Effects of oral L-carnitine supplementation on lipid profile, anemia, and quality of life in chronic renal disease patients under hemodialysis: A randomized, double-blinded, placebo-controlled trial

Journal of Nutrition and Metabolism

Volumn 2012, Issue , 2012, Pages

  Emami Naini, Afsoon ^a   Moradi, Mahnaz ^a   Mortazavi, Mojgan ^a   Amini Harandi, Asghar ^b   Hadizadeh, Mehdi ^a   Shirani, Farhad ^a   Basir Ghafoori, Hamed ^c   Emami Naini, Pardis ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b JAHROM UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84873879405     PISSN: 20900724     EISSN: 20900732     Source Type: Journal    
DOI: 10.1155/2012/510483     Document Type: Article

References (20)

1. Hosseinpanah F., Kasraei F., Nassiri A. A., Azizi F., High prevalence of chronic kidney disease in Iran: a large population-based study. BMC Public Health 2009 9 1, article 44 2-s2.0-62849109317 10.1186/1471-2458-9-44
2. Shoji T., Nishizawa Y., Chronic kidney disease as a metabolic syndrome with malnutrition-need for strict control of risk factors. Internal Medicine 2005 44 3 179 187 2-s2.0-17744366393 10.2169/internalmedicine.44.179 (Pubitemid 40575895)
3. Tsimihodimos V., Dounousi E., Siamopoulos K. C., Dyslipidemia in chronic kidney disease: an approach to pathogenesis and treatment. American Journal of Nephrology 2008 28 6 958 973 2-s2.0-53549111038 10.1159/000144024
4. Vaziri N. D., Moradi H., Mechanisms of dyslipidemia of chronic renal failure. Hemodialysis International 2006 10 1 1 7 2-s2.0-33144484038 10.1111/j.1542-4758.2006.01168.x (Pubitemid 43263285)
5. Bellinghieri G., Santoro D., Calvani M., Mallamace A., Savica V., Carnitine and hemodialysis. American Journal of Kidney Diseases 2003 41 3, supplement S112 S126 2-s2.0-0037374348
6. Arduini A., Bonomini M., Savica V., Amato A., Zammit V., Carnitine in metabolic disease: potential for pharmacological intervention. Pharmacology and Therapeutics 2008 120 2 149 156 2-s2.0-53749084068 10.1016/j.pharmthera.2008.08. 008
7. Reuter S. E., Faull R. J., Evans A. M., L-carnitine supplementation in the dialysis population: are Australian patients missing out? Nephrology 2008 13 1 3 16 2-s2.0-38149012408 10.1111/j.1440-1797.2007.00817.x
8. Bossola M., Muscaritoli M., Tazza L., Giungi S., Tortorelli A., Fanelli F. R., Luciani G., Malnutrition in hemodialysis patients: what therapy? American Journal of Kidney Diseases 2005 46 3 371 386 2-s2.0-23944474820 10.1053/j.ajkd.2005.05.031 (Pubitemid 41208173)
9. Hurot J. M., Cucherat M., Haugh M., Fouque D., Effects of L-carnitine supplementation in maintenance hemodialysis patients: a systematic review. Journal of the American Society of Nephrology 2002 13 3 708 714 2-s2.0-0036192012 (Pubitemid 34183936)
10. Saghaei M., Random allocation software for parallel group randomized trials. BMC Medical Research Methodology 2004 4, article 26 2-s2.0-12344300756 10.1186/1471-2288-4-26 (Pubitemid 40132139)
11. Montazeri A., Goshtasebi A., Vahdaninia M., Gandek B., The Short Form Health Survey (SF-36): translation and validation study of the Iranian version. Quality of Life Research 2005 14 3 875 882 2-s2.0-17744366880 10.1007/s11136-004-1014-5 (Pubitemid 40576872)
12. Tanzer F., Hizel S., Çetinkaya O., Sekreter E., Serum free carnitine and total triglycerid levels in children with iron deficiency anemia. International Journal for Vitamin and Nutrition Research 2001 71 1 66 69 2-s2.0-0035096296 (Pubitemid 32205804)
13. Karanth J., Jeevaratnam K., Effect of dietary lipid, carnitine and exercise on lipid profile in rat blood, liver and muscle. Indian Journal of Experimental Biology 2009 47 9 748 753 2-s2.0-70349306897
14. Karanth J., Jeevaratnam K., Effect of carnitine supplementation on mitochondrial enzymes in liver and skeletal muscle of rat after dietary lipid manipulation and physical activity. Indian Journal of Experimental Biology 2010 48 5 503 510 2-s2.0-77954259596
15. Massy Z. A., Ma J. Z., Louis T. A., Kasiske B. L., Lipid-lowering therapy in patients with renal disease. Kidney International 1995 48 1 188 198 2-s2.0-0029051951
16. Shojaei M., Djalali M., Khatami M., Siassi F., Eshraghian M., Effects of carnitine and coenzyme Q10 on lipid profile and serum levels of lipoprotein(a) in maintenance hemodialysis patients on statin therapy. Iranian journal of kidney diseases 2011 5 2 114 118 2-s2.0-79958723473
17. Semeniuk J., Shalansky K. F., Taylor N., Jastrzebski J., Cameron E. C., Evaluation of the effect of intravenous l-carnitine on quality of life in chronic hemodialysis patients. Clinical Nephrology 2000 54 6 470 477 2-s2.0-0033663345
18. Rathod R., Baig M. S., Khandelwal P. N., Kulkarni S. G., Gade P. R., Siddiqui S., Results of a single blind, randomized, placebo-controlled clinical trial to study the effect of intravenous L-carnitine supplementation on health-related quality of life in Indian patients on maintenance hemodialysis. Indian Journal of Medical Sciences 2006 60 4 143 153 2-s2.0-33646450266
19. Sloan R. S., Kastan B., Rice S. I., Sallee C. W., Yuenger N. J., Smith B., Ward R. A., Brier M. E., Golper T. A., Quality of life during and between hemodialysis treatments: role of L- carnitine supplementation. American Journal of Kidney Diseases 1998 32 2 265 272 2-s2.0-0031928405
20. Savica V., Santoro D., Mazzaglia G., Ciolino F., Monardo P., Calvani M., Bellinghieri G., Kopple J. D., L-carnitine infusions may suppress serum C-reactive protein and improve nutritional status in maintenance hemodialysis patients. Journal of Renal Nutrition 2005 15 2 225 230 2-s2.0-11844262893 10.1053/j.jrn.2004.10.002