Circulating epithelial cells in patients with thyroid carcinoma can they be identified in the blood?;Zirkulierende epitheliale Zellen bei Patienten mit schilddrüsenkarzinom lassen sie sich im blut nachweisen?

NuklearMedizin

Volumn 52, Issue 1, 2013, Pages 7-13

  Winkens, T ^a   Pachmann, K ^b   Freesmeyer, M ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

CEC; Circulating epithelial cells; Differentiated thyroid carcinoma; EpCAM

Indexed keywords

EPITHELIAL CELL ADHESION MOLECULE; THYROGLOBULIN;

ARTICLE; CELL DIFFERENTIATION; CIRCULATING TUMOR CELL; CONTROLLED STUDY; DIFFERENTIATED THYROID CANCER; DISTANT METASTASIS; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; LYMPH NODE; MAJOR CLINICAL STUDY; PILOT STUDY; THYROID DISEASE; THYROIDECTOMY;

ADULT; AGED; ANTIGENS, NEOPLASM; CELL ADHESION MOLECULES; EPITHELIAL CELLS; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASTIC CELLS, CIRCULATING; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; THYROID NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 84873960834     PISSN: 00295566     EISSN: None     Source Type: Journal    
DOI: 10.3413/Nukmed-0524-12-08     Document Type: Article

References (28)

1. Baeuerle PA, Gires O. EpCAM (CD326) finding its role in cancer. Br J Cancer 2007; 96: 417-423.
2. Balzar M, Winter MJ, de Boer CJ, Litvinov SV. The biology of the 17-1A antigen (Ep-CAM). J Mol Med 1999; 77: 699-712.
3. Camara O, Kavallaris A, Nöschel H et al. Seeding of epithelial cells into circulation during surgery for breast cancer: the fate of malignant and benign mobilized cells. World J Surg Oncol 2006; 4: 67.
4. Cristofanilli M, Budd G, Ellis M et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med 2004; 351: 781-791.
5. Ensinger C, Kremser R, Prommegger R et al. EpCAM overexpression in thyroid carcinomas: a histopathological study of 121 cases. J Immuno--ther 2006; 29: 569-573.
6. Fehm T, Sagalowsky A, Clifford E et al. Cytogenetic evidence that circulating epithelial cells in patients with carcinoma are malignant. Clin Cancer Res 2002; 8: 2073-2084.
7. Giovanella L, Maffioli M, Ceriani L et al. Unstimulated high sensitive thyroglobulin measurement predicts outcome of differentiated thyroid carcinoma. Clin Chem Lab Med 2009; 47: 1001-1004.
8. Gupta M, Chia S. Circulating thyroid cancer markers. Curr Opin Endocrinol Diabetes Obes 2007; 14: 383-388.
9. Hay ID, Gonzalez-Losada T, Reinalda MS et al. Long-term outcome in 215 children and adolescents with papillary thyroid cancer treated during 1940 through 2008. World J Surg 2010; 34: 1192-1202.
10. Hekimian K, Meisezahl S, Trompelt K et al. Epithelial cell dissemination and readhesion: analysis of factors contributing to metastasis formation in breast cancer. ISRN Oncol 2012; 2012: 601810.
11. Hocevar M, Auersperg M, Stanovnik L. The dynamics of serum thyroglobulin elimination from the body after thyroid surgery. Eur J Surg Oncol 1997; 23: 208-210.
12. Kloos RT. Thyroid cancer recurrence in patients clinically free of disease with undetectable or very low serum thyroglobulin values. J Clin Endocrinol Metab 2010; 95: 5241-5248.
13. Langley RR, Fidler IJ. The seed and soil hypothesis revisited - the role of tumor-stroma interactions in metastasis to different organs. Int J Cancer 2011; 128: 2527-2535.
14. Pachmann K, Camara O, Kavallaris A et al. Quantification of the response of circulating epithelial cells to neoadjuvant treatment for breast cancer: a new tool for therapy monitoring. Breast Cancer Res 2005; 7: R975-R979.
15. Pachmann K, Clement JH, Schneider C-P et al. Standardized quantification of circulating peripheral tumor cells from lung and breast cancer. Clin Chem Lab Med 2005; 43: 617-627.
16. Pachmann K, Camara O, Kavallaris A et al. Monitoring the response of circulating epithelial tumor cells to adjuvant chemotherapy in breast cancer allows detection of patients at risk of early relapse. J Clin Oncol 2008; 26: 1208-1215.
17. Pachmann K, Camara O, Kroll T et al. Efficacy control of therapy using circulating epithelial tumor cells (CETC) as "liquid biopsy": trastuzumab in HER2/neu-positive breast carcinoma. J Cancer Res Clin Oncol 2011; 137: 1317-1327.
18. Pachmann U, Hekimian K, Carl S, Ruediger N, Rabenstein C, Pachmann K. Comparing Sequential Steps For Detection Of Circulating Tumor Cells: More Specific Or Just Less Sensitive? Webmed--Central CANCER 2011; 2: WMC001490.
19. Pantel K, Deneve E, Nocca D et al. Circulating epithelial cells in patients with benign colon diseases. Clin Chem 2012; 58: 936-940.
20. Paterlini-Brechot P, Benali NL. Circulating tumor cells (CTC) detection: Clinical impact and future directions. Cancer Lett 2007; 253: 180-204.
21. Patriarca C, Macchi RM, Marschner AK, Mellstedt H. Epithelial cell adhesion molecule expression (CD326) in cancer: A short review. Cancer Treat Rev 2012; 38: 68-75.
22. Podsypanina K, Du YCN, Jechlinger M et al. Seeding and propagation of untransformed mouse mammary cells in the lung. Science 2008; 321: 1841-1844.
23. Rao CG, Chianese D, Doyle GV et al. Expression of epithelial cell adhesion molecule in carcinoma cells present in blood and primary and metastatic tumors. Int J Oncol 2005; 27: 49-57.
24. 18F)fluoro--2-deoxy-D-glucose-positron emission tomography scanning. J Clin Endocrinol Metab 2005; 91: 498-505.
25. Robert-Koch-Institut. Verbreitung von Krebs-- erkrankungen in Deutschland. Berlin 2010.
26. Rolle A, Günzel R, Pachmann U et al. Increase in number of circulating disseminated epithelial cells after surgery for non-small cell lung cancer monitored by MAINTRAC(R) is a predictor for relapse: A preliminary report. World J Surg Oncol 2005; 3: 18.
27. Shoup M, Stojadinovic A, Nissan A et al. Prognostic indicators of outcomes in patients with distant metastases from differentiated thyroid carcinoma. J Am Coll Surg 2003; 197: 191-197.
28. Trzpis M, McLaughlin PMJ, de Leij LMFH, Harmsen MC. Epithelial cell adhesion molecule: more than a carcinoma marker and adhesion molecule. Am J Pathol 2007; 171: 386-395.