Mechanism of action of neisseria gonorrhoeae o-acetylpeptidoglycan esterase, an SGNH serine esterase

Journal of Biological Chemistry

Volumn 288, Issue 4, 2013, Pages 2605-2613

  Pfeffer, John M ^a   Weadge, Joel T ^a,b   Clarke, Anthony J ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b WILFRID LAURIER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; BINDING STUDIES; CARBOHYDRATE ESTERASE; CATALYTIC RESIDUE; CATALYTIC TRIAD; CELL WALLS; CLASSIFICATION SYSTEM; CONSERVED RESIDUES; KINETIC CHARACTERIZATION; KINETIC STUDY; MECHANISM OF ACTION; NEISSERIA GONORRHOEAE; O-ACETYL GROUP; OXYANION HOLE; PEPTIDOGLYCANS; REACTION MECHANISM; SEQUENCE SIMILARITY; STRUCTURE AND FUNCTION RELATIONSHIP; SUBSTRATE BINDING; THREE-DIMENSIONAL STRUCTURE;

AMINO ACIDS; CARBOHYDRATES; HYDROLASES; THREE DIMENSIONAL;

ESTERS;

APE1A PROTEIN; ASPARAGINE; GLYCINE; HISTIDINE; SERINE; SERINE PROTEINASE; THREONINE; UNCLASSIFIED DRUG; VALINE;

ALPHA HELIX; ARTICLE; BETA SHEET; BINDING SITE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; ENZYME LOCALIZATION; ENZYME SUBSTRATE; NEISSERIA GONORRHOEAE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; SEQUENCE ALIGNMENT; STRUCTURE ANALYSIS;

ACETYLESTERASE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIONS; BINDING SITES; CATALYTIC DOMAIN; CIRCULAR DICHROISM; ESCHERICHIA COLI; ESTERASES; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEISSERIA GONORRHOEAE; PEPTIDOGLYCAN; PROTEIN CONFORMATION; SERINE;

EID: 84873845734     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.436352     Document Type: Article

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