (1997). Flow cytometric analysis of P-glycoprotein function using rhodamine 123. Leukemia, 11, 1124-30.
22. Qin S, Thongprasert S, Lim HY, et al (2010). Oxaliplatin + 5-fluorouracil/leucovorin (FOLFOX4) in advanced HCC: updated efficacy results of the EACH trial. Ann Oncol, 21(Suppl 8), 826P.
23. Ryu SH, Chung YH (2010). How to overcome multidrug resistance in chemotherapy for advanced hepatocellular carcinoma. Liver Int, 30, 496-8.
24. Shaffer LG, Tommerup N, ed (2005). ISCN 2005: An International System for Human Cytogenetic Nomenclature. S. Karger, Basel, Switzerland.
25. Sun Z, Zhao Z, Li G, et al (2010). Relevance of two genes in the multidrug resistance of hepatocellular carcinoma: in vivo and clinical studies. Tumori, 96, 90-6.
26. Tong SW, Yang YX, Hu HD, et al (2012). Proteomic investigation of 5-fluorouracil resistance in a human hepatocellular carcinoma cell line. J Cell Biochem, 113, 1671-80.
27. Uchibori K, Kasamatsu A, Sunaga M, et al (2012). Establishment and characterization of two 5-fluorouracil-resistant hepatocellular carcinoma cell lines. Int J Oncol, 40, 1005-10.
28. Wilson TR, Johnston PG, Longley DB (2009). Anti-apoptotic mechanisms of drug resistance in cancer. Curr Cancer Drug Targets, 9, 307-19.
29. Wrzesinski SH, Taddei TH, Strazzabosco M (2011). Systemic therapy in hepatocellular carcinoma. Clin Liver Dis, 15, 423-41.
30. Yan F, Wang XM, Liu ZC, et al (2010). JNK1, JNK2, and JNK3 are involved in P-glycoprotein-mediated multidrug resistance of hepatocellular carcinoma cells. Hepatobiliary Pancreat Dis Int, 9, 287-95.
31. Yang JX, Luo Y, Qiu HM, Tang WX (2009). Characterization and resistance mechanisms of cisplatin-resistant human hepatocellular carcinoma cell line. Saudi Med J, 30, 35-40.
32. Yunis JJ (1981). New chromosome techniques in the study of human neoplasia. Hum Pathol, 12, 540-9.
33. Zhai BJ, Shao ZY, Zhao CL, et al (2006). Development and characterization of multidrug resistant human hepatocarcinoma cell line in nude mice. World J Gastroenterol, 12, 6614-9.
34. Zhou J, Cheng SC, Luo D, Xie Y (2001). Study of multi-drug resistant mechanisms in a taxol-resistant hepatocellular carcinoma QGY-TR 50 cell line. Biochem Biophys Res Commun, 280, 1237-42.
35. Zhou Y, Ling XL, Li SW, et al (2010). Establishment of a human hepatoma multidrug resistant cell line in vitro. World J Gastroenterol, 16, 2291-7.