The bovine CD1D gene has an unusual gene structure and is expressed but cannot present α-galactosylceramide with a C26 fatty acid

International Immunology

Volumn 25, Issue 2, 2013, Pages 91-98

  Nguyen, Thi Kim Anh ^a   Koets, Ad P ^a   Vordermeier, Martin ^b   Jervis, Peter J ^c   Cox, Liam R ^c   Graham, Simon P ^b   Santema, Wiebren J ^a   Moody, D Branch ^d   Van calenbergh, Serge ^e   Zajonc, Dirk M ^f   Besra, Gurdyal S ^c   Van rhijn, Ildiko ^a,d  

^a UTRECHT UNIVERSITY   (Netherlands)

^b VETERINARY LABORATORIES AGENCY   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e GHENT UNIVERSITY   (Belgium)

^f LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

Animal models; CD1; Immunogenetics; Natural killer T cells (NKT cells)

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN; CYTOKINE; FATTY ACID; GLYCOSPHINGOLIPID;

ARTICLE; BODY TEMPERATURE; CELL SURFACE; COW; CYTOKINE RELEASE; EXON; GENE EXPRESSION; GENE STRUCTURE; HUMAN; HUMAN CELL; INTRON; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSLATION;

ANIMALS; ANTIGENS, CD1D; BASE SEQUENCE; BODY TEMPERATURE; CATTLE; CELL LINE; CYTOKINES; FATTY ACIDS; GALACTOSYLCERAMIDES; GENE EXPRESSION; HUMANS; LIGANDS; MICE; NATURAL KILLER T-CELLS;

EID: 84873872795     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxs092     Document Type: Article

References (38)

1. Gumperz, J. E., Miyake, S., Yamamura, T. and Brenner, M. B. 2002. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J. Exp. Med. 195:625.
2. Lee, P. T., Benlagha, K., Teyton, L. and Bendelac, A. 2002. Distinct functional lineages of human V(alpha)24 natural killer T cells. J. Exp. Med. 195:637.
3. Snyder-Cappione, J. E., Tincati, C., Eccles-James, I. G. et al. 2010. A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males. PLoS One. 5:e15412.
4. Brossay, L., Chioda, M., Burdin, N. et al. 1998. CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution. J. Exp. Med. 188:1521.
5. Matsuda, J. L., Naidenko, O. V., Gapin, L. et al. 2000. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J. Exp. Med. 192:741.
6. Benlagha, K., Weiss, A., Beavis, A., Teyton, L. and Bendelac, A. 2000. In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers. J. Exp. Med. 191:1895.
7. Baker, M. L. and Miller, R. D. 2007. Evolution of mammalian CD1: marsupial CD1 is not orthologous to the eutherian isoforms and is a pseudogene in the opossum Monodelphis domestica. Immunology. 121:113.
8. Van Rhijn, I., Koets, A. P., Im, J. S. et al. 2006. The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d. J. Immunol. 176:4888.
9. Looringh van Beeck, F. A., Reinink, P., Hermsen, R. et al. 2009. Functional CD1d and/or NKT cell invariant chain transcript in horse, pig, African elephant and guinea pig, but not in ruminants. Mol. Immunol. 46:1424.
10. Coad, M., Clifford, D., Rhodes, S. G., Hewinson, R. G., Vordermeier, H. M. and Whelan, A. O. 2010. Repeat tuberculin skin testing leads to desensitisation in naturally infected tuberculous cattle which is associated with elevated interleukin-10 and decreased interleukin-1 beta responses. Vet. Res. 41:14.
11. Howard, C. J., Sopp, P., Parsons, K. R., Bembridge, G. P. and Hall, G. 1993. A new bovine leukocyte antigen cluster comprising two monoclonal antibodies, CC43 and CC118, possibly related to CD1. Vet. Immunol. Immunopathol. 39:69.
12. Exley, M., Garcia, J., Balk, S. P. and Porcelli, S. 1997. Requirements for CD1d recognition by human invariant Valpha24+ CD4-CD8- T cells. J. Exp. Med. 186:109.
13. de Jong, A., Peña-Cruz, V., Cheng, T. Y., Clark, R. A., Van Rhijn, I. and Moody, D. B. 2010. CD1a-autoreactive T cells are a normal component of the human aß T cell repertoire. Nat. Immunol. 11:1102.
14. Brigl, M., van den Elzen, P., Chen, X. et al. 2006. Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors. J. Immunol. 176:3625.
15. Brossay, L., Tangri, S., Bix, M., Cardell, S., Locksley, R. and Kronenberg, M. 1998. Mouse CD1-autoreactive T cells have diverse patterns of reactivity to CD1+ targets. J. Immunol. 160:3681.
16. Jervis, P. J., Cox, L. R. and Besra, G. S. 2011. Synthesis of a versatile building block for the preparation of 6-N-derivatized α-galactosyl ceramides: rapid access to biologically active glycolipids. J. Org. Chem. 76:320.
17. Chen, J., Narayan, S. B., Edinger, A. L. and Bennett, M. J. 2012. Flow injection tandem mass spectrometric measurement of ceramides of multiple chain lengths in biological samples. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 883-884:136.
18. Kaiser, C. A., Preuss, D., Grisafi, P. and Botstein, D. 1987. Many random sequences functionally replace the secretion signal sequence of yeast invertase. Science. 235:312.
19. + T cells and natural killer cells is essential for the antimetastatic effect of alpha-galactosylceramide. Blood. 99:1259.
20. Fujii, S., Shimizu, K., Hemmi, H. et al. 2006. Glycolipid alpha-Cgalactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice. Proc. Natl. Acad. Sci. U.S.A. 103:11252.
21. + T cells: their cytokine production and hepatotoxicity in vivo and in vitro. J. Immunol. 169:6127.
22. Woltman, A. M., Ter Borg, M. J., Binda, R. S. et al. 2009. Alphagalactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial. Antivir. Ther. (Lond.). 14:809.
23. Motohashi, S., Nagato, K., Kunii, N. et al. 2009. A phase I-II study of alpha-galactosylceramide-pulsed IL-2/GM-CSF-cultured peripheral blood mononuclear cells in patients with advanced and recurrent non-small cell lung cancer. J. Immunol. 182:2492.
24. Renukaradhya, G. J., Manickam, C., Khatri, M. et al. 2011. Functional invariant NKT cells in pig lungs regulate the airway hyperreactivity: a potential animal model. J. Clin. Immunol. 31:228.
25. Piccione, G., Caola, G. and Refinetti, R. 2003. Daily and estrous rhythmicity of body temperature in domestic cattle. BMC Physiol. 3:7.
26. Kasumov, T., Huang, H., Chung, Y. M., Zhang, R., McCullough, A. J. and Kirwan, J. P. 2010. Quantification of ceramide species in biological samples by liquid chromatography electrospray ionization tandem mass spectrometry. Anal. Biochem. 401:154.
27. Pettus, B. J., Kroesen, B. J., Szulc, Z. M. et al. 2004. Quantitative measurement of different ceramide species from crude cellular extracts by normal-phase high-performance liquid chromatography coupled to atmospheric pressure ionization mass spectrometry. Rapid Commun. Mass Spectrom. 18:577.
28. Zhou, D., Mattner, J., Cantu, C. et al. 2004. Lysosomal glycosphingolipid recognition by NKT cells. Science. 306:1786.
29. Wu, D. Y., Segal, N. H., Sidobre, S., Kronenberg, M. and Chapman, P. B. 2003. Cross-presentation of disialoganglioside GD3 to natural killer T cells. J. Exp. Med. 198:173.
30. Jahng, A., Maricic, I., Aguilera, C., Cardell, S., Halder, R. C. and Kumar, V. 2004. Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide. J. Exp. Med. 199:947.
31. Gumperz, J. E., Roy, C., Makowska, A. et al. 2000. Murine CD1d-restricted T cell recognition of cellular lipids. Immunity. 12:211.
32. Brennan, P. J., Tatituri, R. V., Brigl, M. et al. 2011. Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals. Nat. Immunol. 12:1202.
33. Kinjo, Y., Wu, D., Kim, G. et al. 2005. Recognition of bacterial glycosphingolipids by natural killer T cells. Nature. 434:520.
34. Kinjo, Y., Tupin, E., Wu, D. et al. 2006. Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat. Immunol. 7:978.
35. Arrenberg, P., Halder, R., Dai, Y., Maricic, I. and Kumar, V. 2010. Oligoclonality and innate-like features in the TCR repertoire of type II NKT cells reactive to a beta-linked self-glycolipid. Proc. Natl. Acad. Sci. U.S.A. 107:10984.
36. Van Rhijn, I., Young, D. C., Im, J. S. et al. 2004. CD1d-restricted T cell activation by nonlipidic small molecules. Proc. Natl. Acad. Sci. U.S.A. 101:13578.
37. Godfrey, D. I., MacDonald, H. R., Kronenberg, M., Smyth, M. J. and Van Kaer, L. 2004. NKT cells: what's in a name? Nat. Rev. Immunol. 4:231.
38. Borg, N. A., Wun, K. S., Kjer-Nielsen, L. et al. 2007. CD1d-lipidantigen recognition by the semi-invariant NKT T-cell receptor. Nature. 448:44