It takes more than cells to make a good lung

American Journal of Respiratory and Critical Care Medicine

Volumn 187, Issue 4, 2013, Pages 342-346

  Weibel, Ewald R ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; OXYGEN;

ANATOMY; BRONCHIOLE; BRONCHUS; ELECTRON MICROSCOPY; HUMAN; LUNG ALVEOLUS; LUNG ALVEOLUS EPITHELIUM; LUNG BLOOD FLOW; LUNG BLOOD VESSEL; LUNG CAPILLARY; LUNG DIFFUSION; LUNG DIFFUSION CAPACITY; LUNG DISEASE; LUNG FUNCTION; LUNG GAS EXCHANGE; LUNG PERFUSION; LUNG RESISTANCE; LUNG VENTILATION; MYOFIBROBLAST; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY VENTILATOR; RESPIRATORY AIRFLOW; REVIEW; SACCULUS; SECRETORY CELL; SMOOTH MUSCLE FIBER; TRACHEA;

HUMANS; LUNG; REFERENCE VALUES;

EID: 84873977425     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201212-2260OE     Document Type: Review

References (39)

1. Richards DW. Right heart catheterization: its contributions to physiology and medicine [Nobel Lecture]. Science 1957;125:1181-1185.
2. Gomez DM. Hémodynamique et angiocinétique. Paris: Hermann; 1941.
3. Weibel ER, Gomez DM. Architecture of the human lung. Science 1962; 137:577-585.
4. Roughton FJW, Forster RE. Relative importance of diffusion and chemical reaction rates in determining rate of exchange of gases in the human lung, with special reference to true diffusing capacity of pulmonary membrane and volume of blood in the lung capillaries. J Appl Physiol 1957;11:290-302.
5. Bohr C. Ueber die spezifische Tätigkeit der Lungen bei der respiratorischen Gasaufnahme. Skand Arch Physiol 1909;22:221-280.
6. Krogh A. On the mechanism of gas-exchange in the lungs. Skand Arch Physiol 1911;23:248-278.
7. Weibel ER, Knight BW. A morphometric study on the thickness of the pulmonary air-blood barrier. J Cell Biol 1964;21:367-384.
8. Weibel ER. Morphometric estimation of pulmonary diffusion capacity. I. Model and method. Respir Physiol 1970/71;11:54-75.
9. Weibel E R. Morphological basis of alveolar-capillary gas exchange. Physiol Rev 1973;53:419-495.
10. Weibel ER, Federspiel WJ, Fryder-Doffey F, Hsia CCW, König M, Stalder-Navarro V, Vock R. Morphometric model for pulmonary diffusing capacity. I. Membrane diffusing capacity. Respir Physiol 1993;93:125-149.
11. Weibel ER. Morphometry of the human lung. Heidelberg and New York: Springer Verlag and Academic Press; 1963.
12. Gehr P, Bachofen M, Weibel ER. The normal human lung: ultrastructure and morphometric estimation of diffusion capacity. Respir Physiol 1978;32:121-140.
13. Hammond MD, Hempleman SC. Oxygen diffusing capacity estimates derived from measured VA/Q distributions in man. Respir Physiol 1987;69:129-147.
14. Weibel ER. What makes a good lung? Swiss Med Wkly 2009;139:375- 386.
15. Mandelbrot B. The fractal geometry of nature. New York: Freeman; 1983.
16. Weibel ER. Fractal geometry: a design principle for living organisms. Am J Physiol 1991;261:L361-L369.
17. Burri PH. Lung development and histogenesis. In: Fishman AP, Fisher AB, editors. Handbook of physiology: respiration, Vol. 4. Washington, DC: American Physiological Society; 1984, pp. 1-46.
18. Haefeli-Bleuer B, Weibel ER. Morphometry of the human pulmonary acinus. Anat Rec 1988;220:401-414.
19. Hess WR. Das Prinzip des kleinsten Kraftverbrauches im Dienste hämodynamischer Forschung. Archiv für Anatomie und Physiologie: Physiologische Abt 1914;1:1-59.
20. Murray CD. The physiological principle of minimum work. I. The vascular system and the cost of blood. Proc Natl Acad Sci USA 1926;12: 207-214.
21. Sapoval B, Filoche M, Weibel ER. Smaller is better - but not too small: a physical scale for the design of the mammalian pulmonary acinus. Proc Natl Acad Sci USA 2001;99:10411-10416.
22. Weibel ER, Sapoval B, Filoche M. Design of peripheral airways for efficient gas exchange. Respir Physiol Neurobiol 2005;148:3-21.
23. Swan AJ, Tawhai MH. Evidence for minimal oxygen heterogeneity in the healthy human pulmonary acinus. J Appl Physiol 2011;110:528- 537.
24. Mead J, Whittenberger JL, Radford EP. Surface tension as a factor in pulmonary volume-pressure hysteresis. J Appl Physiol 1957;10:191- 196.
25. Weibel ER. Looking into the lung, what can it tell us? Am J Radiol 1979; 133:1021-1031.
26. Weibel ER. The pathway for oxygen: structure and function in the mammalian respiratory system. Cambridge: Harvard University Press; 1984.
27. Fuller B. Tensegrity. Portfolio and Art News Annual 1961;4:112-127.
28. Ingber DE, Tensegrity I: cell structure and hierarchical systems biology. J Cell Sci 2003;116:1157-1173.
29. Wilson TA, Bachofen H. A model for mechanical structure of the alveolar duct. J Appl Physiol 1982;52:1064-1070.
30. Clements JA, Hustead RF, Johnson RP, Gribetz I. Pulmonary surface tension and alveolar stability. J Appl Physiol 1961;16:444-450.
31. Bachofen H, Gehr P, Weibel ER. Alterations of mechanical properties and morphology in excised rabbit lungs rinsed with a detergent. J Appl Physiol 1979;47:1002-1010.
32. Hajari AJ, Yablonskiy DA, Sukstanskii AL, Quirk JD, Conradi MS, Woods JC. Morphometric changes in the human pulmonary acinus during inflation. J Appl Physiol 2012;112:937-943.
33. Schürch S, Goerke J, Clements JA. Direct determination of volume and time dependence of alveolar surface tension in excised lungs. Proc Natl Acad Sci USA 1978;75:3417-3421.
34. Bachofen H, Schürch S, Urbinelli M, Weibel ER. Relations among alveolar surface tension, surface area, volume, and recoil pressure. J Appl Physiol 1987;62:1878-1887.
35. West JB. How well designed is the human lung? Am J Respir Crit Care Med 2006;173:583-584.
36. Duncker HR. The lung air sac system of birds. Adv Anat Embryol Cell Biol 1971;45:1-171.
37. Cardoso WV, Lü J. Regulation of early lung morphogenesis: questions, facts and controversies. Development 2006;133:1611-1624.
38. Metzger RJ, Krasnow MA. Genetic control of branching morphogenesis. Science 1999;284:1635-1639.
39. Metzger RJ, Klein OD, Martin G, Krasnow MA. The branching programme of mouse lung development. Nature 2008;453:745-750.